https://banglajol.info/index.php/JBSP/issue/feed Journal of Bangladesh Society of Physiologist 2019-07-07T06:40:20+00:00 Dr Sultana Ferdousi sferdousiratna@gmail.com Open Journal Systems <p>Established in 2006 by the Bangladesh Society of Physiologist Full text articles available.</p><p>Journal of Bangladesh Society of Physiologist is included on <a title="DOAJ" href="https://doaj.org/toc/2219-7508" target="_blank">DOAJ</a>.</p> https://banglajol.info/index.php/JBSP/article/view/41994 Effect of Emblica Officinalis (amloki) on iron status in pregnant women with iron deficiency anaemia 2019-07-07T06:40:10+00:00 Tahmina Akter tahmina.runa.akter1@gmail.com Qazi Shamima Akhter tahmina.runa.akter1@gmail.com <p><strong>Background: </strong>Common clinical practice of prescribing Iron supplementation for Iron deficiency anemia (IDA) in pregnancy is associated with a number of side effects. <em>Emblica officinalis </em>(amloki) is a well known dietary supplement used by traditional practitioners to treat anemia.</p> <p><strong>Objective</strong>: To evaluate the effects of oral supplementation of <em>Emblica officinalis </em>on iron status in pregnant women with IDA.</p> <p><strong>Methods: </strong>This prospective interventional study was carried out in the Department of Physiology, Dhaka Medical College (DMC), Dhaka from July 2016 to June 2017 on 43 pregnant women aged 18 to 36 years between 13<sup>th</sup> to 20<sup>th</sup> weeks of gestation with IDA. They were recruited from the Out-patient department of Obstetrics and Gynaecology, DMC Hospital. Among them 24 were supplemented with amloki and iron (IAS) and 19 women received only iron supplementation (IS). Study variables were estimated at the baseline and after 45 days of supplementation. Serum iron, ferritin and Total iron binding capacity (TIBC) were estimated following standard laboratory methods. Data were expressed as mean ± SD. Paired and Unpaired Student’s t-test were used for statistical analysis.</p> <p><strong>Results: </strong>Serum iron levels were significantly higher (p&lt;0.001) and serum TIBC were significantly lower (p&lt;0.001) in both groups after supplementation compared to their baseline value. But post supplementation serum ferritin level was significantly higher (p&lt;0.01) only in IAS group compared to that of the baseline. Again, after intervention, serum iron level was significantly higher (p&lt;0.05) and serum TIBC was significantly lower (p&lt;0.01) in IAS group when compared with those of IS group.</p> <p><strong>Conclusions: </strong>Data concluded that oral <em>Emblica officinalis </em>supplement along with iron was more effective than only iron supplementation to improve serum iron status in pregnant women with IDA.</p> <p>J Bangladesh Soc Physiol. 2019, June; 14(1): 1-6</p> 2019-06-27T00:00:00+00:00 ##submission.copyrightStatement## https://banglajol.info/index.php/JBSP/article/view/41995 Music therapy on non linear assessment of cardiac autonomic function in patients with major depressive disorder 2019-07-07T06:40:12+00:00 Shams Ruhani Islam shams.ruhani@yahoo.com Sultana Ferdousi shams.ruhani@yahoo.com <p><strong>Background :</strong>Non linear measure of heart rate variability (HRV) is an emerging method to detect changes in cardiac autonomic nerve function in major depressive disorder (MDD).</p> <p><strong>Objective: </strong>To observe the effect of music therapy on non linear measures of HRV in newly diagnosed MDD patients.</p> <p><strong>Methods: </strong>This prospective interventional study was done in the Department of Physiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Shahbag, Dhaka in 2018 on 60 newly diagnosed MDD patients aged 20-40 years, both male and female. They were further subdivided into 30 patients with only antidepressant medication (Mirtazapine) and 30 patients received music therapy with Raga kafi (Rabindrasangeet) along with the same medication for 3 months. Age, sex and BMI matched healthy control were also enrolled. HRV non linear parameters were recorded by Power Lab 8/35. For statistical analysis paired sample ‘t’ test and independent sample ‘t’ test were done.