Pharmacological mechanism of a drug pair of astragali and cinnamon in shiquan dabu decoction

Authors

  • Hui Yan School of Biological and Chemical Engineering, Jiangsu University of Science and Technology, Zhenjiang
  • Mingzhu Jiang School of Biological and Chemical Engineering, Jiangsu University of Science and Technology, Zhenjiang
  • Qiongying Wu School of Biological and Chemical Engineering, Jiangsu University of Science and Technology, Zhenjiang
  • Zhongzheng Gui School of Biological and Chemical Engineering, Jiangsu University of Science and Technology, Zhenjiang

DOI:

https://doi.org/10.3329/bjp.v5i2.7769

Keywords:

Shiquan dabu decoction, Drug pair, Blood deficiency, Qi deficiency.

Abstract

The pharmacological mechanism of drug pair of astragali and cinnamon in shiquan dabu decoction were studied in blood deficiency and Qi deficiency modeled mice. In Qi deficiency, the drug pair of astragali and cinnamon in shiquan dabu decoction had the ability of improving the number of white blood cells and peyer patches, and T cell activity. It had no action in red blood cell number and phagocytic activity of peritoneal macrophage, and B cell activity. In blood deficiency, the drug pair of astragali and cinnamon in shiquan dabu decoction had the effect of improving the hemoglobin content and T cell activity. It did not affect the number of white blood cells and peyer patches, phagocytic activity of peritoneal macrophage and B cell activity. In conclusion, the drug pair of astragali and cinnamon in shiquan dabu decoction has different actions, the quantity of drug pair in shiquan decoction should be changed according to the symptoms in process of diseases.

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References

Cao Y, Xia QH, Meng H, Zhong AP. Pharmacological effects of serum containing Chinese medicine Bushen Huayu Jiedu compound recipe in lung cancer drug-resistance cells. Chin J Integr Med. 2008; 14: 46-50.

Chen LY, Luo X. Effects of Zhigancao Decoction on arrhythmia with syndrome of deficiency of both Qi and blood in rats. Shizhen Guo Yi Guo Yao. 2010; 21: 1631-33.

Chen Y, Li XR, Zhao J, Zhou T, Zou Q. Chemical component analysis of volatile oil in drug pair Herba Ephedrae-Ramulus Cinnamomi by GC-MS and CRM. J Cent South Univ Technol. 2007; 14: 509-13.

Li XD, Pan WS, Nie SF, Wu LJ. Studies on controlled release effervescent osmotic pump tablets from Traditional Chinese Medicine Compound Recipe. J Controlled Release. 2004; 96: 359-67.

Liu Y, Li XH. Preliminary molecular basis of Dangguibuxuetang on Qi deficiency and blood stasis syndrome. J Shenyang Pharm Univ. 2008; Z1: 110-11.

Song HT, Guo T, Zhang RH, Zheng CL, Ma Y, Li X. Preparation of the traditional Chinese medicine compound recipe heart-protecting musk pH-dependent gradient-release pellets. Drug Dev Ind Pharm. 2002; 28: 1261-73.

Sun E. Changes in some elements, enzymes and energy charge in skeletal muscle of rats with spleen qi deficiency. Chin J Integr Med. 1993; 13: 736-38.

Wang YJ, Shi Q, Jiang JC, Bian Q, Liang QQ, Li CG, Zhou Q, Cui XJ, Lu S, Zhou CJ. Mechanism of Yiqi Huayu Bushen recipe in treating cervical syndrome in rats with qi deficiency, blood stasis and kidney deficiency. Chin J Integr Med. 2009; 7: 53-58.

Yang LH, Qiu JD, Li HQ. Effects of astragalus heteropolysaccharides on erythrocyte immune adherence function of mice with adjuvant-induced arthritis. Acta Pharma Sin. 2009; 44: 1364-70.

Yang QL. Determination of sucrose in shiquan dabu gao by optical rotation. Zhong Yao Tong Bao. 1986; 11: 32-33.

You QY, Wang P. The studies of Ziziphi Spinosae Decoction (ZSD) intervention to old rats syndrome model with Yin and blood-deficiency (sic) and sleep deprivation. J Pharmacol Sci. 2009; 109(Suppl. 1): 247.

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Published

2011-06-05

How to Cite

Yan, H., M. Jiang, Q. Wu, and Z. Gui. “Pharmacological Mechanism of a Drug Pair of Astragali and Cinnamon in Shiquan Dabu Decoction”. Bangladesh Journal of Pharmacology, vol. 5, no. 2, June 2011, pp. 107-11, doi:10.3329/bjp.v5i2.7769.

Issue

Vol. 5 No. 2 (2010)

Section

Research Articles

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