Comparison of Ocular Lens Thickness of Type-2 Diabetic Retinopathy Patients with Non-diabetic Control, Measured by High Resolution Ultrasonography

Authors

  • Khalada Parvin Deepa Specialist, Department of Radiology & Imaging, Ibrahim Cardiac Hospital & Research Institute. Dhaka, Bangladesh
  • Nusrat Ghafoor Associate Professor & Consultant, Department of Radiology & Imaging, Ibrahim Cardiac Hospital & Research Institute. Dhaka, Bangladesh
  • Nawshin Siraj Associate Professor & Senior Consultant & Head of Department of Radiology & Imaging. Ibrahim Cardiac Hospital & Research Institute. Dhaka, Bangladesh
  • Md Ziaul Haque Consultant Radiologist, United Lincolnshire Hospital NHS Trust, Radiology Department PilgrimHospital, Sibsey Road, Boston, Lincolnshire, UK.
  • Md Ubaidul Islam Specialist, Department of Radiology & Imaging, 250-bedded Hospital, Moulvibazar, Bangladesh
  • Most Razina Jubaida Specialist, Asgarali Hospital, Dhaka, Bangladesh

DOI:

https://doi.org/10.3329/icmj.v10i1-2.54002

Keywords:

Lens thickness, type-2 DM, diabetic retinopathy, non-diabetic healthy control, high resolution ultrasonography etc.

Abstract

Background & objective: The aim of this study was to verify whether the ocular lens of type-2 diabetic retinopathy patients was thicker (measured by high resolution Ultrasonography) than those of non-diabetic individuals.The study also evaluated the differences in lens thickness (LT) between right and left eyes of diabetic retinopathy patients, and the differences in LT between proliferative and background retinopathy cases.

Methods: This case-control study was conducted on 68 subjects (34 cases and 34 controls) aged 20-60 years in the Department of Radiology and Imaging, BIRDEM Hospital from March 2015 to February 2016. Adult patients suffering from type-2 diabetic retinopathy confirmed by slit-lamp examination were selected as cases, while apparently healthy subjects were taken as control. Patients with history of heart failure, ocular surgery, acute eye conditions, such as, conjunctivitis, scleritis, cataract or any other co-morbidities were excluded. Ocular mean lens thickness was measured by high resolution ultrasonography and was compared between case and control groups by Un-paired t-Test.

Results: The study showed that type 2 diabetic patients had significantly thicker lenses than their non-diabetic counterparts (in right eye:case 4.1 ± 0.3 mm versus control 3.7±0.1 mm, p<0.001 and in left eye:case 4.2 ± 0.3 mm vs. control 3.7±0.1 mm, p<0.001). The study also revealed that proliferative retinopathy cases had thicker lenses than any other diabetic retinopathy groups (p < 0.05) and there was also statistically significant difference of HbA1c level between proliferative and background type II diabetic retinopathy cases (p<0.05)

Conclusion: The study concluded that lens thickness is increased in type-2 diabetic retinopathy patients than that in non-diabetic healthy controls.The proliferative diabetic retinopathy cases possess thicker lens than the background retinopathy cases.

Ibrahim Card Med J 2020; 10 (1&2): 40-44

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Published

2021-03-15

How to Cite

Deepa, K. P., Ghafoor, N., Siraj, N., Haque, M. Z., Islam, M. U., & Jubaida, M. R. (2021). Comparison of Ocular Lens Thickness of Type-2 Diabetic Retinopathy Patients with Non-diabetic Control, Measured by High Resolution Ultrasonography. Ibrahim Cardiac Medical Journal, 10(1-2), 40–44. https://doi.org/10.3329/icmj.v10i1-2.54002

Issue

Vol. 10 No. 1-2 (2020)

Section

Original Article