</p> <p><strong>Result: </strong>SD1, SD2 and SD1/SD2 were found significantly lower in MDD patients compared to healthy control at baseline. After 3 months of music therapy, significant increment of these parameters occurred with trend of improvement in cardiac autonomic nerve function (CANF) in these patients.</p> <p><strong>Conclusion: </strong>This study concluded that music therapy can improve CANF by increasing parasympathetic and reducing sympathetic activity in MDD patients.</p> <p>J Bangladesh Soc Physiol. 2019, June; 14(1): 7-13</p> 2019-06-27T00:00:00+00:00 ##submission.copyrightStatement## https://banglajol.info/index.php/JBSP/article/view/41996 Vitamin D3 – does it correlate with exercise tolerance in stable COPD? 2019-07-07T06:40:13+00:00 Samia Hassan dr.samiapeu@gmail.com Taskina Ali dr.samiapeu@gmail.com Kazi Saifuddin Bennoor dr.samiapeu@gmail.com Md Ali Hossain dr.samiapeu@gmail.com Mustafizur Rahman dr.samiapeu@gmail.com Mohammad Abdus Shakur Khan dr.samiapeu@gmail.com Sharkia Khanam Rosy dr.samiapeu@gmail.com Salsa Bil Nahar dr.samiapeu@gmail.com Maksuda Binte Mahmood dr.samiapeu@gmail.com <p><strong>Background</strong>: Though the classic function of vitamin D<sub>3</sub> in skeletal health is established, but its new role has been discovered in tissues and organs other than bones. Vitamin D<sub>3</sub> deficiency has been found in patients with various morbid conditions, such as cardiovascular diseases, autoimmune diseases, infectious diseases, Diabetes mellitus and malignancies including respiratory ailments.</p> <p><strong>Objectives</strong>: This cross sectional study was designed to evaluate the status of this fat soluble vitamin D<sub>3</sub> and its correlation with exercise tolerance in stable COPD patients.</p> <p><strong>Methods: </strong>For this purpose, 47 male, smoker (&gt;4 pack years), stable (who has not experienced any acute exacerbation, hospitalizations, urgent care visits, or changes in routine medications within 4 weeks prior to study), COPD patients (post bronchodilator FEV<sub>1</sub>/FVC&lt;0.70; duration &gt;4 years) of &gt;40 years of age, were selected from the Out Patient Department of National Institute of Diseases of Chest and Hospital (NIDCH), Dhaka. For the assessment of vitamin D<sub>3</sub> status, their serum 25-hydroxycholecalciferol [25(OH)D], for exercise tolerance, 6 min walk distance [6MWD; by 6 min walk test], peripheral capillary oxygen saturation (SpO2) [by pulse oximetry], level of dyspnea and fatigue [by Modified BORG scale], were measured. The data were expressed as percentage and mean ±SEM and were statistically analyzed by Pearson’s correlation coefficient test, where p&lt;0.05 was accepted as significant.</p> <p><strong>Results: </strong>Out of 47 stable COPD patients, 46 (97.8%) were with serum 25(OH) D &lt; 30 ng/ml. In addition, 6MWD was positively (p£0.05) and dyspnea (p£0.001) along with fatigue (p£0.05) score were negatively correlated with serum 25(OH)D level in these stable COPD patients.</p> <p><strong>Conclusion: </strong>This study result concluded that, majority patients with stable COPD had D3 deficiency and this D<sub>3</sub> deficiency showed significant correlation with decrement of exercise tolerance.</p> <p>J Bangladesh Soc Physiol. 2019, June; 14(1): 14-20</p> 2019-06-27T00:00:00+00:00 ##submission.copyrightStatement## https://banglajol.info/index.php/JBSP/article/view/41997 Serum zinc and copper levels in alopecia 2019-07-07T06:40:15+00:00 Farhana Rahman runanewlook@gmail.com Qazi Shamima Akhter runanewlook@gmail.com <p><strong>Background: </strong>Emerging evidence suggests that trace elements such as zinc (Zn<sup>2+</sup>) and copper (Cu<sup>2+</sup>) are essential cofactor for multiple enzymes and have functional activities within hair follicles. So its deficiencies may cause hair loss.