Cryptococcal Meningoencephalitis in an Immunosuppressed Patient with Chronic Lymphocytic Leukemia

Authors

  • Md Monirul Hoque Department of Microbiology, Armed Forces Institute of Pathology (AFIP), Dhaka, Bangladesh
  • Sonia Chakraborty Department of Microbiology, AFIP, Dhaka, Bangladesh
  • Arif Ahmed Khan Deputy Commandant, AFIP, Dhaka, Bangladesh

DOI:

https://doi.org/10.3329/jafmc.v16i2.55308

Keywords:

Cryptococcal meningoencephalitis, Chronic Lymphocytic Leukemia, Immunosuppressive drugs, Cerebrospinal fluid (CSF)

Abstract

Cryptococcal meningoencephalitis, an invasive fungal infection caused by an encapsulated fungus Cryptococcus neoformans should be suspected in immune compromised individuals with defective cell-mediated immunity and patients on immunosuppressive drugs with recent development of fever, confusion and loss of consciousness. A rapid diagnosis is fundamental for decreasing morbidity and mortality from cryptococcal disease. Cerebrospinal fluid (CSF) study and simple stain like India Ink Stain can be performed for diagnosis of cryptococcal meningoencephalitis. Here, we report a case of cryptococcal meningoencephalitis in chronic lymphocytic leukemia (CLL) patient on immunosuppressive drugs diagnosed by CSF study and India ink stain which responded dramatically with antifungal agents after diagnosis.

JAFMC Bangladesh. Vol 16, No 2 (December) 2020: 87-89

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Published

2021-11-08

How to Cite

Hoque, M. M. ., Chakraborty, S. ., & Khan, A. A. . (2021). Cryptococcal Meningoencephalitis in an Immunosuppressed Patient with Chronic Lymphocytic Leukemia. Journal of Armed Forces Medical College, Bangladesh, 16(2), 87–89. https://doi.org/10.3329/jafmc.v16i2.55308

Issue

Section

Case Reports