Outcome of trial of labour for vaginal birth after one caesarean section
Authors
Reefaat Rahman
Department of Obstetrics and Gynaecology, Bangladesh Medical University, Dhaka, Bangladesh
Begum Nasrin
Department of Obstetrics and Gynaecology, Bangladesh Medical University, Dhaka, Bangladesh
Tarafder Runa Laila
Department of Obstetrics and Gynaecology, Bangladesh Medical University, Dhaka, Bangladesh
Farzana Aktar
Department of Obstetrics and Gynaecology, Dhaka Medical College Hospital, Dhaka, Bangladesh
Nurun Nahar Khanam
Department of Obstetrics and Gynaecology, Bangladesh Medical University, Dhaka, Bangladesh
DOI:
Keywords
VBAC, TOLAC, caesarean section, outcomeDownloads
Correspondence
Publication history
Responsible editor
Reviewer
Funding
Dated 25 Jan 2023
Ethical approval
Trial registration number
Copyright
Published by Bangladesh Medical University (former Bangabandhu Sheikh Mujib Medical University).
Methods: This cross-sectional study was conducted in the Department of Obstetrics and Gynaecology, Bangabandhu Sheikh Mujib Medical University (currently, Bangladesh Medical University), Dhaka, Bangladesh, from January 2023 to December 2024. This study included 162 pregnant women with a history of one C/S attending the Obstetrics and Gynaecology department of BSMMU.
Results: Most of the participants (75.3%) were between 21–30 years old. Among the women who attempted TOLAC, 33.3% successfully had a VBAC, while 66.7% required an emergency repeat cesarean section. Fetal distress (51.3%) was the most common reason for the previous cesarean and the main cause of emergency repeat cesarean section after failed trial, which is 48.2%. Babies born through VBAC had satisfactory neonatal outcomes, with 90.7% having a good Apgar score (>7) compared to 75.9% in the emergency repeat caesarean section (ERCS) group.
Conclusion: This study found that fetal distress is a major factor leading to ERCS and underscores the better neonatal outcomes and lower postpartum hemorrhage rates in VBAC deliveries.
Vaginal birth after cesarean section (VBAC), the term that describes a vaginal delivery in a woman who has given birth via cesarean section in a previous pregnancy. Patients desiring VBAC delivery need to undergo a trial of labor, popularly known as a trial of labor after cesarean section (TOLAC). Delivery by cesarean section has increased significantly worldwide. In the United States, this rate increased from 5% in 1970 to 32.9% in 2009 and 31.9% in 2016 [1]. Several efforts failed to achieve the 15% cesarean delivery rate recommended by WHO [2].

Groups based on pre-test marks | Pretest | Posttest Marks (%) | Difference in pre and post-test marks (mean improvement) | P |
Didactic lecture classes | ||||
<50% | 36.6 (4.8) | 63.2 (9.4) | 26.6 | <0.001 |
≥50% | 52.8 (4.5) | 72.4 (14.9) | 19.6 | <0.001 |
Flipped classes | ||||
<50% | 36.9 (4.7) | 82.2 (10.8) | 45.4 | <0.001 |
≥50% | 52.8 (4.6) | 84.2 (10.3) | 31.4 | <0.001 |
Data presented as mean (standard deviation) | ||||
Background characteristics | Number (%) |
Age at presentation (weeks)a | 14.3 (9.2) |
Gestational age at birth (weeks)a | 37.5 (2.8) |
Birth weight (grams)a | 2,975.0 (825.0) |
Sex |
|
Male | 82 (41) |
Female | 118 (59) |
Affected side |
|
Right | 140 (70) |
Left | 54 (27) |
Bilateral | 6 (3) |
Delivery type |
|
Normal vaginal delivery | 152 (76) |
Instrumental delivery | 40 (20) |
Cesarean section | 8 (4) |
Place of delivery |
|
Home delivery by traditional birth attendant | 30 (15) |
Hospital delivery by midwife | 120 (60) |
Hospital delivery by doctor | 50 (25) |
Prolonged labor | 136 (68) |
