Community Based Medical Journal https://banglajol.info/index.php/CBMJ <p>The official journal of Community Based Medical College, Mymensingh, Bangladesh. Full text articles available.</p> en-US No part of the materials published in this journal may be reproduced, stored or transmitted without prior written permission of the editorial board. cbmcbjournal95@gmail.com (Dr. Mahamud Javed Hasan) banglajol.info@gmail.com (Md Fahmid Uddin Khondoker) Wed, 17 Aug 2022 11:07:57 +0000 OJS 3.3.0.6 http://blogs.law.harvard.edu/tech/rss 60 Hodgkin’s Lymphoma: A Rare Ophthalmic Case Report https://banglajol.info/index.php/CBMJ/article/view/61287 <p>Hodgkin’s lymphoma (HL) is a disease originating from lymphoid tissues; however, it may pose a diagnostic challenge. Ocular involvement is more prevalent in non-HL compared to HL. We have reported a rare case of Hodgkin’s lymphoma presented with forwarding bulging of left eye with pain, redness, and watering. The patient also complained of painless swelling of the submandibular lymph node when admitted into the National Institute of Ophthalmology and Hospital (NIOH), Dhaka, Bangladesh; later, incision and biopsy was done at ENT &amp; Head-Neck Cancer Hospital, Dhaka, Bangladesh. Histopathology report revealed Hodgkin’s lymphoma. Hodgkin's lymphoma is a malignancy with unknown aetiology. With timely diagnosis and early treatment, our patient began to show gradual improvement with her symptoms. Prompt oncologic treatment and immunotherapy can be beneficial, if instituted early in the course of the disease.</p> <p>CBMJ 2022 July: vol. 11 no. 02 P: 158-161</p> Syeed Mehbub Ul Kadir, Tanjilla Hossain, Md Golam Haider Copyright (c) 2022 Community Based Medical Journal https://banglajol.info/index.php/CBMJ/article/view/61287 Wed, 17 Aug 2022 00:00:00 +0000 Left Ventricular Noncompaction Cardiomyopathy (LVNC): A Case Report https://banglajol.info/index.php/CBMJ/article/view/61289 <p>Left ventricular noncompaction is a rare congenital cardiomyopathy. It can occur in isolation or coexist with other cardiac anomalies. Clinical presentation varies from patients to patients. LVNC is commonly diagnosed by echocardiography. We descried the case of a man with heart failure for the first time at 55 years of age. Transthoracic echocardiography shows trabeculation and intertrabecular recesses communicate with the ventricle cavity. The patient was relatively well after medical management. This case is reported for clinical awareness and share experience.</p> <p>CBMJ 2022 July: vol. 11 no. 02 P: 162-166</p> Tofayel Uddin Ahmed, Amdadul Haque, Parvez Rahman Khan Copyright (c) 2022 Community Based Medical Journal https://banglajol.info/index.php/CBMJ/article/view/61289 Wed, 17 Aug 2022 00:00:00 +0000 Serum Zinc Level in Children Suffering from Type 1 Diabetes Mellitus and Its Relationship with Glycemic Control: An Experience from A Tertiary Level Specialized Diabetic Hospital in Bangladesh https://banglajol.info/index.php/CBMJ/article/view/61223 <p>A cross-sectional study was conducted in the Department of Biochemistry and Molecular Biology of Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM), Dhaka, Bangladesh, between July 2016 and June 2017, to evaluate serum zinc level and its relationship with glycemic control in type 1 diabetic children. A total of 160 participants (all aged between 1 and 18 years) were selected from the outpatient department (OPD) of BIRDEM General Hospital-2, Dhaka – 80 type 1 diabetic children as cases and 80 apparently healthy children as controls. We measured anthropometric parameters all study subjects. Serum zinc level was assessed using colorimetric method. Fasting plasma glucose level was estimated using enzymatic glucose-oxidase method. Glycemic control was evaluated through estimation of HbA1c using a high-performance liquid chromatographic method. The mean serum zinc levels were significantly lower in patient with type 1 DM compared to control (72.5±16.5 vs. 82.4±13.3 μg/dl; P&lt;0.001). Lower levels of zinc were found in subjects with poor glycemic control compared to good glycemic control (62.8±14.6 vs. 78.8±14.6 μg/dl; P&lt;0.001). Moreover, serum zinc levels were significantly lower in patients who have duration of diabetes mellitus for 5 years or more (P&lt;0.05). To summarize, serum zinc level is lower in type 1 diabetic children in comparison to its healthy counterpart and this lower zinc level is strongly associated with poor glycemic control which may potentially contribute to the early development of diabetic complications in children.