Association of Human Papilloma Virus Infection and Oral Squamous Cell Carcinoma in Bangladesh

Authors

  • Mahmuda Akhter Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Bangabandhu Sheikh Mujib Medical University, Dhaka,
  • Liaquat Ali Bangladesh Institute of Health Science, Darus Salam, Mirpur, Dhaka,
  • Zahid Hassan Department of Physiology and Molecular Biology, BIRDEM, 122 Kazi Nazrul Islam Avenue, Dhaka,
  • Imran Khan Department of Physiology and Molecular Biology, BIRDEM, 122 Kazi Nazrul Islam Avenue, Dhaka,

DOI:

https://doi.org/10.3329/jhpn.v31i1.14750

Keywords:

Human papilloma virus (HPV), HPV type 16, HPV type 18, Oral cancer, Polymerase chain reaction, Bangladesh

Abstract

Oral squamous cell carcinoma is the sixth most common malignancy worldwide. In Bangladesh, it comprises 20% of the whole body malignancies. Several studies found that 15% to 25% of oropharyngeal cancer cases are associated with human papilloma virus (HPV). This study is done to find the association of human papilloma virus subtypes, particularly HPV type 16 and HPV type 18, with the oral squamous cell carcinoma in Bangladeshi patients. In total, 34 diagnosed patients of oral squamous cell carcinoma were included in the study. Extracted DNA from the cancerous tissues was checked for PCR reaction to detect the subtypes of human papilloma virus. Data of the present study suggest that oral squamous cell carcinoma are almost absent in Bangladeshi patients with human papilloma virus, particularly HPV 16 and 18.

J HEALTH POPUL NUTR 2013 Mar;31(1):65-69

DOI: http://dx.doi.org/10.3329/jhpn.v31i1.14750

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Published

2013-04-25

How to Cite

Akhter, M., Ali, L., Hassan, Z., & Khan, I. (2013). Association of Human Papilloma Virus Infection and Oral Squamous Cell Carcinoma in Bangladesh. Journal of Health, Population and Nutrition, 31(1), 65–69. https://doi.org/10.3329/jhpn.v31i1.14750

Issue

Vol. 31 No. 1 (2013)

Section

Original Papers