Effect of preemptive intravenous ketorolac and bupivacaine infiltration on post operative pethidine consumption - a comparative study

Authors

  • Jalal Uddin Ahmed Associate Professor, Department of Anaesthesiology, Dhaka Dental College
  • Md Shahidul Islam Consultant, Department of Anaesthesiology, Dhaka Medical College & Hospital
  • Md Shafiqul Islam Assistant Professor, Shaheed Suhwardy Medical College & Hospital
  • Mantosh Kumar Mandal Assistant Professor, Department of Anaesthesiology, National Cancer Hospital and Research Institute, Mohakhali Dhaka
  • Mohammad Sirajul Islam Consultant Anaesthesiologist, Sarail Up-Zilla Health Complex, B Baria
  • Md Shamsuzzoha Assistant Professor, Dept. of Anaesthesia, Mansur Ali Medical College, Uttara, Dhaka
  • AKM Akhtaruzzaman Professor of Neuroanaesthesia, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka-

DOI:

https://doi.org/10.3329/jbsa.v23i1.18155

Keywords:

multimodal approach, postoperative pain, analgesia, ketorolac, infiltration, bupivacaine

Abstract

Background: Preemptive analgesia significantly reduces postoperative analgesic requirement. Multi modal approach for preemption has greater range of benefit and its use in treating postoperative pain has gaining popularity.

Objectives: To observe the effect of preemptive bupivacaine infiltration and intravenous ketorolac on postoperative pethidine consumption in single and multiple preemptive techniques.

Methods: One hundred and twenty patients of ASA physical status I&II requiring lower abdominal surgery under general anaesthesia were randomly allocated in four groups. Gr- A received bupivacaine infiltration and ketorolac injection, Gr-B received intravenous Ketorolac injection, Gr-C bupivacaine infiltration and Gr- D received nothing regarded as Control group. Data were analyzed by students t test, ANOVA and chi-square test as appropriate.

Results: Patients characteristics, duration of surgery, haemodynamic status were comparable in four groups. Pain intensity in VAS was significantly reduced in Gr-A (p<0.00) than other three groups. Total pethidine consumption was also reduced significantly in Gr-A (p<0.05).

Conclusion: Preemptive analgesics using in multiple modes gives better postoperative analgesia and patient comfort and less postoperative complications.

DOI: http://dx.doi.org/10.3329/jbsa.v23i1.18155

Journal of BSA, 2010; 23(1): 25-29

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Published

2014-03-01

How to Cite

Ahmed, J. U., Islam, M. S., Islam, M. S., Mandal, M. K., Islam, M. S., Shamsuzzoha, M., & Akhtaruzzaman, A. (2014). Effect of preemptive intravenous ketorolac and bupivacaine infiltration on post operative pethidine consumption - a comparative study. Journal of the Bangladesh Society of Anaesthesiologists, 23(1), 25–29. https://doi.org/10.3329/jbsa.v23i1.18155

Issue

Vol. 23 No. 1 (2010)

Section

Original Articles