</p> <p>CBMJ 2022 July: vol. 11 no. 02 P: 80-85</p> Shawana Haque, Miliva Mozaffor, Md Mostaque Mahmud, MA Muttalib Copyright (c) 2022 Community Based Medical Journal https://banglajol.info/index.php/CBMJ/article/view/61223 Wed, 17 Aug 2022 00:00:00 +0000 Effectiveness of Erector Spinae Plane Block for Postoperative Analgesia in Modified Radical Mastectomy https://banglajol.info/index.php/CBMJ/article/view/61224 <p>Postoperative pain control in breast cancer surgery has become one of the most important goals for anesthesiologists. Several techniques have been trialed for providing postoperative analgesia after breast surgery. This randomized control study was designed to evaluate the postoperative analgesic effect of ultrasound-guided erector spinae plane (US-guided ESP) block for modified radical mastectomy surgery. To evaluate the postoperative analgesic effect of pectoral nerves block and erector spinae plane block for modified radical mastectomy surgery. This prospective, randomized, controlled trial was conducted at the Department of Anaesthesia, Analgesia, Palliative &amp; Intensive Care Medicine in Dhaka Medical College and Hospital. A total 46 patients who were to undergo modified radical mastectomy, fulfilling selection criteria were included in the study following confirmation of the informed written consent and randomly divided into two groups- where each group include 23 Patients. Group A received ultrasound guided ESP and group B received ultrasound guided PECS block. All patients of both groups received GA after confirmation of block. All relevant information including demographic criteria, medical history, clinical evaluation during and after performance of block were collected. All patients were observed peri-operatively and data were recorded into the preformed questionnaires form. Finally, data was analyzed by SPSS version 22.0. Mean age of study population was 52.07±7.08 years with majority in age group 50-59 years. No significant difference was noted between patient’s characteristics, duration of surgery and heart rate and mean arterial pressure of patient during and after operation between two groups (p&gt;0.05). The mean VAS score was significantly low in ESP block as compared to the PECS block at all-time interval (p&lt;0.05) except at 12 hours. Patients with ESP block had significantly late demand of 1st analgesic (12.13±2.45 hours vs 8.89±3.35 hours) (p&lt;0.05) and significantly less total opioid consumption (5.17±0.57 mg vs 10.18±1.82 mg) (p&lt;0.05) compared to patients with PECS block. Post-operative complication was noted significantly higher among patients with PECS block compared to ESP block. These findings from our study depict ESP block performed in patients scheduled for MRM (modified radical mastectomy) results in better pain control and less postoperative opioid consumption in the first 24 hours than PECS block.