Presentation |
|
Cephalic | 144 (72) |
Breech | 40 (20) |
Transverse | 16 (8) |
Shoulder dystocia | 136 (68) |
Maternal diabetes | 40 (20) |
Maternal age (years)a | 27.5 (6.8) |
Parity of mother |
|
Primipara | 156 (78) |
Multipara | 156 (78) |
aMean (standard deviation), all others are n (%) | |
Background characteristics | Number (%) |
Age at presentation (weeks)a | 14.3 (9.2) |
Gestational age at birth (weeks)a | 37.5 (2.8) |
Birth weight (grams)a | 2,975.0 (825.0) |
Sex |
|
Male | 82 (41) |
Female | 118 (59) |
Affected side |
|
Right | 140 (70) |
Left | 54 (27) |
Bilateral | 6 (3) |
Delivery type |
|
Normal vaginal delivery | 152 (76) |
Instrumental delivery | 40 (20) |
Cesarean section | 8 (4) |
Place of delivery |
|
Home delivery by traditional birth attendant | 30 (15) |
Hospital delivery by midwife | 120 (60) |
Hospital delivery by doctor | 50 (25) |
Prolonged labor | 136 (68) |
Presentation |
|
Cephalic | 144 (72) |
Breech | 40 (20) |
Transverse | 16 (8) |
Shoulder dystocia | 136 (68) |
Maternal diabetes | 40 (20) |
Maternal age (years)a | 27.5 (6.8) |
Parity of mother |
|
Primipara | 156 (78) |
Multipara | 156 (78) |
aMean (standard deviation), all others are n (%) | |
Mean escape latency of acquisition day | Groups | ||||
NC | SC | ColC | Pre-SwE Exp | Post-SwE Exp | |
Days |
|
|
|
|
|
1st | 26.2 (2.3) | 30.6 (2.4) | 60.0 (0.0)b | 43.2 (1.8)b | 43.8 (1.6)b |
2nd | 22.6 (1.0) | 25.4 (0.6) | 58.9 (0.5)b | 38.6 (2.0)b | 40.5 (1.2)b |
3rd | 14.5 (1.8) | 18.9 (0.4) | 56.5 (1.2)b | 34.2 (1.9)b | 33.8 (1.0)b |
4th | 13.1 (1.7) | 17.5 (0.8) | 53.9 (0.7)b | 35.0 (1.6)b | 34.9 (1.6)b |
5th | 13.0 (1.2) | 15.9 (0.7) | 51.7 (2.0)b | 25.9 (0.7)b | 27.7 (0.9)b |
6th | 12.2 (1.0) | 13.3 (0.4) | 49.5 (2.0)b | 16.8 (1.1)b | 16.8 (0.8)b |
Average of acquisition days | |||||
5th and 6th | 12.6 (0.2) | 14.6 (0.8) | 50.6 (0.7)b | 20.4 (2.1)a | 22.4 (3.2)a |
NC indicates normal control; SC, Sham control; ColC, colchicine control; SwE, swimming exercise exposure. aP <0.05; bP <0.01. | |||||
Categories | Number (%) |
Sex |
|
Male | 36 (60.0) |
Female | 24 (40.0) |
Age in yearsa | 8.8 (4.2) |
Education |
|
Pre-school | 20 (33.3) |
Elementary school | 24 (40.0) |
Junior high school | 16 (26.7) |
Cancer diagnoses |
|
Acute lymphoblastic leukemia | 33 (55) |
Retinoblastoma | 5 (8.3) |
Acute myeloid leukemia | 4 (6.7) |
Non-Hodgkins lymphoma | 4 (6.7) |
Osteosarcoma | 3 (5) |
Hepatoblastoma | 2 (3.3) |
Lymphoma | 2 (3.3) |
Neuroblastoma | 2 (3.3) |
Medulloblastoma | 1 (1.7) |
Neurofibroma | 1 (1.7) |
Ovarian tumour | 1 (1.7) |
Pancreatic cancer | 1 (1.7) |
Rhabdomyosarcoma | 1 (1.7) |
aMean (standard deviation) | |



Narakas classification | Total 200 (100%) | Grade 1 72 (36%) | Grade 2 64 (32%) | Grade 3 50 (25%) | Grade 4 14 (7%) |
Complete recoverya | 107 (54) | 60 (83) | 40 (63) | 7 (14) | - |
Near complete functional recovery but partial deformitya | 22 (11) | 5 (7) | 10 (16) | 6 (12) | 1 (7) |
Partial recovery with gross functional defect and deformity | 31 (16) | 7 (10) | 13 (20) | 10 (20) | 1 (7) |
No significant improvement | 40 (20) | - | 1 (1.5) | 27 (54) | 12 (86) |
aSatisfactory recovery bGrade 1, C5, 6, 7 improvement; Grade 2, C5, 6, 7 improvement; Grade 3, panpalsy C5, 6, 7, 8, 9, Grade 4, panpalsy with Hornon’s syndrome. | |||||
Narakas classification | Total 200 (100%) | Grade-1 72 (36%) | Grade-2 64 (32%) | Grade-3 50 (25%) | Grade-4 14 (7%) |
Complete recoverya | 107 (54) | 60 (83) | 40 (63) | 7 (14) | - |
Near complete functional recovery but partial deformitya | 22 (11) | 5 (7) | 10 (16) | 6 (12) | 1 (7) |
