Treatment Related Factors Associated with Non-adherence to Anti-Tuberculosis Treatment

Authors

  • Md Motahar Hossain MOIC, Medical Store, Combined Military Hospital, Dhaka, Bangladesh
  • Meerjady Sabrina Flora Director, Institute of Epidemiology, Disease Control and Research (IEDCR), Mohakhali, Dhaka, Bangladesh
  • Md Saydur Rahman Contingent Commander, BANMED-2/1, Central Africa, MINUSCA
  • Md Nurul Amin Addl DG, Border Guard Bangladesh, Dhaka, Bangladesh
  • Murshida Mosharref Classified Specialist in Paediatrics, CMH, Dhaka, Bangladesh
  • Farzana Zafreen Professor & Head, Department of Community Medicine, Medical College for Women & Hospital, Uttara, Dhaka, Bangladesh

DOI:

https://doi.org/10.3329/dmcj.v9i2.74873

Keywords:

Tuberculosis, Adherence, Anti-TB treatment

Abstract

Background: Non-adherence to anti-tuberculosis treatment may result in persistent infectiousness on the part of the patient and a higher rate of treatment failure, relapse and drug resistance and therefore, is a significant barrier to the success in tuberculosis control.

Objective: To determine the treatment related factors associated with non-adherence to anti-tuberculosis treatment among tuberculosis patients. Materials and method: This case control study was carried out among purposively selected 47
tuberculosis patients non-adherent to treatment (cases) and 94 tuberculosis patients adherent to treatment (controls) and were interviewed with a semi-structured questionnaire and checklist in selected DOTS centres of Dhaka city.

Results: Statistical analysis shows that, factors like delay in seeking tuberculosis treatment for >6 weeks (OR=4.57; 95% CI, 1.48-14.1) and getting medicine weekly once (OR=2.8; 95% CI, 1.13-6.77) were more likely to be associated with non-adherence to treatment. Less
frequent visit by health providers (p=0.02), no support for side effect (p=0.042) and non-observation of medication (p=0.009) were also found significant. The reasons behind missing anti-TB doses among non-adherent cases were due to feeling better (53.2%), personal reason (25.5%), feeling worse (19.1%) and forgot to take medicine (2.2%).

Conclusion: Mass awareness among the tuberculosis patients is required to improve attitude towards anti-tuberculosis treatment and activities of tuberculosis control programme require further strengthening especially in targeting the patients of low economic status.

Delta Med Col J. Jan 2021;9(2): 96-100   

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Published

2024-07-14

How to Cite

Hossain, M. M., Flora, M. S., Rahman, M. S., Amin, M. N., Mosharref, M., & Zafreen, F. (2024). Treatment Related Factors Associated with Non-adherence to Anti-Tuberculosis Treatment. Delta Medical College Journal, 9(2), 96–100. https://doi.org/10.3329/dmcj.v9i2.74873

Issue

Vol. 9 No. 2 (2021)

Section

Original Articles

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