</p> <p>CBMJ 2022 July: vol. 11 no. 02 P: 86-95</p> Md Humayun Kabir, Mohammad Mahabubuzzaman, Lipon Kanti Bhowmick, Md Saiful Islam, Md Ruhul Amin, Md Abdur Rahim Copyright (c) 2022 Community Based Medical Journal https://banglajol.info/index.php/CBMJ/article/view/61224 Wed, 17 Aug 2022 00:00:00 +0000 Potential Attenuating Effect of Single Bolus Dose of Esmolol on Cardiovascular Stress Response in Elective Neurosurgical Cases https://banglajol.info/index.php/CBMJ/article/view/61225 <p>A prospective, double blind and randomized study was conducted in the Department of Anesthesiology of Dhaka Medical College Hospital, Dhaka, Bangladesh, between January 2013 and January 2014, to assess the efficacy of single bolus dose of esmolol (1.5mg/kg) to attenuate the cardiovascular stress response in elective neurosurgical cases. A total of 100 elective neurosurgical patients were enrolled in this study. Patients were randomly allocated equally into two groups: group A and group B, having 50 patients in each group. Patients of group A received intravenous esmolol (1.5mg/kg), 3 minutes before induction, while patients of group B received intravenous 10 ml of normal saline 3 minutes before induction. Parameters like heart rate, systolic and diastolic blood pressure were recorded before induction and every alternative minute for 10 minutes after endotracheal intubation. There were no differences in baseline demography of the patients (P&gt;0.05). However, our data showed that in group A, there were significant reductions in heart rates immediately after induction, 1 minute, 3 minutes and 5 minutes after endotracheal intubation (P&lt;0.01), as well as significant reductions in systolic and diastolic blood pressure after 1 minute, 3 minutes and 5 minutes of endotracheal intubation (P&lt;0.01) respectively, in comparison to group B. Besides, reductions in rate pressure product were observed immediately after induction and 1 minute, 3 minutes and 5 minutes after endotracheal intubation respectively in group A, as compared to group B (P&lt;0.01). In summary, a single bolus dose of esmolol (1.5mg/kg) effectively attenuates the cardiovascular stress response during and after laryngoscopy and endotracheal intubation in elective neurosurgical cases.</p> <p>CBMJ 2022 July: vol. 11 no. 02 P: 96-101</p> Md Zahedul Islam, Suraya Akter, Shahid Kamal Copyright (c) 2022 Community Based Medical Journal https://banglajol.info/index.php/CBMJ/article/view/61225 Wed, 17 Aug 2022 00:00:00 +0000 Position and Attachment of the Babies During Breastfeeding: A Comparison of Before and After Counselling the Mothers https://banglajol.info/index.php/CBMJ/article/view/61226 <p>A prospective, observational study was conducted in the Department of Obstetrics &amp; Gynaecology of Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh, between July 2008 and January 2009 to compare position and attachment of the babies during breastfeeding before and after counselling the mothers. Our study samples include 100 healthy mothers and 100 term healthy babies. Initially, all the mothers and babies were observed for their position and attachment during breastfeeding within 24 hours of the delivery and documented in a standard data sheet. Then the mothers were shown the wall chart of nursing mothers and breastfeeding manual and taught practically by the investigators. Mothers were requested to come after 15 days for follow-up visit so that they become physically fit by that time and improve their skills. At follow-up visit, documentation of the position and attachment during breastfeeding was done in the data sheet. Comparison of each of the components of positioning and attachment was done with first observation (i.e., within 24 hours of the birth of the baby) and follow-up observation (i.e., after 15 days). The mean age of the mothers was 29.40±4.71 years. In all components of the position and attachment of the babies, the difference between before and after counselling the mothers was statistically significant (P&lt;0.05). Similarly, in all signs of effective sucking, the difference was also statistically significant between before and after counselling (P&lt;0.05) except for the sign of oxytocin reflex noticed by the mother (P&gt;0.05).