Occurrence of coronary artery disease in patients with type 2 diabetes mellitus can be predicted by neutrophil lymphocyte ratio

Authors

  • Mohammad Monzurul Alam Bhuiyan Clinical Pathologist, Department of Clinical Pathology, Dhaka Medical College Hospital, Dhaka
  • Md Saiful Islam Assistant Professor, Department of Clinical Pathology, BSMMU, Dhaka
  • Sheuli Ferdousi Assistant Professor, Department of Clinical Pathology, BSMMU, Dhaka
  • Dhiman Borua Medical Officer, Chittagong General Hospital, Chittagong
  • Mousumi Ghosh Assistant Professor, Department of Pathology, Monno Medical College & Hospital, Manikgong
  • Sharmin Akter Assistant Registrar, Department of Obstetrics & Gynaecology, ICMH, Matuail, Dhaka
  • Syed Md Jabed Assistant Professor, Department of Medicine, University of Science & Technology of Chittagong, Chittagong
  • Tuhin Sultana Associate Professor, Department of Clinical Pathology, BSMMU, Dhaka
  • AN Nashimuddin Ahmed Professor, Department of Clinical Pathology, BSMMU, Dhaka

DOI:

https://doi.org/10.3329/bmj.v44i3.27371

Keywords:

Nutrophil lymphocyte ratio, diabetes mellitus, coronary artery disease

Abstract

Neutrophil lymphocyte ratio (NLR) is the sign of balance between neutrophil & lymphocyte levels in the body and is an indicator of systemic inflammation. NLR is a new predictor for cardiovascular risk and mortality and by which occurrence of coronary artery disease can be predicted in type 2 DM patients. This case control study was conducted in the Department of Clinical pathology in collaboration with Department of Cardiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka from March 2014 to February 2015 to assess the NLR as a useful predictive marker for coronary artery disease in type 2 DM patients detected by coronary angiography. Total 134 patients waiting for coronary angiography in the Department of Cardiology, BSMMU were enrolled in this study. Among them, 84 patients were considered as Group A (DM with CAD). All of them had ? 50% coronary artery stenosis on coronary angiography. Fifty patients with DM but without CAD were enrolled in Group B and considered as controls. Statistically significant increased NLR was found in Group A (type 2 DM patients with CAD) compared to Group B (type 2 DM patients without CAD). So, NLR can be used to predict adverse outcome i.e. coronary artery disease in patients with type 2 DM.

Bangladesh Med J. 2015 Sep; 44 (3): 130-135

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Author Biography

Mohammad Monzurul Alam Bhuiyan, Clinical Pathologist, Department of Clinical Pathology, Dhaka Medical College Hospital, Dhaka



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Published

2016-04-17

How to Cite

Bhuiyan, M. M. A., Islam, M. S., Ferdousi, S., Borua, D., Ghosh, M., Akter, S., Jabed, S. M., Sultana, T., & Ahmed, A. N. (2016). Occurrence of coronary artery disease in patients with type 2 diabetes mellitus can be predicted by neutrophil lymphocyte ratio. Bangladesh Medical Journal, 44(3), 130–135. https://doi.org/10.3329/bmj.v44i3.27371

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