Effect Of Surface Area Of Dialyzer Membrane On The Adequacy Of Haemodialysis

Authors

  • NS Chowdhury MBBS, M Phil, Assistant professor of Biochemistry, National Institute of Diseases of Chest and Hospital, Dhaka
  • FMM Islam MBBS, FCPS, Associate professor of Medicine, Sir Salimullah Medical College, Dhaka
  • F Zafreen MBBS, MPH, Associate Professor of Community Medicine, Medical College for Women & Hospital, Dhaka
  • BA Begum MBBS, MPhil, Professor of Biochemistry, Ad-Din Medical College, Dhaka
  • N Sultana MBBS, M Phil, Associate professor of Biochemistry, Dhaka Medical College
  • S Perveen MBBS, M Phil, Assitant professor of Biochemistry, Sir Salimullah Medical College
  • M Mahal MBBS, M Phil, Lecturer of Biochemistry, Shahid Suhrawardi Medical College, Dhaka

DOI:

https://doi.org/10.3329/jafmc.v7i2.10387

Keywords:

Haemodialysis, dialyzer membrane, duration

Abstract

Introduction: Patients with end stage renal disease require 12 hours of haemodialysis per week in three equal sessions (4 hours/day for 3 days/week). But the duration and frequency of treatment can be reduced by increasing the surface area of the dialyzer membrane.

Methods: In this prospective study 40 patients of end stage renal disease receiving haemodialysis for more than six months were included to observe the effects of increment in the surface area of the dialyzer membrane on the adequacy of haemodialysis.

Result: It was observed that 20 patients receiving haemodialysis on a dialyzer with membrane surface area of 1.2 m² did not have satisfactory solute clearance index. Urea reduction ratio was 45.9 ± 3.03 and fractional urea clearance (Kt/V) was 0.76 ± 0.09. On the other hand patients (20 cases) receiving haemodialysis on a dialyzer with membrane surface area of 1.3 m² had a urea reduction ratio 50.76± 5.16 and fractional urea clearance (Kt/V) 0.91 ± 0.16. All the patients of both groups received dialysis for 8 hours/week in two equal sessions (4 hours/day for 2 days/week). Statistically the increment was significant (p<0.001).

Conclusion: This study reveals, adequacy of dialysis can be increased by increasing the surface area of the dialyzer membrane. So, considering the poor socioeconomic condition of Bangladesh and patients' convenience, a short duration, low cost dialysis regime can be tried by increasing the surface area of dialyzer membrane.

DOI: http://dx.doi.org/10.3329/jafmc.v7i2.10387

JAFMC 2011; 7(2): 9-11

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Published

2012-04-16

How to Cite

Chowdhury, N., Islam, F., Zafreen, F., Begum, B., Sultana, N., Perveen, S., & Mahal, M. (2012). Effect Of Surface Area Of Dialyzer Membrane On The Adequacy Of Haemodialysis. Journal of Armed Forces Medical College, Bangladesh, 7(2), 9–11. https://doi.org/10.3329/jafmc.v7i2.10387

Issue

Vol. 7 No. 2 (2011)

Section

Original Papers

License

Submission of a manuscript for publication implies the transfer of the copyright from the author to the publisher upon acceptance. Accepted manuscripts become the permanent property of the Journal of Armed Forces Medical College and may not be reproduced by any means in whole or in part without the written consent of the publisher.