Post operative nausea and vomiting after laparoscopic cholecystectomy: comparison of prophylactic effect of dexamethasone with ondansetron

Authors

  • M Younus Ali Department of Anesthesiology, Burn and Plastic Surgery Unit, DMCH
  • Raihan Uddin Department of Anesthesiology, BIRDEM
  • Amirul Islam Dept. of Anaesthesia,Analgesia and Intensive Care Medicine, BSMMU, Shahbag, Dhaka
  • Mustafa Kamal Dept. of Anaesthesia,Analgesia and Intensive Care Medicine, BSMMU, Shahbag, Dhaka
  • SM Rafiqul Islam Anaesthesiologist, Enam Medical College Hospital
  • AKM Shafiqur Rahman Department of Anesthesiology, BMCH.

DOI:

https://doi.org/10.3329/jbsa.v24i2.19803

Keywords:

Dexamethasone, ondansetron, laparoscopy, cholecystectomy, postoperative

Abstract

Background Postoperative nausea and vomiting after laparoscopic cholecystectomy under general anaesthesia are an unpleasant,distressing effects. Prophylactic use of dexamethesone reducing this effects.

Objective This study was designed to compare of dexamethasone and ondansetron for prevention of postoperative nausea and vomiting after laparoscopic cholecystectomy.

Methods Sixty patients who underwent laparoscopic cholesystectomy were randomly allocated into two groups. Group A(n=30) patients received 8mg dexamehtasone intravenously and Group B(n=30) patients received 8mg ondansetron intravenously one minute before induction of anaesthesia. All patients received standard general anaesthesia.Perioperative vital signs and postoperative nausea and vomiting were recorded.

Results The incidence of nausea was 13.4% in group A, 16.7% in group B(p>0.05) and vomiting was 6.6% in Group A, 13.4% in group B(p>0.05). The difference among the groups was not statistically significant.

Conclusion Intravenous dexamethasone was better to ondansetron in prevention of postoperative nausea and vomiting after laparoscopic cholecystectomy.

DOI: http://dx.doi.org/10.3329/jbsa.v24i2.19803

Journal of Bangladesh Society of Anaesthesiologists 2011; 24(2): 60-64

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Published

2014-08-02

How to Cite

Ali, M. Y., Uddin, R., Islam, A., Kamal, M., Islam, S. R., & Rahman, A. S. (2014). Post operative nausea and vomiting after laparoscopic cholecystectomy: comparison of prophylactic effect of dexamethasone with ondansetron. Journal of the Bangladesh Society of Anaesthesiologists, 24(2), 60–64. https://doi.org/10.3329/jbsa.v24i2.19803

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Original Articles