Partial recovery with gross functional defect and deformity | 31 (16) | 7 (10) | 13 (20) | 10 (20) | 1 (7) |
No significant improvement | 40 (20) | - | 1 (1.5) | 27 (54) | 12 (86) |
aSatisfactory recovery bGrade 1, C5, 6, 7 improvement; Grade 2, C5, 6, 7 improvement; Grade 3, panpalsy C5, 6, 7,8,9, Grade 4, panpalsy with Hornon’s syndrome. | |||||
Variables in probe trial day | Groups | ||||
NC | SC | ColC | Pre-SwE Exp | Post-SwE Exp | |
Target crossings | 8.0 (0.3) | 7.3 (0.3) | 1.7 (0.2)a | 6.0 (0.3)a | 5.8 (0.4)a |
Time spent in target | 18.0 (0.4) | 16.2 (0.7) | 5.8 (0.8)a | 15.3 (0.7)a | 15.2 (0.9)a |
NC indicates normal control; SC, Sham control; ColC, colchicine control; SwE, swimming exercise exposure. aP <0.01. | |||||
Pain level | Number (%) | P | ||
Pre | Post 1 | Post 2 | ||
Mean (SD)a pain score | 4.7 (1.9) | 2.7 (1.6) | 0.8 (1.1) | <0.001 |
Pain categories | ||||
No pain (0) | - | 1 (1.7) | 31 (51.7) | <0.001 |
Mild pain (1-3) | 15 (25.0) | 43 (70.0) | 27 (45.0) | |
Moderete pain (4-6) | 37 (61.7) | 15 (25.0) | 2 (3.3) | |
Severe pain (7-10) | 8 (13.3) | 2 (3.3) | - | |
aPain scores according to the visual analogue scale ranging from 0 to 10; SD indicates standard deviation | ||||
Surgeries | Number (%) | Satisfactory outcomes n (%) |
Primary surgery (n=24) |
|
|
Upper plexus | 6 (25) | 5 (83) |
Pan-palsy | 18 (75) | 6 (33) |
All | 24 (100) | 11 (46) |
Secondary Surgery (n=26) |
|
|
Shoulder deformity | 15 (58) | 13 (87) |
Wrist and forearm deformity | 11 (42) | 6 (54) |
All | 26 (100) | 19 (73) |
Primary and secondary surgery | 50 (100) | 30 (60) |
Mallet score 14 to 25 or Raimondi score 2-3 or Medical Research grading >3 to 5. | ||
Narakas classification | Total 200 (100%) | Grade-1 72 (36%) | Grade-2 64 (32%) | Grade-3 50 (25%) | Grade-4 14 (7%) |
Complete recoverya | 107 (54) | 60 (83) | 40 (63) | 7 (14) | - |
Near complete functional recovery but partial deformitya | 22 (11) | 5 (7) | 10 (16) | 6 (12) | 1 (7) |
Partial recovery with gross functional defect and deformity | 31 (16) | 7 (10) | 13 (20) | 10 (20) | 1 (7) |
No significant improvement | 40 (20) | - | 1 (1.5) | 27 (54) | 12 (86) |
aSatisfactory recovery bGrade 1, C5, 6, 7 improvement; Grade 2, C5, 6, 7 improvement; Grade 3, panpalsy C5, 6, 7,8,9, Grade 4, panpalsy with Hornon’s syndrome. | |||||
Trials | Groups | ||||
NC | SC | ColC | Pre-SwE Exp | Post-SwE Exp | |
1 | 20.8 (0.6) | 22.1 (1.8) | 41.1 (1.3)b | 31.9 (1.9)b | 32.9 (1.8)a, b |
2 | 10.9 (0.6) | 14.9 (1.7) | 37.4 (1.1)b | 24.9 (2.0)b | 26.8 (2.5)b |
3 | 8.4 (0.5) | 9.9 (2.0) | 32.8 (1.2)b | 22.0 (1.4)b | 21.0 (1.4)b |
4 | 7.8 (0.5) | 10.4 (1.3) | 27.6(1.1)b | 12.8 (1.2)b | 13.0 (1.4)b |
Savings (%)c | 47.7 (3.0) | 33.0 (3.0) | 10.0 (0.9)b | 23.6 (2.7)b | 18.9 (5.3)b |
NC indicates normal control; SC, Sham control; ColC, colchicine control; SwE, swimming exercise exposure. aP <0.05; bP <0.01. cThe difference in latency scores between trials 1 and 2, expressed as the percentage of savings increased from trial 1 to trial 2 | |||||



This study was conducted in the Department of Obstetrics and Gynaecology, Bangabandhu Sheikh Mujib Medical University (currently, Bangladesh Medical University) Dhaka, Bangladesh, from January 2023 to December 2024. This study included 162 pregnant women with a history of one cesarean section (C/S) between 37 weeks and 41 weeks of gestation who attended the inpatient and outpatient departments of Obstetrics and Gynaecology at Bangabandhu Sheikh Mujib Medical University (currently, Bangladesh Medical University) Dhaka, Bangladesh for obstetric management during the study period.
