Synthesis of Ethyl 3,5-(Disubstituted Phenyl)-2-Isocyano-5-Oxopentanoate

Authors

  • Kawsari Akhter Department of Chemistry, University of Dhaka, Dhaka 1000, Bangladesh
  • Roksana Akter Department of Chemistry, University of Dhaka, Dhaka 1000, Bangladesh
  • S Mosaddeq Ahmed Department of Natural Science (Chemistry), American International University – Bangladesh (AIUB) 408/1 Kuratoli, Khilkhet, Dhaka-1229, Bangladesh
  • Md Ershad Halim Department of Chemistry, University of Dhaka, Dhaka 1000, Bangladesh

DOI:

https://doi.org/10.3329/dujs.v74i1.83479

Keywords:

Chalcones, ethyl cyanoacetate, sodium ethoxide, Michael addition

Abstract

The reactions between substituted chalcones 1a-d with ethyl cyanoacetate 2 were carried out in 1:1 molar ratio in the presence of sodium ethoxide as catalyst under refluxing condition to synthesize few chalcone derivatives, ethyl 3,5- (disubstituted phenyl)-2-isocyano-5-oxopentanoate, 3a-d. The structure of the compounds was determined by their chemical properties, UV, FT-IR, 1H-NMR, 13C-NMR, mass spectral data and elemental analyses.

Dhaka Univ. J. Sci. 74(1): 122-126, 2026 (January)

Downloads

Download data is not yet available.
Abstract
14
PDF
19

Author Biographies

Kawsari Akhter, Department of Chemistry, University of Dhaka, Dhaka 1000, Bangladesh

 

 

Roksana Akter, Department of Chemistry, University of Dhaka, Dhaka 1000, Bangladesh

 

 

S Mosaddeq Ahmed, Department of Natural Science (Chemistry), American International University – Bangladesh (AIUB) 408/1 Kuratoli, Khilkhet, Dhaka-1229, Bangladesh

 

 

Md Ershad Halim, Department of Chemistry, University of Dhaka, Dhaka 1000, Bangladesh

 

 

Downloads

Published

2026-01-28

How to Cite

Akhter, K., Akter, R., Ahmed, S. M., & Halim, M. E. (2026). Synthesis of Ethyl 3,5-(Disubstituted Phenyl)-2-Isocyano-5-Oxopentanoate. Dhaka University Journal of Science, 74(1), 122–126. https://doi.org/10.3329/dujs.v74i1.83479

Issue

Vol. 74 No. 1 (2026)

Section

Articles