Studies on antidermatophytic effect of Allamanda cathertica

Authors

  • Ainun Nahar Institute of Biological Sciences, Rajshahi University, Rajshahi
  • Syed Ashrafuzzaman Department of Pharmacology, Sir Salimullah Medical College, Dhaka
  • M. N. Islam Department of Zoology, Rajshahi University, Rajshahi
  • M. Shah Alam Department of Botany, Rajshahi University, Rajshahi

DOI:

https://doi.org/10.3329/bjp.v5i1.4610

Keywords:

Allamanda cathertica, Antifungal activity, Dermatophytoses

Abstract

Antidermatophytic activity of dichloromethane and methanol extracts of whole plant of Allamandacathertica was evaluated. Two pathogenic dermatophytes Trichophyton rubrum and Microsporum gypseum were used that were collected from dermatophytoses patients.The dichloromethane extract was moderately active at concentration of 50 µg/disc but exhibited highly potent activity at concentration of 200 µg/disc.  The methanol extract was not active against the tested fungi. Dichloromethane extract of A.cathertica may have antidermatophyte constituents that could be useful in ringworm diseases.

Downloads

Download data is not yet available.
Abstract
1064
Download
709 Read
326

References

Acharya TK, Chatterjee IB. Isolation of chrysophanic acid-9- anthrone, the major antifungal principle of Cassia tora. Lloydia. 1975; 38: 218-20.

Anonymous. Allamanda cathertica. The wealth of India. 1:A. CSIR: New Delhi, 1985, pp 248-49.

Bauer AW, Kirby WM, Sherris JC, Turck M. Antibiotic susceptibility testing by standardized single disc method. Am J Clin Pathol. 1966; 45: 493-96.

Ghani A. Medicinal plants of Bangladesh. Asiatic Society of Bangladesh, Dhaka, 1st ed. 1998, pp 69-70.

Irobi ON, Daramola SO. Antifungal activities of crude extracts of Mitracarpus villosus (Rubiaceae). J Ethnopharmacol. 1993; 40: 137-40.

Kader HAA, Seddek SR, El-Shanawany AA. In vitro study of the effect of some medicinal plants on the growth of some dermatophytes. Assiut Veterinary Med J. 1989; 34: 36-42.

Masuduzzaman S, Meah MB, Rashid MM. Determination of inhibitory action of Allamanda leaf extracts against some important plant pathogens. J Agric Rural Dev. 2008; 6: 107-13.

Onawunmi GO. Evaluation of the antifungal activity of Lemon grass oil. Int J Crude Drug Res. 1989; 27: 121-26.

Singh S, Singh SK, Tripathi SC. Fungitoxic properties of essential oil of Eucalyptus rostrata. Indian Perfumer. 1988; 32: 190-93.

Tiwari TN, Pandey VB, Dubey NK. Plumieride from Allamanda cathertica as an antidermatophytic agent. Phytother Res. 2002; 16: 393-94.

Additional Files

Published

2010-03-14

How to Cite

Nahar, A., S. Ashrafuzzaman, M. N. Islam, and M. S. Alam. “Studies on Antidermatophytic Effect of Allamanda Cathertica”. Bangladesh Journal of Pharmacology, vol. 5, no. 1, Mar. 2010, pp. 5-7, doi:10.3329/bjp.v5i1.4610.

Issue

Section

Research Articles