Association of Serum Albumin with Short-Term Outcome of Ischemic Stroke

Authors

  • Md Bakhtiar Azam Assistant Professor, Department of Neurology, National Institute of Neurosciences & Hospital, Dhaka, Bangladesh
  • AFM Al Masum Khan Medical Officer, Department of Neurophysiology, National Institute of Neurosciences & Hospital, Dhaka, Bangladesh
  • Muhammad Enayet Hussain Associate Professor, Department of Neurophysiology, National Institute of Neurosciences & Hospital, Dhaka, Bangladesh
  • Riaz Ferdaus Associate Professor, Health Administration, Franciscan Missionaries of Our Lady University, LA, USA
  • Sirajee Shafiqul Islam Associate Professor, Department of Interventional Neurology, National Institute of Neurosciences & Hospital, Dhaka, Bangladesh
  • ATM Hasibul Hasan Registrar, Department of Interventional Neurology, National Institute of Neurosciences & Hospital, Dhaka, Bangladesh
  • Md Amir Hossain Assistant Professor, Department of Neurology, National Institute of Neurosciences & Hospital, Dhaka, Bangladesh
  • Dewan Md Elyas Assistant Professor, Department of Neurology, National Institute of Neurosciences & Hospital, Dhaka, Bangladesh
  • Muhammad Abdul Momen Khan Assistant Professor, Department of Neurology, National Institute of Neurosciences & Hospital, Dhaka, Bangladesh
  • Khairul Kabir Patwari Associate Professor, Department of Neurology, National Institute of Neurosciences & Hospital, Dhaka, Bangladesh
  • Mohammad Ahtashamul Haque Assistant Professor, Department of Oral & Maxillo-Facial Surgery, Dhaka Dental College, Dhaka, Bangladesh
  • Quazi Deen Mohammad Professor & Director, National Institute of Neurosciences & Hospital, Dhaka, Bangladesh

DOI:

https://doi.org/10.3329/jninb.v5i2.43012

Keywords:

Ischemic stroke; albumin; short-term outcome; neuroprotection

Abstract

Background: Serum albumin is proved to be a neuroprotective substance in experimental studies in focal cerebral ischemia.

Objective: The aim of this study was to find out any association of serum albumin with the short term outcome of ischemic stroke.

Methodology: This observational study was conducted in the Department of Neurology and Department of Internal Medicine at Dhaka Medical College Hospital, Dhaka from January 2011 to December 2011. A total of fifty consecutive patient with first ever ischemic stroke were included. Short term outcome was measured on day 7 using the modified Rankin Scale (mRS) and poor outcome was defined as mRS score 4 to 6 or death. Serum albumin was measured within 24 hours of onset of stroke.

Result: Serum albumin was found to be significantly associated with the short-term outcome of ischemic stroke [P-value of Chi square (df = 1) was 0.010]. On logistic regression analysis, SA level [p = 0.018, Odds Ratio (OR) =5.817; 95% confidence interval: 1.348 to 25.106] remained significantly and positively associated with the short-term outcome of ischemic stroke.

Conclusion: Serum albumin is significantly associated with the short-term outcome of ischemic stroke and lower level predicts poor outcome and higher level predicts good outcome.

Journal of National Institute of Neurosciences Bangladesh, 2019;5(2): 101-105

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Published

2019-09-07

How to Cite

Azam, M. B., Khan, A. A. M., Hussain, M. E., Ferdaus, R., Islam, S. S., Hasan, A. H., … Mohammad, Q. D. (2019). Association of Serum Albumin with Short-Term Outcome of Ischemic Stroke. Journal of National Institute of Neurosciences Bangladesh, 5(2), 101–105. https://doi.org/10.3329/jninb.v5i2.43012

Issue

Vol. 5 No. 2 (2019)

Section

Original Research Articles

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