Isolation of Quercetin-3-O-beta-d-glucopyranoside from the Leaves of <i>Azadirachta Indica</i> and Antimicrobial and Cytotoxic screening of the Crude Extracts

Authors

  • Monirul Islam Department of Applied Chemistry and Chemical Engineering,Dhaka University, Dhaka
  • MD Al-Amin Department of Applied Chemistry and Chemical Engineering,Dhaka University, Dhaka
  • M Mahboob Ali Siddiqi Department of Applied Chemistry and Chemical Engineering,Dhaka University, Dhaka
  • Shakila Akter Analytical Research Division, Bangladesh Council of Scientific and Industrial Research, Dhaka
  • Mohammad Majedul Haque Analytical Research Division, Bangladesh Council of Scientific and Industrial Research, Dhaka
  • Nasim Sultana Analytical Research Division, Bangladesh Council of Scientific and Industrial Research, Dhaka-
  • AM Sarwaruddin Chowdhury Analytical Research Division, Bangladesh Council of Scientific and Industrial Research, Dhaka

DOI:

https://doi.org/10.3329/dujs.v60i1.10328

Keywords:

Azadirachta indica, Meliaceae, Quercetin-3-O-beta-D-glucopyranoside, Brine shrimp lethality bioassay, antimicrobial screening

Abstract

Quercetin-3-O-beta-D-glucopyranoside was isolated from the ethylacetate soluble fraction of the ethanol extract of the fresh leaves of Azadirachta indica (Family: Meliaceae). The crude extract of hexane, ethylacetate and butanol soluble fractions of this ethanol extract were subjected to antimicrobial screening and brine shrimp lethality bioassay. The ethylacetate crude extract exhibited moderate antimicrobial activity against most of the test organisms and also showed significant cytotoxicity having LC50 0.61 µg/ml.

DOI: http://dx.doi.org/10.3329/dujs.v60i1.10328

Dhaka Univ. J. Sci. 60(1): 11-14, 2012 (January)

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Published

2012-04-14

How to Cite

Islam, M., Al-Amin, M., Siddiqi, M. M. A., Akter, S., Haque, M. M., Sultana, N., & Chowdhury, A. S. (2012). Isolation of Quercetin-3-O-beta-d-glucopyranoside from the Leaves of <i>Azadirachta Indica</i> and Antimicrobial and Cytotoxic screening of the Crude Extracts. Dhaka University Journal of Science, 60(1), 11–14. https://doi.org/10.3329/dujs.v60i1.10328

Issue

Vol. 60 No. 1 (2012)

Section

Articles