</p> <p><strong>Objective: </strong>To assess the serum zinc and copper levels in alopecia.</p> <p><strong>Methods: </strong>This cross sectional study was conducted in the Department of Physiology, Dhaka Medical College, Dhaka from January to December during 2017. Thirty five patients icluding both sexes with hair loss aged 18 to 45 years were study group and 35 ages and BMI matched healthy subjects were control group. Serum zinc and copper levels were estimated by flame atomic absorption spectrophotometry. For statistical analysis Unpaired Student’s‘t’ test and Chi square tests were performed.</p> <p><strong>Results: </strong>Serum Zn<sup>2+</sup> and Cu<sup>2+</sup> levels were significantly (<em>p</em>&lt;0.001) lower in study group than those of control group.</p> <p><strong>Conclusions: </strong>It was concluded that serum Zn<sup>2+</sup> and Cu<sup>2+</sup> deficiencies are associated with hair loss patients.</p> <p>J Bangladesh Soc Physiol. 2019, June; 14(1): 21-25</p> 2019-06-27T00:00:00+00:00 ##submission.copyrightStatement## https://banglajol.info/index.php/JBSP/article/view/41998 Effect of slow breathing exercise on non linear Heart rate variability in transfusion dependent thalassemic patients 2019-07-07T06:40:16+00:00 Kamol Chandra Das kamolchandradas@yahoo.com Sultana Ferdousi kamolchandradas@yahoo.com <p><strong>Background: </strong>Nonlinear measure of heart rate variability (HRV) is an emerging tool to detect changes in cardiac autonomic nerve function (CANF) in transfusion dependent thalassemic (TDT) patients. Slow breathing exercise (SBE) can significantly improve HRV in health and various diseases.</p> <p><strong>Objective: </strong>To observe the effect of slow breathing exercise (SBE) on non linear measures of HRV in TDT patients.</p> <p><strong>Methods: </strong>This prospective interventional study was done in the Department of Physiology, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka in 2018 on 60 male TDT patients aged 15-30 years. Thirty patients received conventional treatment and 30 patients performed slow breathing exercise along with the conventional treatment for 3 months. Age and sex matched 30 healthy control were enrolled. All subjects were followed up at baseline and after 3 months. Non linear (Poincare) HRV parameters were recorded by Power Lab 8/35 AD Instrument, Australia. For statistical analysis paired sample ‘ t’ test and independent sample ‘t’ test were used.</p> <p><strong>Result: </strong>SD1, SD2 and SD1/SD2 were found significantly lower in TDT patients compared to healthy control at baseline. After 3 months of slow breathing exercise, significant increment of these parameters occurred with trend of improvement in cardiac autonomic nerve function in this group of patients.</p> <p><strong>Conclusion: </strong>Slow breathing exercise may improve cardiac autonomic nerve function and sympathovagal balance in transfusion dependent thalassemic patients.</p> <p>J Bangladesh Soc Physiol. 2019, June; 14(1): 26-32</p> 2019-06-27T00:00:00+00:00 ##submission.copyrightStatement## https://banglajol.info/index.php/JBSP/article/view/41999 Effect of omega-3 fatty acid supplementation on serum fasting glucose and HbA1c levels in type-2 Diabetes Mellitus 2019-07-07T06:40:18+00:00 Tamanna Binte Habib hshimul09@gmail.com Qazi Shamima Akhter hshimul09@gmail.com <p><strong>Background: </strong>Diabetes Mellitus (DM) is a major non-communicable health problem that have effects on glycemic status. Oral omega-3 fatty acid supplementation may improve glycemic status in diabetic patient.</p> <p><strong>Objective: </strong>To observe the effect of supplementation of omega-3 fatty acid on fasting serum glucose (FSG) and glycosylated hemoglobin (HbA1c) levels in type 2 DM.