Effect of Hydroxyethyl starch for preloading in pre-eclamptic patients undergoing caesarean section under sub-arachnoid block : A comparison with Hartmans solutions
DOI:
https://doi.org/10.3329/jbsa.v17i1.4044Keywords:
HES, Pre-eclampsia, Subarachnoid blockAbstract
When sub-arachnoid block is performed on preeclamptic mother, profound hypotension may occur. To maintain haemodynamic stability, patients can be preloaded with crystalloid or colloid solution. 60 pre-eclamptic pregnant mothers with ASA grade I & II were randomly divided into two equal groups by blind envelop method. In Group- A, patients were preloaded with Hartman's solutions @ 15ml/kg and in Group-B, with 6% Hetastarch @ 5ml/kg. The results of the study showed that hypotension was less in group-B (10%) than group-A (56.66%). Total additional volume of fluid required to treat hypotension was less in Group-B, (803.33ml) than Group-A (1526.66ml). Only three (3) cases of Group-B required ephedrine 0.83±2.65 mg) in comparison to 17 cases of Group- A (4.50±4.79 mg). So, it can be concluded that preloading of pre-eclamptic pregnant mothers with 6% Hetastarch is superior to Hartman's solution in caesarean section after sub-arachnoid block to maintain a stable haemodynamic status.
Key words: HES; Pre-eclampsia; Subarachnoid block
Journal of BSA, Vol. 17, No. 1 & 2, 2004 p.7-11
DOI: http://dx.doi.org/10.3329/jbsa.v17i1.4044
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