</p> <p>CBMJ 2022 July: vol. 11 no. 02 P: 102-107</p> Shamsi Sumaiya Ashique, Ainun Afroze, Rubina Afroz Rana, Habiba Jesmin, Shabnam Sharmin, Saida Sharmin Copyright (c) 2022 Community Based Medical Journal https://banglajol.info/index.php/CBMJ/article/view/61226 Wed, 17 Aug 2022 00:00:00 +0000 Pattern of Clinicopathological Features of Head and Neck Cancer Patients in a Tertiary Level Specialized Hospital in Dhaka, Bangladesh https://banglajol.info/index.php/CBMJ/article/view/61227 <p>A cross-sectional, descriptive study was conducted to see the pattern of clinicopathological features of head and neck cancer patients in a tertiary level hospital. The study was conducted between January and April of 2017 in National Institute of Cancer Research &amp; Hospital (NICRH), Dhaka, Bangladesh. Data was collected from a total number of 69 histopathologically and clinically confirmed patients. A male predominance (2.14:1) was noted except for oral cavity cancer (1:1). Mean age for males and females were (56.15±11.47) years and (54.50±7.16) years respectively. Positive history of associated factors like smoking (60.34%), betel nut and betel leaf (81.36%), smokeless tobacco (56.90%) was prevalent among majority of the participants except for alcohol (6.90%). Smoking was prevalent only among males. Knowledge regarding the role of associated factors was very poor, e.g., smoking (10.61%), betel nut &amp; leaf (7.58%), smokeless tobacco (6.06%), alcohol (7.58%) for causing cancer. 10.71% patients gave positive family history of cancer (1st degree relative). 27.59% patients gave history of treatment by homeopathy/traditional healers. The most common sites of cancer in males were larynx (27.3%) followed by oral cavity (20.5%). In case of female patients, most common sites were oral cavity (40.9%) followed by larynx (22.7%). Most common histopathological type was squamous cell carcinoma (91.94%). Lymph node metastasis were present in 47.62% patients, whereas only 1.56% patients had distant metastasis and 3.13% had recurrent/residual disease. 18.64% patients gave history of definitive surgery. To conclude, most of the patients usually reported with advanced stages of cancer; however, preventable factors were found among all of them. Unfortunately, they had very poor knowledge about those preventable factors which warrants an immediate and elaborate public health program to fill up this vast gap of knowledge. Prevention and early diagnosis should be main arsenal to combat head and neck cancer.</p> <p>CBMJ 2022 July: vol. 11 no. 02 P: 108-113</p> Md Rakibul Islam Masud, Mojibur Rahman Khan, Md Jahin Tareq Bhuiyan, Badrun Nahar Tuly, Mohammad Saiful Islam Pathan Copyright (c) 2022 Community Based Medical Journal https://banglajol.info/index.php/CBMJ/article/view/61227 Wed, 17 Aug 2022 00:00:00 +0000 Meconium-Stained Amniotic Fluid and Its Perinatal Feto-maternal Outcome https://banglajol.info/index.php/CBMJ/article/view/61228 <p>Meconium Stained Amniotic Fluid is associated with increased risk of operative delivery or caesarean section and increased rate of neonatal resuscitation, morbidity and mortality. A hospital-based prospective, observational study was conducted in the Obstetrics &amp; Gynecology Department, NICU and Neonatal Ward of Naval Base Hospital, a tertiary care hospital of Bangladesh Navy, Chattogram, Bangladesh, between January 2020 and December 2021. A semi-structured questionnaire was prepared for both case and control group. 182 cases were enrolled as case and another 182 cases were as control. Antenatal checkup was significantly less in cases (p&lt;0.05). Mean weight was 2.8±0.4 Kg in cases and in control 2.7±0.5 Kg (p&lt;0.01). Mean fetal heart rate were 140±10.5 beats/min in cases and in control 135.7±7.2 beats/min (p&lt;0.01). Apgar scores at 1st minute and fifth minutes were significantly lower in cases (7±1.4 and 8.2±1.2 respectively) in comparison to control (7.5±0.3 and 9.2±1.1 respectively). Obstetric outcome of labor, that is mode of delivery was significantly dictated by the presence of MSAF. There were more than half (57.1%) of the cases were having grade three MSAF, whereas grade one and grade two were 14.8% and 28% respectively. Perinatal asphyxia, 5 min APGAR score &lt;7, oropharyngeal suction needed, EONS, MAS, admission in NICU/Neonatal ward and neonatal death all were significantly higher in MASF group. MSAF is associated with increased need for neonatal resuscitation, higher risk of perinatal asphyxia, MAS, hospital admission and mortality for fetus and higher risk for operative delivery.