Clinical Significance Of Serum HbeAg Among HbsAg Positive Patients
DOI:
https://doi.org/10.3329/fmcj.v5i2.6821Abstract
Hepatitis B Virus (HBV) infection is a menace worldwide as a major cause of morbidity & mortality through its consequences viz. acute hepatitis, chronic active, or persistent hepatitis, cirrhosis of liver and primary hepatocellular carcinoma. A total of 127 'HBsAg positive' patients were studied for 'HBeAg' by serum ELISA. Patient's aged between 11 to 60 years with a mean age 27.11. Out of 127 'HBsAg positive' cases 19 (14.96%) were 'HBeAg positive', of which maximum (21.43%) were among <20 years age group. Among 106 male patients 15 (14.155) & among 21 female patients 4 (19.055) were 'HBeAg positive'. Often the initiation of therapeutic approach remains a dilemma in absence of laboratory assessment of viraemic load or presence of HBV DNA through PCR or other DNA hybridization techniques. In such situations, alternatively, a significantly serum 'HBeAg' among 'HBsAg positive' patients may be taken as a surrogate marker for acute viral replication, and, thus apply justifying the initiation of antiviral chemotherapy without delay.DOI: 10.3329/fmcj.v5i2.6821
Faridpur Med. Coll. J. 2010;5(2):50-52
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Islam, M., Ahmed, R., Kabria, S., Hossain, M., Biswas, M., Bhuiyan, M., Ahmed, N., & Haq, N. (2011). Clinical Significance Of Serum HbeAg Among HbsAg Positive Patients. Faridpur Medical College Journal, 5(2), 50–52. https://doi.org/10.3329/fmcj.v5i2.6821
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