Statistical analysis
All data were systematically recorded using a preformatted data collection form. Quantitative variables were presented as mean (standard deviation), while qualitative data were shown as frequencies and percentages. The chi-square test was used to assess fetal outcomes in vaginal deliveries and the repeat cesarean group. Analyses were performed using SPSS version 26 for Windows. Ethical approval was obtained from the Institutional Review Board of Bangabandhu Sheikh Mujib Medical University (currently, Bangladesh Medical University) Dhaka, Bangladesh. The procedure with benefits and risks were explained. All the patients participated voluntarily and informed written consent were taken. There was no conflict of interest. Honesty, accuracy, and freedom from bias were ensured.
Group | Didactic posttest marks (%) | Flipped posttest marks (%) | Difference in marks (mean improvement) | P |
<50% | 63.2 (9.4) | 82.2 (10.8) | 19.0 | <0.001 |
≥50% | 72.4 (14.9) | 84.2 ( 10.3) | 11.8 | <0.001 |
Data presented as mean (standard deviation) | ||||



Characteristics | Total samples (n) | Negative n (%)a | HAV infection n (%)b | HEV infection n (%)b | HAV and HEV infection n (%)b |
| 42791 | 32244 (75.3) | 5767 (29.6) | 4780 (20.5) | 85 (0.6) |
Genderc | |||||
Male | 29756 | 22369 (69.4) | 3755 (65.1) | 3632 (76.0) | 62 (72.9) |
Female | 13035 | 9875 (30.6) | 2012 (34.9) | 1148 (24.0) | 23 (27.1) |
Age (Years)c | |||||
≤10 | 7198 | 4675 (14.5) | 2183 (37.9) | 340 (7.1) | 10 (11.8) |
11-20 | 10477 | 7046 (21.9) | 2186 (37.9) | 1245 (26.0) | 41 (48.2) |
21-30 | 10828 | 7990 (24.8) | 898 (15.6) | 1940 (40.6) | 27 (31.8) |
31-40 | 5539 | 4596 (14.3) | 230 (4.0) | 713 (14.9) | 5 (5.9) |
41-50 | 3786 | 3368 (10.4) | 115 (2.0) | 303 (6.3) | 2 (2.4) |
>50 | 4963 | 4569 (14.2) | 155 (2.7) | 239 (5.0) | 0 (0) |
an= number of participants, % in bracket; bTotal samples tested for HAV infection=19452, HEV infection=23249 and both HAV & HEV infection = 13997; cPercentages for the HAV, HEV and both (HAV & HEV) infection were calculated from the total tested samples, respectively. The percentages within the group in the Gender and Age categories were calculated. | |||||
Table 1 shows that the majority of women (75.3%) were between 21–30 years of age, followed by 17.3% in the 31–40 age group, and only 7.41% were over 40. Regarding BMI, half of the participants (50%) had a normal BMI (18.5–25 kg/m²), 45.06% were overweight (BMI 26–30 kg/m²), and 4.9% were obese (BMI >30). A history of previous vaginal delivery was noted in 19.8% of women. Among those who underwent a trial of labor, 33.3% achieved a successful vaginal birth after cesarean (VBAC), while 66.7% required an emergency repeat cesarean section.
Table 1 Demographic and obstetric characteristics of study participants (n=162)
Characteristics | Number (%) |
Maternal age, years |
|
21–30 years | 122 (75.3) |
31–40 years | 28 (17.3) |
>40 years | 12 (7.4) |
Mean (Standard deviation) | 28.7 (4.8) |
Body mass index, kg/m² |
|
18.5–25 | 81 (50.0) |
26–30 | 73 (45.6) |
>30 | 8 (4.9) |
Mean (Standard deviation) | 25.1 (3.4) |
History of vaginal delivery | 32 (19.8) |
Type of delivery | |
Vaginal birth after cesarean | 54 (33.3) |
Emergency repeat cesarean section | 108 (66.7) |
As given in Table 2, the most common indication for the initial cesarean section was fetal distress (51.2%), followed by post-maturity (19.8%), breech presentation (8.0%), and transverse lie (4.3%). In emergency repeat cesarean sections, fetal distress remained the leading cause (48.2%), followed by scar tenderness (19.4%), prolonged labor (17.59%), and maternal exhaustion or personal preference (14.8%).
