TY - JOUR AU - Rahman, Md Mahbubur AU - Ahmed, Kafiluddin PY - 2010/06/28 Y2 - 2024/03/29 TI - Efficacy of Intravenous Immunoglobulin in the Management of Guillain Barre Syndrome JF - Journal of Bangladesh College of Physicians and Surgeons JA - J. Bangladesh Coll. Phys. VL - 28 IS - 2 SE - Original Articles DO - 10.3329/jbcps.v28i2.5367 UR - https://banglajol.info/index.php/JBCPS/article/view/5367 SP - 81-85 AB - <p>A total number of 40 respondents consisting of 20 subjects<br />of Guillain barre syndrome in each group treated with<br />intravenous immunoglobulin (case) and without IVIg were<br />selected during the study period. Out of 20 cases, 12 (60%)<br />were male and 8 (40%) were females, ratio 1.5:1. Majority<br />of the cases were presented at second or third decade of<br />life. In control group, 11 (55%) were male and 9 (45%)<br />female, ratio 1.22:1. Majority of the patients had history of<br />upper respiratory tract infection or acute gastroenteritis 1<br />4 weeks preceding illness. All the patients had flaccid<br />paralysis in all four limbs with some sensory features without<br />bowel and bladder involvement. Thirteen patients from the<br />case and control groups developed respiratory failure requiring <br />ICU support. Cerebrospinal fluid study showed<br />albumin cytological dissociation. Nerve conduction study<br />showed features of demyelination, axonal loss or both.</p><p>There was significant improvement of GBS patients<br />treated with IVIg in respect of respiratory function,<br />muscle tone, muscle power, jerks and autonomic<br />function. ICU stay of patients treated with IVIg was<br />significantly shorter. Final outcome of patients treated<br />with IVIg showed one death. There was no death in<br />control group. The patient died probably due to severity<br />of disease and/or comorbid disease.<br /><strong><br />Key words:</strong> Intravenous Ig; Guillain barre syndrome<br /><br />DOI: 10.3329/jbcps.v28i2.5368<br /><br /><em>J Bangladesh Coll Phys Surg </em>2010; 28: 81-85</p> ER -