Neoandrographolide Isolated from Leaves of <i>Adhatoda vasica</i> Nees

Authors

  • MD Al-Amin Department of Applied Chemistry and Chemical Engineering, Dhaka University, Dhaka
  • Md Monirul Islam Department of Applied Chemistry and Chemical Engineering, Dhaka University, Dhaka
  • M Mahboob Ali Siddiqi Institute of Natural Sciences,United International University, Dhaka
  • Shakila Akter Analytical Research Division, Bangladesh Council of Scientific and Industrial Research, Dhaka
  • Shamim Ahmed Analytical Research Division, Bangladesh Council of Scientific and Industrial Research, Dhaka
  • Mohammad Majedul Haque Analytical Research Division, Bangladesh Council of Scientific and Industrial Research, Dhaka
  • Nasim Sultana Analytical Research Division, Bangladesh Council of Scientific and Industrial Research, Dhaka
  • AM Sarwaruddin Chowdhury Department of Applied Chemistry and Chemical Engineering, Dhaka University, Dhaka

DOI:

https://doi.org/10.3329/dujs.v60i1.10326

Keywords:

Adhatoda vasica, Acanthaceae, Neoandrographolide, Brine shrimp lethality bioassay, antimicrobial screening

Abstract

Neoandrographolide was isolated from the ethylacetate soluble fraction of the ethanol extract of the fresh leaves of Adhatoda vasica (Family: Acanthaceae). The crude extracts of hexane, ethylacetate and butanol soluble fractions of ethanol extract were subjected to antimicrobial screening and brine shrimp lethality bioassay. The ethylacetate crude extract exhibited moderate antimicrobial activity against most of the test organisms and also showed significant cytotoxicity having LC50 0.61 µg/ml.

DOI: http://dx.doi.org/10.3329/dujs.v60i1.10326

Dhaka Univ. J. Sci. 60(1): 1-3, 2012 (January)

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Published

2012-04-14

How to Cite

Al-Amin, M., Islam, M. M., Siddiqi, M. M. A., Akter, S., Ahmed, S., Haque, M. M., Sultana, N., & Chowdhury, A. S. (2012). Neoandrographolide Isolated from Leaves of <i>Adhatoda vasica</i> Nees. Dhaka University Journal of Science, 60(1), 1–3. https://doi.org/10.3329/dujs.v60i1.10326

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