</p> <p>CBMJ 2022 July: vol. 11 no. 02 P: 114-119</p> Md Mahbubur Rahman, Abdullah Al Amin, Md Abdul Quader Copyright (c) 2022 Community Based Medical Journal https://banglajol.info/index.php/CBMJ/article/view/61228 Wed, 17 Aug 2022 00:00:00 +0000 Visual Outcome after Cataract Surgery in Phacolytic Glaucoma https://banglajol.info/index.php/CBMJ/article/view/61229 <p>A prospective study was conducted between March 2021 and February 2022 in the National Institute of Ophthalmology &amp; Hospital, Dhaka, Bangladesh involving 30 patients who underwent cataract surgery for phacolytic glaucoma. The aim of this study was to see the postoperative visual outcome of cataract surgery in patients with phacolytic glaucoma. Visual acuity and development of any postoperative complications were recorded. The mean age of the patients was 60.7 years. Female to male ratio was 1.3:1. Most of the patients (67%) presented after 1 week of symptoms. On the first visit, mean preoperative intraocular pressure (IOP) was 37.5 mm of Hg. Following surgery, 93.33% had an intraocular pressure less than 21 mm Hg at discharge. Visual acuity (VA) as perception of light (PL) was found doubtful in 2 (6.67%), while PL was positive in 17 (56.66%) and HM &lt;3/60 was in 11 (36.66%) preoperatively. At discharge, 73.33% achieved VA 6/24 or better, 5 (16.67%) had less than 6/24 and 3 (10%) less than 3/60. Cataract surgery is effective to restore visual acuity and lowering the intraocular pressure (IOP) in patients with phacolytic glaucoma.</p> <p>CBMJ 2022 July: vol. 11 no. 02 P: 120-124</p> Mohammad Ariful Islam, Mohammad Ghulam Rasul, SM Enam ul Haque, Faisal Quader Shah Chowdhury, Afroza E Alam, Mohammad Farid Hossain, Mohammad Rashedul Hasan, Polash Kanti Mistry Copyright (c) 2022 Community Based Medical Journal https://banglajol.info/index.php/CBMJ/article/view/61229 Wed, 17 Aug 2022 00:00:00 +0000 Common Health Problems Among Agricultural Workers in A Selected Rural Area of Mymensingh, Bangladesh https://banglajol.info/index.php/CBMJ/article/view/61230 <p>This cross-sectional descriptive study was conducted in Churkhai village of Bhavokhali union during December 2018 to find out common health problems among 200 agricultural workers in a selected rural area of Mymensingh as a part of Residential Field Site Training by 3rd year MBBS students session 2016-17. 63 percent of population lives in rural area. Agricultural workers have illnesses common to general population. Moreover socioeconomic and work condition poses extra burden. The study was carried out on 200 agricultural workers who were selected purposively. Data were collected on a predesigned questionnaire by face to face interviewing agricultural workers. Data analysis was done by SPSS version 20.0. Age distribution of respondents ranged from 19 years to 80 years; mean age 46.53 years and standard deviation 14.891 years. Males were predominant (male: female ratio 506.06: 100. Majority of them (57.50%) were literate. Most of them (65.00%) belonged to middle class family. More than half (55.00%) of agricultural workers were suffering from illness. Respiratory illnesses 16.00% were predominant followed by skin disease 10.50%, gastrointestinal disease 6.50%, conjunctivitis 6.00%, arthritis 6.00%, hypertension 6.00%, diabetes mellitus 5.00%, anemia 4.50% and hearing loss 0.50%. In summer heat exhaustion (14.50%) was predominant followed by heat syncope (10.00%. In rainy season ARI (12.00%) was predominant followed by diarrheal diseases (10.50%). In winter mild hypothermia (27.00%) was predominant followed by