The Current Researches on T Follicular Helper Cells and Associated Diseases

Authors

  • Jianwei Zhou Clinic Laboratory, Affiliated Hospital of Jining Medical College, Jining 272029, Shandong province
  • Cui Kong Cardiovascular Medicine Department, Affiliated Hospital of Jining Medical College, Jining 272029, Shandong Province

DOI:

https://doi.org/10.3329/jemc.v2i2.12843

Keywords:

T follicular helper, Differentiation, B cell, Associated diseases

Abstract

T follicular helper (Tfh) cell is a new subpopulation of CD4+ T cell family, whose differentiation is affected by Bcl-6, Blimp-1, STAT3, STAT5 and so on, and it could affect or decide the development of other subsets of CD4+ T cells. The important function of Tfh cell is  to help B cell mediate humoral immunity, many researches have proved that Tfh cells participate in the development of autoimmune disease, immunodeficient disease, tumor and    infectious diseases.

DOI: http://dx.doi.org/10.3329/jemc.v2i2.12843

J Enam Med Col 2012; 2(2): 85-91

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Published

2012-12-05

How to Cite

Zhou, J., & Kong, C. (2012). The Current Researches on T Follicular Helper Cells and Associated Diseases. Journal of Enam Medical College, 2(2), 85–91. https://doi.org/10.3329/jemc.v2i2.12843

Issue

Section

Review Article