COVID-19 and Diabetes: Acknowledging the Bidirectional Link

Authors

  • Mohammad Rezaul Quader Associate Prof and head, Dept. of Biochemistry, Bangabandhu Sheikh Mujib Medical College, Faridpur.
  • Mohammad Jahidur Rahman Khan Assistant Professor, Dept. of Microbiology, Shaheed Suhrawardy Medical College, Dhaka.
  • Arifa Akram Assistant Professor, Dept. of Virology, National Institute of Laboratory Medicine and Referral Center, Dhaka.
  • Md Shahidul Islam Program Manager, Non Communicable Disease Control Program, Directorate General of Health Services (DGHS), Dhaka.
  • Nusrat Mannan Assistant Professor, Dept. of Microbiology, US-Bangla Medical College and Hospital, Narayanganj.
  • Md Sabir Hossain Professor, Dept. of Biochemistry and Molecular Biology, Jahangirnagar University, Dhaka
  • Nurul Karim Professor, Dept. of Biochemistry and Molecular Biology, Jahangirnagar University, Dhaka
  • Farha Matin Juliana Professor, Dept. of Biochemistry and Molecular Biology, Jahangirnagar University, Dhaka
  • Amirul Huda Bhuiyan Lecturer, Dhaka Medical College, Dhaka.
  • Paroma Deb Medical Officer, Mollapara Union Health Centre, Sunamganj.
  • Farhana Khatoon Assistant Professor, Dept. of Gynaecological Oncology, Bangabandhu Sheikh Mujib Medical University, Dhaka.
  • Farzana Mim Lab Consultant, Molecular Diagnostics Laboratory, Bangabandhu Sheikh Mujib Medical College, Faridpur.
  • Md Selim Reza Lab Consultant, Molecular Diagnostics Laboratory, Bangabandhu Sheikh Mujib Medical College, Faridpur.

DOI:

https://doi.org/10.3329/bsmmcj.v1i2.69349

Keywords:

COVID-19, Diabetes mellitus, Hyperglycemia, SARS-CoV-2, Cytokine storm

Abstract

COVID-19 and diabetes mellitus have a dynamic and bidirectional relationship. Diabetes is a risk factor for COVID-19. Diabetes mellitus is linked to hypercoagulability, inflammation, hyperglycemia, and other conditions (obesity, hypertension, cardiovascular disease, chronic kidney disease). Hyperglycemia may worsen SARS-CoV-2 infection. As a result of direct pancreatic damage caused by COVID-19, the stress response is triggered response to infection (including cytokine storm), including the use of hyperglycemic prescription medications such as corticosteroids for severe COVID-19, new-onset hyperglycemia and diabetes have been linked to the virus, as well as rapidly deteriorating blood glucose control in pre-existing diabetes. Insulin resistance and decreased b-cell secretion cause hyperglycemia. Challenges still remain in establishing the connection between COVID-19 and diabetes, whilst the
pandemic progresses.

Bangabandhu Sheikh Mujib Med. Coll. J. 2022;1(2):99-103

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Published

2023-10-13

How to Cite

Quader, M. R. ., Khan, M. J. R. ., Akram, A. ., Islam, M. S. ., Mannan, N. ., Hossain, M. S., Karim, N. ., Juliana, F. M. ., Bhuiyan, A. H. ., Deb, P. ., Khatoon, F. ., Mim, F. ., & Reza, . M. S. . (2023). COVID-19 and Diabetes: Acknowledging the Bidirectional Link. Bangabandhu Sheikh Mujib Medical College Journal, 1(2), 99–103. https://doi.org/10.3329/bsmmcj.v1i2.69349

Issue

Section

Review Article