ARI (4.50%). In recall of last 1 year the important events were crop loss 12.50%, damage to house 10.00%, and unemployment 2.50%. There was no case of anthrax and bird flu. Prevalence of occupational accidents was 5.00%. which includes fall from height 0.50%, heavy object fallen on body 1%, domestic fire 1%, electrocution in house 1%, electrocution by power pump 0.50%, cattle hitting by horn 0.50% and accidental insecticide poisoning 0.5%. Most of the injury occurred in the current week. Majority of the workers (66.50%) had partial tetanus toxoid immunization. Morbidity in this study was better than several studies conducted in Bangladesh and India. By knowing health problems we can give health care to agricultural workers which will prevent diseases and illnesses of them, prolong their healthy life, promote their health and efficiency.</p> <p>CBMJ 2022 July: vol. 11 no. 02 P: 125-130</p> AHM Hasan, Md Tufael Hossain, Maksuda Begum, Md Shahidul Islam, Fakir Sameul Alam Copyright (c) 2022 Community Based Medical Journal https://banglajol.info/index.php/CBMJ/article/view/61230 Wed, 17 Aug 2022 00:00:00 +0000 Measurement of the Breadth of the Thyroid Lamina in A Bangladeshi Population by Dissection Method https://banglajol.info/index.php/CBMJ/article/view/61282 <p>A cross-sectional, descriptive study was done to determine the breath of the thyroid lamina and the differences in its values in respect of age and sex in Bangladeshi cadavers. A total 60 postmortem human larynges were collected between October 2008 and March 2009. Among those, 45 (male 23 and female 22) were collected from unknown dead bodies (aged between 9 and 60 years) under autopsy in the mortuary of Department of Forensic Medicine of Mymensingh Medical College, while the other 15 (male 6 and female 9) were collected from stillborn babies of viable age (28 to 40 weeks of gestation) in the Department of Obstetrics &amp; Gynaecology of Mymensingh Medical College Hospital, Mymensingh, Bangladesh. The breath of thyroid lamina was measured from laryngeal prominence to the posterior margins of lamina at its transverse plane using slide calipers and differences were observed in between age groups and sexes. The mean±SD breadth of thyroid lamina was found 12.40±1.30 mm in group A (from 28 to 40 weeks of gestation) ranging between 9 and 14 mm, while 26.19±3.69 mm in group B (from 9 to 16 years) ranging between 21 and 35 mm, and 30.76±4.17 mm in group C (from 17 to 60 years) with a range of 24 to 38 mm. The mean breadth of thyroid lamina was highest in age group C (30.76 mm) and was lowest in age group A (12.40 mm). The mean difference of breadth of thyroid lamina between group A &amp; B, A &amp; C and B &amp; C were statistically significant (P=0.000). The breadth of thyroid lamina was found higher in male (32.70±3.96 mm) than that of female (28.00±2.69 mm) in Group C and the difference was statistically significant (p=0.001). Our study revealed that the breadth of thyroid lamina is greater in adult male than female and overall, the value increases with age.</p> <p>CBMJ 2022 July: vol. 11 no. 02 P: 131-135</p> Anjuman Ara, Zubaida Gulshan Ara, Taslima Begum, Dilruba Afrose Mili, Kamrun Naher Copyright (c) 2022 Community Based Medical Journal https://banglajol.info/index.php/CBMJ/article/view/61282 Wed, 17 Aug 2022 00:00:00 +0000 Knowledge and Practice of Personal Hygiene Among the High School Students in A Rural Area of Mymensingh, Bangladesh https://banglajol.info/index.php/CBMJ/article/view/61283 <p>This cross-sectional descriptive study was conducted during November 2019 to assess knowledge and practice of personal hygiene among the high school students in a rural area of Mymensingh. Proper knowledge and practice of personal hygiene plays critical role in avoiding communicable diseases and benefit the high school students to enjoy healthy life with excellent academic career. Respondents were 244 high school students of different schools in