Immunogenicity of fowl typhoid vaccine in layer chickens

Abstract

The immunogenicity of available fowl typhoid vaccine was studied in layer chickens following usual and suggested schedule of vaccination. A total of 30 chickens were divided into three groups; group A (vaccinated following usual schedule of vaccination), B (vaccinated following suggested schedule of vaccination) and C (as control), each containing 10 layer chickens of Fayoumi breed. Chickens of group A and B were vaccinated with available fowl typhoid vaccine produced by the Governments laboratory at a dose rate of 0.5ml at each occasion through SC route, where 1^st dose was administered at 42 days and 35 days of age, respectively, and 2^nd dose at 72 days and 65 days of age, respectively. Blood samples were collected to obtain sera from each chicken at every 7 days interval up to 105 days post vaccination for determination of antibody titre following primary and secondary vaccination using microplate agglutination test. The highest mean antibody titre obtained from Group A was 460.8 than that of B was 435.2, respectively. Among the two groups, the highest mean antibody titre of 460.8 was obtained at 56 days post vaccination in group A following usual schedule of vaccination. It revealed that government supplied fowl typhoid vaccine induced higher level of antibody production in both usual and suggested schedule of vaccination.

Keywords: Immunogenicity; Fowl Typhoid; Vaccine; Layer chicken; Suggested; Usual

DOI: 10.3329/jbau.v7i1.4970

J. Bangladesh Agril. Univ. 7(1): 99-102, 2009