TY - JOUR AU - Ekundayo, FO AU - Oyeniran, KA AU - Adedokun, AD PY - 2016/10/21 Y2 - 2024/03/28 TI - Antimicrobial activities of some Streptomyces isolated from garden soil samples and fish pond water in Futa JF - Journal of Bio-Science JA - J bio-sci. VL - 22 IS - 0 SE - Articles DO - 10.3329/jbs.v22i0.30005 UR - https://banglajol.info/index.php/JBS/article/view/30005 SP - 21-29 AB - <p><strong>Context: </strong><em>Streptomyces </em>are potential sources for secondary metabolites possessing a variety of biological activities with antimicrobial activity, which is used for human and animal treatment. It is estimated these bacteria synthesize more than 7,000 metabolites. About 80% of these are made by members of the genus <em>Streptomyces</em>. <em>Streptomyces </em>spp. is known as producers of several bioactive metabolites which has antibiotic, antiparasitic, antitumor, insecticide, herbicide, etc.</p><p><strong>Objectives: </strong>Determine the antimicrobial activities of Streptomyces isolates and compare the efficacy of the antimicrobial activities of Streptomycetes with selected commercial antimicrobial agents.</p><p><strong>Materials and methods: </strong>Collection of samples and test organisms; physicochemical screening; antimicrobial assay (co-culture method); antibiotics sensitivity test (disc-diffusion assay).</p><p><strong>Result: </strong><em>Streptomyces griseoflavus, Streptomyces parvus </em>and <em>Streptomyces albidus </em>were isolated from dry soil while <em>Streptomyces vinaceus </em>and <em>Streptomyces globiosporus </em>from moist-fresh soil and fish pond water used for cultivation of cat fish <em>Clarias garienpinus </em>respectively. Out of these five (5) isolates isolated, 3 isolates (60%) exhibited antibacterial activity against the following pathogenic, nosocomial organisms: <em>Escherichia coli, Klebsiella pneumoniae, Salmonella typhi, Pseudomonas aeruginosa, Staphylococcus aureus, Candida </em>spp, <em>Aspergillus fumigatus</em>, <em>Aspergillus flavus</em>, <em>Aspergillus saprophyticus</em>, and <em>Trichoderma </em>spp respectively. <em>S. griseoflavus </em>demonstrated antibacterial activity against <em>K. pneumoniae</em>, <em>Trichoderma </em>spp and <em>Candida spp. S. albidus </em>against <em>S. typhi </em>and <em>A. fumigatus </em>while <em>S. parvus </em>was inhibitory to <em>S. aureus </em>and <em>A. fumigatus</em>. The active isolates inhibited bacteria growth (0 to 39.33 mm). Commercial antimicrobials used also demonstrated inhibitory effects against the test pathogens.</p><p><strong>Conclusion: </strong>The garden soil of FUTA farm contains <em>Streptomyces </em>spp. with antibacterial and antifungal activities.</p><p>J. bio-sci. 22: 21-29, 2014</p> ER -