Churkhai, Bhavokhali, Mymensingh who were selected purposively. Age ranged from 10 years to 17 years, mean age 13.32 years with SD ± 1.505 years; boys predominant (boy: girl ratio 146.5: 100). Data were collected on a predesigned questionnaire by direct interviewing the students. Knowledge and practice of personal hygiene were measured using scoring based on correct answers. Data analysis was done by SPSS version 20.0. Most of them (217) 88.93% were apparently healthy. Based on presenting symptoms and signs the diagnosed illnesses were ARI (7) 2.87%, diarrhea (5) 2.05%, head lice (5) 2.05%, scabies (4) 1.64%, injury (3) 1.23%, dental caries (2) 0.82% and peptic ulcer disease (1) 0.41%. Important personal hygiene practices inquired were frequency of regular bathing with use of soap or shampoo, combing hair, brushing teeth, hand washing, trimming nails, wearing shoes, clean clothes, avoidance of smoking and appropriate allocation of time for study, outdoor, indoor activities, rest and sleep. Based on aggregate items 80.74% had excellent knowledge and practice on personal hygiene and 19.26% had good knowledge and practice. Knowledge and practice were concordant in all elements inquired except smoking. Knowledge about harm of smoking was 100.00% though avoidance of smoking was 97.95%. Knowledge and practice scores were influenced by educational grade (class VIII at peak), literate parents, better socioeconomic condition and absence of illness. The results are better than the findings of studies conducted in our country and neighboring countries.</p> <p>CBMJ 2022 July: vol. 11 no. 02 P: 136-143</p> Maksuda Begum, Fakir Sameul Alam, Md Tufael Hossain, AHM Hasan Copyright (c) 2022 Community Based Medical Journal https://banglajol.info/index.php/CBMJ/article/view/61283 Wed, 17 Aug 2022 00:00:00 +0000 Dermatoglyphic Assessment in Male Down Syndrome https://banglajol.info/index.php/CBMJ/article/view/61284 <p>Down syndrome (DS) is the most common chromosomal disorder which causes intellectual disability. It is mainly because of the presence of extra copy of chromosome number 21. Dermatoglyphic has been well established as a diagnostic aid in number of diseases having hereditary basis. Dermatoglyphic data was obtained by the use of ink and prints on a paper. This cross-sectional, analytical type of study was performed at the Department of Anatomy, Dhaka Medical College, Dhaka from January 2017 to December 2017 on 40 Down syndrome subjects (age ranged from 6 to 16) selected from Society for the Welfare of the Intellectually Disabled, Bangladesh (SWID, Bangladesh) and Down Syndrome Society of Bangladesh (DSS) and compared with 40 controls for the establishment of comparison between two groups. Dermatoglyphic prints were used to evaluate the difference in „atd‟ „dat‟ „adt‟ angles and pattern intensity between the control and the DS individuals. The results showed that „atd‟ angle was significantly higher (p&lt;0.05) in Down males than the controls. The dactylography study also revealed lower „dat‟ „adt‟ angles (p&lt;0.05) and pattern intensity (p&lt;0.001) in both hands of Down syndrome group. This method is non-invasive and cost effective. The observed changes in the „atd‟ „dat‟ and „adt‟ angles plus the patterns intensity in the dermatoglyphic study proved that this simple technique could be a valuable tool for selecting individuals of DS for cytogenetic analysis.