</p> <p><strong>Methods: </strong>This prospective interventional study was conducted from January 2017 to December 2017. A total numbers of 52 diagnosed type 2 diabetic patients(type-2 DM) of both sexes were selected with age 40 to 50 years. Among them, 27 type 2 diabetic patient with supplementation of omega 3 fatty acid (2g/day) for 12 weeks was considered as study group. Another 25 type 2 diabetic patients without supplementation of omega 3 fatty acid was considered as control group. The study subjects were selected from Outpatient Department of Endocrinology, Dhaka Medical College Hospital, Dhaka and personal contact from Dhaka city. FSG was estimated by enzymatic colorimetric method and HbA1c was estimated by turbidimetric inhibition immunoassay method. The study parameters were measured at base line and after 12 weeks of study period in both groups. For statistical analysis, Student’s paired ‘t’ test and Student’s unpaired ‘t’ test were performed as applicable using SPSS for windows version 16.0<strong>.</strong></p> <p><strong>Results</strong>: In this study serum FSG and HbA1c levels were significantly lower (p&lt;.001) in diabetic patients after supplementation with omega-3 fatty acid in comparison to that of their baseline value. Again, after 12 weeks, FSG and HbA1c levels significantly decreased (p&lt;.001) in omega-3 fatty acid supplemented diabetic patients compared to control group. In control group, there was no significant change in FSG and HbA1c levels between baseline and after 3 months of follow-up.</p> <p><strong>Conclusion: </strong>From the results of the study, it can be concluded that omega-3 fatty acid may improve serum FSG and HbA1c levels in type 2 diabetic patient and may be helpful to minimize the complications of type-2 DM.</p> <p>J Bangladesh Soc Physiol. 2019, June; 14(1): 33-37</p> 2019-06-27T00:00:00+00:00 ##submission.copyrightStatement## https://banglajol.info/index.php/JBSP/article/view/42000 Serum zinc, copper and ferritin levels in transfusion dependent thalassemia patients with iron chelator therapy 2019-07-07T06:40:19+00:00 Fatema Tuz Munira munira277@yahoo.com Shelina Begum munira277@yahoo.com <p><strong>Background: </strong>Transfusion dependent thalassemia (TDT) patients require regular blood transfusion and iron chelator therapy to maintain their life. Iron chelator may alter serum zinc and copper level in TDT patients.</p> <p><strong>Objective: </strong>To observe serum zinc and copper and ferritin levels in transfusion dependent thalassemic patients treated with iron chelator.</p> <p><strong>Method: </strong>The present cross sectional study was carried out in the department of Physiology, BSMMU, Dhaka between September 2017 to February 2019. Thirty cases of TDT, aged 5-40 year were included in the study group. Age and sex matched 30 healthy subjects were also studied as control. All the TDT patients were selected from the outpatient Department of Hematology and Transfusion Medicine, BSMMU, Dhaka. Serum zinc was measured by Spectrophotometric method and serum copper and ferritin levels were measured by colorimetric method. For statistical analysis independent sample t test was used.</p> <p><strong>Result: </strong>The mean serum zinc level was significantly (p&lt;0.05) lower and serum ferritin level was significantly (p&lt;0.001) higher in TDT compared to control. Again, mean serum copper level and Zn/Cu ratio were not significantly (p&gt;0.05) different in study groups compared to that of control. In addition, 3.3 % TDT patients had hypozincemia and 13.3% TDT patients had hypercupremia.</p> <p><strong>Conclusion: </strong>This study may conclude that low serum zinc level and high copper level may be associated with TDT patients treated by combined deferoxamine (DFO) &amp; deferiprone (DFP) iron chelator.</p> <p>J Bangladesh Soc Physiol. 2019, June; 14(1): 38-42</p> 2019-06-27T00:00:00+00:00 ##submission.copyrightStatement##