Computational selections of terpenes present in the plant Calotropis gigantea as mosquito larvicide’s by blocking the sterol carrying protein, AeSCP-2

Authors

  • P. Suresh Kumar Department of Environmental Science, Faculty of Marine Sciences, CAS in Marine Biology, Annamalai University, Parangipettai 608502
  • A. Chezhian Department of Environmental Science, Faculty of Marine Sciences, CAS in Marine Biology, Annamalai University, Parangipettai 608502
  • P. Senthil Raja Department of Zoology, Annamalai University, Chidambaram 608001
  • J. Sathiyapriya Department of Biochemistry, Annamalai University, Chidambaram 608001

DOI:

https://doi.org/10.3329/bjp.v7i1.8414

Keywords:

Calotropis gigantea, Mosquito larvicidal, Phytochemical, Terpenes

Abstract

The present study reports the phytochemical properties of Calotropis gigantea (Asclepiadaceae) commonly known as milk weed. In addition, in silico docking analysis was also carried out to assess the mosquito larvicidal potential of three terpene compounds isolated from C. gigantea. Considerable amount of primary metabolites, essential macro and micro nutrients were documented in the plant. The GC-MS analysis of the chloroform extract revealed the presence of eight terpenes in the plant. From the docking studies it is evident that ?-amyrin has a great potential against AeSCP-2. The phytochemical screening and docking results gives strong baseline information for the posterity.

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Author Biographies

P. Suresh Kumar, Department of Environmental Science, Faculty of Marine Sciences, CAS in Marine Biology, Annamalai University, Parangipettai 608502

Assistant Professor

A. Chezhian, Department of Environmental Science, Faculty of Marine Sciences, CAS in Marine Biology, Annamalai University, Parangipettai 608502

Assistant Professor

P. Senthil Raja, Department of Zoology, Annamalai University, Chidambaram 608001

Assistant Professor

J. Sathiyapriya, Department of Biochemistry, Annamalai University, Chidambaram 608001

Research Scholar

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Published

2012-01-22

How to Cite

Suresh Kumar, P., A. Chezhian, P. Senthil Raja, and J. Sathiyapriya. “Computational Selections of Terpenes Present in the Plant Calotropis Gigantea As Mosquito larvicide’s by Blocking the Sterol Carrying Protein, AeSCP-2”. Bangladesh Journal of Pharmacology, vol. 7, no. 1, Jan. 2012, pp. 1-5, doi:10.3329/bjp.v7i1.8414.

Issue

Vol. 7 No. 1 (2012)

Section

Research Articles

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