</p> <p>CBMJ 2022 July: vol. 11 no. 02 P: 144-151</p> Rehana Parveen, Md Shamsur Rahman, Mahmuda Ahmed, Md Ashraful Azim, Zeenatul Momena, Mohammad Nahid Salman Copyright (c) 2022 Community Based Medical Journal https://banglajol.info/index.php/CBMJ/article/view/61284 Wed, 17 Aug 2022 00:00:00 +0000 Correlation between Sociodemographic Variables and OncoE6 Cervical Swab Test Positive Cases https://banglajol.info/index.php/CBMJ/article/view/61285 <p>A cross-sectional, observational study was conducted to determine the relationship between sociodemographic variables and the development of cervical cancer through detection of detection of HPVE6 oncoprotein. A total of 47 endocervical swabs were collected from colposcopy clinic under the Department of Obstetrics &amp; Gynaecology, Mymensingh Medical College, Mymensingh, Bangladesh, from January to December of 2015. Laboratory work was done in the Department of Microbiology of the same institution. E6 strip test is an immunochromatographic test based on detection of HPV-E6 oncoprotein in cervical swab samples. The swab specimen was treated with lysis solution and conditioning solution. Then the specimen solution was clarified by centrifugation. After that the sample solution was transferred into the detector mAb vial, wash solution vial, and finally, into developing solution vial. The test unit was then placed on a reading guide. Positive result was indicated by the appearance of purple colored test line. Out of 47 specimens, 21 (44.68%) were OncoE6 positive. Among those 21 positive cases, 19 (90.48%) were HPV-16 and 2 were (9.52%) HPV-18. Out of 11 histologically diagnosed CIN I cases, 1 (9.09%) case came out as positive. However, there were no positive cases by oncoE6 cervical swab test in CIN II and CINIII categories. Among histopathologically confirmed 22 cervical carcinoma cases, 20 (90.90%) came out as positive through this test. The results were compared with sociodemographic variables. OncoE6 is more common among ≥50 age group, and who got married before 18 years, and in multiparous women (P&lt;0.05). Cervical cancer prevention services should be strengthen including health education, OncoE6 screening, and Anti-HPV vaccination.</p> <p>CBMJ 2022 July: vol. 11 no. 02 P: 152-157</p> Faijun Nahar, Md Akram Hossain, Shyamal Kumar Paul, Sufia Khatun, Golam Rahman Bhuiyan, Syeda Anjuman Nasreen, Salma Ahmed, Nazia Haque Copyright (c) 2022 Community Based Medical Journal https://banglajol.info/index.php/CBMJ/article/view/61285 Wed, 17 Aug 2022 00:00:00 +0000 Novel Agents to Treat Renal Anemic Patient https://banglajol.info/index.php/CBMJ/article/view/61222 <p>Abstract not available</p> <p>CBMJ 2022 July: vol. 11 no. 02 P: 77-79</p> Mahmud Javed Hasan Copyright (c) 2022 Community Based Medical Journal https://banglajol.info/index.php/CBMJ/article/view/61222 Wed, 17 Aug 2022 00:00:00 +0000 Teaching and Learning Medical Ethics: How to Bring Positive Change https://banglajol.info/index.php/CBMJ/article/view/61290 <p>Decision making in healthcare does not depend only on mastery of knowledge, clinical skills, and technical competencies, rather it is largely influenced by ethical competences of the physicians. Teaching medical ethics in undergraduate medical education (MBBS programme in Bangladesh) helps medical students recognize the importance of being sensitive to ethical issues within everyday clinical practice and develop in them the ability to effectively address the concerns of patients and families, as well as participants in health research and larger society. In medical practice, its ethical component is treated as an obligatory one, no matter what the specialty is. The importance of ethics in medicine is increasing greatly day by day; its dimensions are also changing. In this review paper, we have tried to discuss some effective changes in medical ethics curriculum, methods of teaching and learning, faculty development, and institutional culture. All stakeholders should think about it and take necessary actions into that direction, which will ultimately lead to building a more ethical, more patient-centred, more professional medical community in the country.</p> <p>CBMJ 2022 July: vol. 11 no. 02 P: 167-175</p> Abu Sadat Mohammad Nurunnabi, Mahmud Javed Hasan, ASM Ruhul Quddus, Md Tariqul Islam Khan, Mohammad Tipu Sultan, Saida Sharmin, Md Mahfuzur Rahman, Kaminee Kumar Tripura, Sadia Nusrat Alamgir Copyright (c) 2022 Community Based Medical Journal https://banglajol.info/index.php/CBMJ/article/view/61290 Wed, 17 Aug 2022 00:00:00 +0000