Treatment Related Factors Associated with Non-adherence to Anti-Tuberculosis Treatment

Authors

  • Md Motahar Hossain MOIC, Medical Store, Combined Military Hospital, Dhaka, Bangladesh
  • Meerjady Sabrina Flora Director, Institute of Epidemiology, Disease Control and Research (IEDCR), Mohakhali, Dhaka, Bangladesh
  • Md Saydur Rahman Contingent Commander, BANMED-2/1, Central Africa, MINUSCA
  • Md Nurul Amin Addl DG, Border Guard Bangladesh, Dhaka, Bangladesh
  • Murshida Mosharref Classified Specialist in Paediatrics, CMH, Dhaka, Bangladesh
  • Farzana Zafreen Professor & Head, Department of Community Medicine, Medical College for Women & Hospital, Uttara, Dhaka, Bangladesh

DOI:

https://doi.org/10.3329/dmcj.v9i2.74873

Keywords:

Tuberculosis, Adherence, Anti-TB treatment

Abstract

Background: Non-adherence to anti-tuberculosis treatment may result in persistent infectiousness on the part of the patient and a higher rate of treatment failure, relapse and drug resistance and therefore, is a significant barrier to the success in tuberculosis control.

Objective: To determine the treatment related factors associated with non-adherence to anti-tuberculosis treatment among tuberculosis patients. Materials and method: This case control study was carried out among purposively selected 47
tuberculosis patients non-adherent to treatment (cases) and 94 tuberculosis patients adherent to treatment (controls) and were interviewed with a semi-structured questionnaire and checklist in selected DOTS centres of Dhaka city.

Results: Statistical analysis shows that, factors like delay in seeking tuberculosis treatment for >6 weeks (OR=4.57; 95% CI, 1.48-14.1) and getting medicine weekly once (OR=2.8; 95% CI, 1.13-6.77) were more likely to be associated with non-adherence to treatment. Less
frequent visit by health providers (p=0.02), no support for side effect (p=0.042) and non-observation of medication (p=0.009) were also found significant. The reasons behind missing anti-TB doses among non-adherent cases were due to feeling better (53.2%), personal reason (25.5%), feeling worse (19.1%) and forgot to take medicine (2.2%).

Conclusion: Mass awareness among the tuberculosis patients is required to improve attitude towards anti-tuberculosis treatment and activities of tuberculosis control programme require further strengthening especially in targeting the patients of low economic status.

Delta Med Col J. Jan 2021;9(2): 96-100   

Downloads

Download data is not yet available.
Abstract
86
PDF
76

Downloads

Published

2024-07-14

How to Cite

Hossain, M. M., Flora, M. S., Rahman, M. S., Amin, M. N., Mosharref, M., & Zafreen, F. (2024). Treatment Related Factors Associated with Non-adherence to Anti-Tuberculosis Treatment. Delta Medical College Journal, 9(2), 96–100. https://doi.org/10.3329/dmcj.v9i2.74873

Issue

Vol. 9 No. 2 (2021)

Section

Original Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Copyright on any research article is transferred in full to Delta Medical College Journal upon publication in the journal. The copyright transfer includes the right to reproduce and distribute the article in any form of reproduction (printing, electronic media or any other form).

Creative Commons Licence
Articles in the Delta Medical College Journal are Open Access articles published under a Creative Commons Attribution 4.0 International License CC BY License.

This license permits use, distribution and reproduction in any medium, provided the original work is properly cited.