Association of Serum Albumin with Short-Term Outcome of Ischemic Stroke

Authors

  • Md Bakhtiar Azam Assistant Professor, Department of Neurology, National Institute of Neurosciences & Hospital, Dhaka, Bangladesh
  • AFM Al Masum Khan Medical Officer, Department of Neurophysiology, National Institute of Neurosciences & Hospital, Dhaka, Bangladesh
  • Muhammad Enayet Hussain Associate Professor, Department of Neurophysiology, National Institute of Neurosciences & Hospital, Dhaka, Bangladesh
  • Riaz Ferdaus Associate Professor, Health Administration, Franciscan Missionaries of Our Lady University, LA, USA
  • Sirajee Shafiqul Islam Associate Professor, Department of Interventional Neurology, National Institute of Neurosciences & Hospital, Dhaka, Bangladesh
  • ATM Hasibul Hasan Registrar, Department of Interventional Neurology, National Institute of Neurosciences & Hospital, Dhaka, Bangladesh
  • Md Amir Hossain Assistant Professor, Department of Neurology, National Institute of Neurosciences & Hospital, Dhaka, Bangladesh
  • Dewan Md Elyas Assistant Professor, Department of Neurology, National Institute of Neurosciences & Hospital, Dhaka, Bangladesh
  • Muhammad Abdul Momen Khan Assistant Professor, Department of Neurology, National Institute of Neurosciences & Hospital, Dhaka, Bangladesh
  • Khairul Kabir Patwari Associate Professor, Department of Neurology, National Institute of Neurosciences & Hospital, Dhaka, Bangladesh
  • Mohammad Ahtashamul Haque Assistant Professor, Department of Oral & Maxillo-Facial Surgery, Dhaka Dental College, Dhaka, Bangladesh
  • Quazi Deen Mohammad Professor & Director, National Institute of Neurosciences & Hospital, Dhaka, Bangladesh

DOI:

https://doi.org/10.3329/jninb.v5i2.43012

Keywords:

Ischemic stroke; albumin; short-term outcome; neuroprotection

Abstract

Background: Serum albumin is proved to be a neuroprotective substance in experimental studies in focal cerebral ischemia.

Objective: The aim of this study was to find out any association of serum albumin with the short term outcome of ischemic stroke.

Methodology: This observational study was conducted in the Department of Neurology and Department of Internal Medicine at Dhaka Medical College Hospital, Dhaka from January 2011 to December 2011. A total of fifty consecutive patient with first ever ischemic stroke were included. Short term outcome was measured on day 7 using the modified Rankin Scale (mRS) and poor outcome was defined as mRS score 4 to 6 or death. Serum albumin was measured within 24 hours of onset of stroke.

Result: Serum albumin was found to be significantly associated with the short-term outcome of ischemic stroke [P-value of Chi square (df = 1) was 0.010]. On logistic regression analysis, SA level [p = 0.018, Odds Ratio (OR) =5.817; 95% confidence interval: 1.348 to 25.106] remained significantly and positively associated with the short-term outcome of ischemic stroke.

Conclusion: Serum albumin is significantly associated with the short-term outcome of ischemic stroke and lower level predicts poor outcome and higher level predicts good outcome.

Journal of National Institute of Neurosciences Bangladesh, 2019;5(2): 101-105

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Published

2019-09-07

How to Cite

Azam, M. B., Khan, A. A. M., Hussain, M. E., Ferdaus, R., Islam, S. S., Hasan, A. H., Hossain, M. A., Md Elyas, D., Khan, M. A. M., Patwari, K. K., Haque, M. A., & Mohammad, Q. D. (2019). Association of Serum Albumin with Short-Term Outcome of Ischemic Stroke. Journal of National Institute of Neurosciences Bangladesh, 5(2), 101–105. https://doi.org/10.3329/jninb.v5i2.43012

Issue

Vol. 5 No. 2 (2019)

Section

Original Research Articles

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