Troponin I level in risk stratification of non-ST-elevation myocardial infarction in smokers
DOI:
https://doi.org/10.3329/bjp.v5i2.6666Keywords:
Myocardial infarction, Troponin I, SmokerAbstract
A prospective study was carried out to evaluate the role of troponin I in risk stratification of non-ST-elevation myocardial infarction in 40 smoker and 40 non-smoker patients. The troponin I was significantly higher (p<0.001) in smokers (35.5 ± 5.22 ng/mL) than non-smoker (0.27 ± 0.01 ng/mL). The duration of hospital stay was longer in Group I (106.6 ± 2.36 hour) than in Group II (49.20 ± 1.01 hour). The major adverse cardiac event was higher in smoker (71.79%) compared to non-smokers (10.8%). So, it may be concluded that higher value of troponin I with history of smoking in non-ST-elevation myocardial infarction may be considered as 'high risk group' patients.
Downloads
202
94 Read
3
References
Adams JE, Bodor GS, Davila-Roman VG, Delmez JA, Apple FS, Ladenson JH, Jaffe AS. Cardiac troponin I: A marker with high specificity for cardiac injury. Circulation 1993; 88: 101-06.
Alp NJ, Bell JA, Shahi M. A rapid troponin I based protocol for assessing acute chest pain. QJM. 2001; 94: 687-94.
Antman EM, Tanasijevic MJ, Thompson B, Schactman M, McCabe CH, Cannon CP, Fischer GA, Fung AY, Thompson C, Wybenga D, Braunwald E. Cardiac-specific troponin I level to predict the risk of mortality in patient with acute coronary syndrome. N Engl J Med. 1996; 335: 1342-49.
Black HR. Smoking and cardiovascular disease. In: Hypertension: Pathophysiology, diagnosis and management. Largh JH, Brenner BM (eds). 2nd edi. New York, Ravan Press Ltd., 1995, pp 2621-47.
Cummins B, Auckland ML, Cummins P. Cardiac-specific troponin-I radioimmunoassay in the diagnosis of acute myocardial infarction. Am Heart J. 1987; 113: 1333-44.
Gardner C, McMillan MD. Development of arteriosclerosis. Am J Cardiol. 1973; 31: 542-46.
Hamm CW, Goldmann BU, Heeschen C, Kreymann G, Berger J, Meinertz T. Emergency room triage of patient with acute chest pain by means of rapid testing for cardiac troponin T or troponin I. N Engl J Med. 1997; 337: 1648-53.
Main C, Palmer S, Griffin S, Jones L, Orton V, Sculpher M, Henderson R, Sudlow C, Hawkins N, Riemsma R. Clopidogrel used in combination with aspirin compared with aspirin alone in treatment of non-ST-segment-elevation acute coronary syndrome: A systematic review and economic evaluation. Health Technol Assess. 2004; 8: 1-141.
Mayhan WG, Sharpe GM. Effect of cigarette smoke extract on arteriolar dilatation in vivo. J Appl Physiol. 1996; 81: 1996-2003.
Millat MH. Smoking is hazardous to health. The Daily Star. January 2, 2005.
Sabatine MS, Morrow DA, de Lemos JA, Gibson CM, Murphy SA, Rifai N, McCabe C, Antman EM, Cannon CP, Braunwald E. Multimarker approach to risk stratification in non-ST elevation acute coronary syndrome: Simultaneous assessment of troponin I, C-reactive protein, B-type natriuretic peptide. Circulation 2002; 105: 1760-63.
Additional Files
Published
How to Cite
Issue
Section
License
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
