Prevalence of polycystic ovary syndrome by the international evidence-based guidelines: A nationwide cross-sectional survey

Authors

  • Samirah Binte Illiyas Resident, Department of Endocrinology, Bangladesh Medical University, Shahbag, Dhaka, Bangladesh https://orcid.org/0009-0008-9353-1885
  • Md. Shahed Morshed PhD Researcher, Department of Endocrinology, Bangladesh Medical University, Dhaka, Bangladesh https://orcid.org/0000-0001-6115-2655
  • Mashfiqul Hasan PhD Researcher, Department of Endocrinology, Bangladesh Medical University, Dhaka, Bangladesh https://orcid.org/0000-0002-1805-5187
  • Tania Tofail PhD Researcher, Department of Endocrinology, Bangladesh Medical University, Dhaka, Bangladesh https://orcid.org/0000-0002-3925-6420
  • Hurjahan Banu Associate Professor, Department of Endocrinology, Bangladesh Medical University, Dhaka, Bangladesh https://orcid.org/0000-0002-8115-1761
  • Nusrat Sultana Associate Professor, Department of Endocrinology, Bangladesh Medical University, Dhaka https://orcid.org/0000-0002-6858-2110
  • Munira Afroz Siddika Resident, Department of Endocrinology, Bangladesh Medical University, Shahbag, Dhaka, Bangladesh
  • Md. Rafayel Islam FCPS trainee, Department of Endocrinology, Bangladesh Medical University, Dhaka, Bangladesh
  • Hafsa Mahrukh Endocrinologist, 250-Bedded General Hospital, Thakurgaon, Bangladesh https://orcid.org/0009-0007-6338-0265
  • Tahmina Ferdousi Endocrinologist, Department of Endocrinology, Govt. Employee Hospital, Fulbaria, Dhaka, Bangladesh https://orcid.org/0000-0003-0189-5232
  • Indira Roy Endocrinologist, National Institute of Burn and Plastic Surgery, Dhaka, Bangladesh https://orcid.org/0000-0003-1248-8843
  • Yasmin Aktar Associate Professor, Endocrinology Department, Bangladesh Medical College, Dhaka, Bangladesh https://orcid.org/0000-0002-3008-823X
  • Hilary Yasmin Resident, Department of Endocrinology, Bangladesh Medical University, Shahbag, Dhaka, Bangladesh
  • Farhana Rahman Resident, Department of Endocrinology, Bangladesh Medical University, Shahbag, Dhaka, Bangladesh
  • Nazia Akter Resident, Department of Endocrinology, Bangladesh Medical University, Shahbag, Dhaka, Bangladesh https://orcid.org/0009-0002-3509-1769
  • Abdullah Al Noman Bhuiyan Resident, Department of Endocrinology, Bangladesh Medical University, Shahbag, Dhaka, Bangladesh
  • Krishna Airi Resident, Department of Endocrinology, Bangladesh Medical University, Shahbag, Dhaka, Bangladesh
  • Rifat Hossain Ratul Research associate, PCOS study group, Department of Endocrinology, Bangladesh Medical University, Dhaka, Bangladesh https://orcid.org/0000-0003-0112-4489
  • Prodipta Chowdhury Resident, Department of Endocrinology, Bangladesh Medical University, Shahbag, Dhaka, Bangladesh https://orcid.org/0000-0001-9300-2950
  • Koushik Ashraf Resident, Department of Endocrinology, Bangladesh Medical University, Shahbag, Dhaka, Bangladesh https://orcid.org/0009-0003-8654-6484
  • Rayhan Ali Mollah Assistant Professor, Department of Orthopedics, Medical College For Women & Hospital, Uttara, Dhaka, Bangladesh
  • Muhammad Abul Hasanat Professor, Department of Endocrinology, Bangladesh Medical University, Dhaka, Bangladesh https://orcid.org/0000-0001-8151-9792

DOI:

https://doi.org/10.3329/jacedb.v4i20.84923

Keywords:

Antimullerian hormone, Hirsutism, Irregular menstrual cycle, Polycystic ovary syndrome, Prevalence

Abstract

Background: Data regarding the nationwide prevalence of polycystic ovary syndrome (PCOS) in Bangladeshi women is scarce. Additionally, a prevalence study using the stepwise decision-making approach, incorporating antimüllerian hormone (AMH), was also not reported.

Objectives: To determine the prevalence and characteristics of PCOS and its isolated diagnostic features among Bangladeshi women aged 10-45 years, using the 2023 International Evidence-based Guidelines, including AMH.

Methods: From April to September 2024, 1201 females were sampled across eight divisions of Bangladesh by history, physical examinations, and blood collection. Total testosterone (TT) and AMH levels were assessed, with specific cut-offs established from a healthy control group. Thyroid dysfunction and hyperprolactinemia were excluded.

Results: Of 1201 participants, 403 were excluded. Among 798 eligible women, 38 (4.8%) had both irregular cycles and significant hirsutism, 75 (9.4%) had only significant hirsutism, 141 (17.7%) had only irregular cycles, and 544 (68.2%) had neither. After TT and AMH evaluation and excluding two hyperprolactinemia cases, a 6.9% (55/798) prevalence was found among 57 women with probable PCOS. Familial predisposition, unhealthy sleep behaviour, and higher androgenic and metabolic features were observed in women with PCOS versus controls. Metabolic syndrome frequency was higher among adult PCOS (33.3% vs. 4.0%) than adolescent PCOS.

Conclusions: The prevalence of PCOS among Bangladeshi women was 6.9%, with distinctive features compared to controls. Women with isolated diagnostic criteria require further evaluation and long-term follow-up.

[J Assoc Clin Endocrinol Diabetol Bangladesh, 2025;4(Suppl 1): S37]

Abstract
2
PDF
0

Downloads

Published

2025-10-29

How to Cite

Illiyas, S. B., Morshed, M. S., Hasan, M., Tofail, T., Banu, H., Sultana, N., … Hasanat, M. A. (2025). Prevalence of polycystic ovary syndrome by the international evidence-based guidelines: A nationwide cross-sectional survey. Journal of Association of Clinical Endocrinologist and Diabetologist of Bangladesh, 4(20), S37. https://doi.org/10.3329/jacedb.v4i20.84923

Issue

Vol 4 : Supplementary issue for 9th ACEDBCON 2025

Section

Abstract of free paper - oral presentation

License

Copyright (c) 2025 Samirah Binte Illiyas, Md. Shahed Morshed, Mashfiqul Hasan, Tania Tofail, Hurjahan Banu, Nusrat Sultana, Munira Afroz Siddika, Md. Rafayel Islam, Hafsa Mahrukh, Tahmina Ferdousi, Indira Roy, Yasmin Aktar, Hilary Yasmin, Farhana Rahman, Nazia Akter, Abdullah Al Noman Bhuiyan, Krishna Airi, Rifat Hossain Ratul, Prodipta Chowdhury, Koushik Ashraf, Rayhan Ali Mollah, Muhammad Abul Hasanat

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.