The Current Researches on T Follicular Helper Cells and Associated Diseases
DOI:
https://doi.org/10.3329/jemc.v2i2.12843Keywords:
T follicular helper, Differentiation, B cell, Associated diseasesAbstract
T follicular helper (Tfh) cell is a new subpopulation of CD4+ T cell family, whose differentiation is affected by Bcl-6, Blimp-1, STAT3, STAT5 and so on, and it could affect or decide the development of other subsets of CD4+ T cells. The important function of Tfh cell is to help B cell mediate humoral immunity, many researches have proved that Tfh cells participate in the development of autoimmune disease, immunodeficient disease, tumor and infectious diseases.
DOI: http://dx.doi.org/10.3329/jemc.v2i2.12843
J Enam Med Col 2012; 2(2): 85-91
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