Association between Chronic Idiopathic Urticaria and Helicobacter Pylori Infection

Abstract

Chronic idiopathic urticaria (CIU) is a recalcitrant skin disease characterized by pruritic wheals lasting more than six
weeks in the absence of a physical cause. A case-control type of analytical study was conducted from January 2012 to
August 2012 on patients of chronic idiopathic urticaria attending the outpatient department of Dermatology and
Venereology, Bangabandhu Sheikh Mujib Medical University, Dhaka. The objective of the study was to see the
association between chronic idiopathic urticaria and Helicobacter pylori infection. In serum, IgG positive individuals,
female covers about two-thirds (14 respondents with 73.3%) than male counterparts (5 respondents with 26.3%).
Among the IgG negative individuals, females were again more in percentage (63.6%) and males were 36.4%. Serum
IgG for H. Pylori positive respondents were highest among the students (42.1%) followed by housewives (31.6%)
and in IgG negative individuals, the same trend exists. When we considered education level for IgG positivity, it was
found that graduate and above educated respondents showed higher results (42.1%) and SSC level showed next
incidences (26.3%). In IgG negative group, the same trend exists. We found the same positivity for IgG of H. pylori
among the different food intake, heat, and sunlight exposed history respectively whereas food intake history covers
more in IgG negative individuals. Most of the IgG positive respondents were ill-looking (94.7%), though IgG
negative individuals were also ill-looking. Chronic idiopathic urticaria is a disorder that often baffles dermatologists
and allergists alike. Without a known cause, it is nearly impossible to prescribe an effective treatment.

Bangabandhu Sheikh Mujib Med. Coll. J. 2022;1(1):20-23