Table 2 Indications of caesarean sections
Characteristics | Number (%) |
First ever cesarean section |
|
Fetal distress | 83 (51.2) |
Post maturity | 32 (19.8) |
Breech presentation | 13 (8.0) |
Transverse lie | 7 (4.3) |
Prolonged labor | 8 (4.9) |
Antepartum hemorrhage | 5 (3.1) |
Elective caesarean sections (by maternal request) | 14 (8.6) |
Repeat cesarean section |
|
Fetal distress | 52 (48.2) |
Scar tenderness | 21 (19.4) |
Prolonged/failed progress of labor | 19 (17.6) |
Maternal exhaustion / own request | 16 (14.8) |
Table 3 shows that in the VBAC group (n=54), fetal distress was observed in only 3 cases (5.6%), indicating a significantly lower incidence compared to the ERCS group (n=108), where 52 cases (48.2%) experienced fetal distress (P<0.001). The fetal weight range was comparable between the two groups, with VBAC neonates weighing between 2.4–3.5 kg and ERCS neonates ranging from 2.5–3.4 kg. Assessment of Apgar scores showed that a good Apgar score (>7) was more frequently observed in the VBAC group, with 49 neonates (90.7%) scoring in the normal range, whereas only 82 neonates (75.9%) in the ERCS group had similarly favorable scores (P=0.024). Conversely, average Apgar scores (<7) were recorded in 5 neonates (9.7%) in the VBAC group and 26 neonates (24.1%) in the ERCS group (P=0.024).
Table 3 Neonatal outcomes among study participants (n=162)
Parameters | VBACa (n=54) | ERCSa (n=108) | P |
Fetal distress |
|
|
|
n (%) | 3 (5.6) | 52 (48.2) | <0.001 |
Fetal weight (kg) |
|
|
|
Range | 2.4 – 3.5 | 2.5 – 3.4 | 0.27 |
Mean (SD)a | 3.0 (0.3) | 3.0 (28.0) |
|
Apgar score at 5 min |
|
|
|
Good (>7) | 49 (90.7) | 82 (75.9) | 0.02 |
Average (<7) | 5 (9.3) | 26 (24.1) | 0.02 |
Mean (SD)a | 8.4 (0.6) | 8.0 (0.7) |
|
aVBAC indicates vaginal birth after cesarean section; ERCS, emergency repeat caesarean section; SD, standard deviation | |||
This study explored the outcome of a trial of labour after one previous caesarean section in a tertiary care hospital. It particularly focused on the clinical results and the practical realities that influence decision-making by both clinicians and patients. The findings provide a realistic view of current VBAC practice in Bangladesh, where the success of TOLAC is shaped not only by obstetric factors but also by physicians’ attitudes, patient preferences, and the readiness of the health system.
Patients’ attitudes and expectations also have a major influence on the mode of delivery. In urban areas, women often consider caesarean section a more predictable and comfortable option, while others express a strong desire for normal delivery because of faster recovery and lower cost. The decision is therefore a balance between convenience and risk perception. Proper counselling plays a vital role here. As highlighted in previous studies [14], shared decision-making that clearly explains both the benefits and risks of TOLAC can increase the rate of successful VBAC while maintaining patient safety. In our setting, patient education remains limited, and many women decide based on anecdotal experience rather than medical advice.
This study found that VBAC can be a safe and feasible option for many women, especially those with a history of vaginal delivery and favorable obstetric factors. However, failed TOLAC carries significant risks, including increased maternal morbidity. Predictive factors such as prior vaginal delivery, Bishop score, fetal weight, and maternal age should be considered when counseling women about TOLAC. Further research, particularly RCTs, is essential to refine selection criteria and improve VBAC success rates, ultimately reducing unnecessary repeat cesarean sections. Further prospective, longitudinal studies with larger sample sizes are required to improve VBAC success rates and minimise unnecessary repeat cesarean deliveries.
Concept or design of the work; or the acquisition, analysis, or interpretation of data for the work: RR, NNK, BN, TRL, FA. Drafting the work or reviewing it critically for important intellectual content: RR, NNK, BN, TRL, FA. Final approval of the version to be published: RR, NNK, BN, TRL, FA. Accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved: RR, NNK, BN, TRL, FA.



