Frequency and Topography of AstrocyticTumor: Experience of 567 Cases at Referral Neuroscience Hospital in Bangladesh

Authors

  • Md Nowfel Islam Professor and Head, Department of Neuropathology, National Institute of Neurosciences & Hospital, Dhaka, Bangladesh
  • Naila Haq Associate Professor, Department of Neuropathology, National Institute of Neurosciences & Hospital, Dhaka, Bangladesh
  • Md Badius Salam Assistant. Professor and Head, Department of Radiation Oncology, Sir Salimullah Medical College, Dhaka, Bangladesh
  • Monsur Ahmed Assistant Professor. Department of Neurosurgery, National Institute of Neurosciences &Hospital, Dhaka, Bangladesh
  • Sk Muhammad Ekramullah Professor and head, Department of Pediatric Neurosurgery, National Institute of Neurosciences & Hospital, Dhaka, Bangladesh
  • Md Zahed Hossain Professor of Neurosurgery, National Institute of Neurosciences& Hospital, Dhaka, Bangladesh
  • Sk Sader Hossain Professor and Head, Department of Neurosurgery, National Institute of Neurosciences & Hospital, Dhaka, Bangladesh
  • Sadia Shirin Medical Officer, Department of Neuropathology, National Institute of Neurosciences & Hospital, Dhaka, Bangladesh

DOI:

https://doi.org/10.3329/jninb.v6i2.50748

Keywords:

Topography;glial tumors; subtypes; gender

Abstract

Background: Glioma is the most commonly occurring malignant brain tumor that varies by age, sex, race or ethnicity. A very few number of records on CNS tumors are available in Bangladesh. National Institute of Neurosciences and Hospital (NINS), Dhaka has a good number of CNS surgeries. Regularly both tumorous and non-tumorous ICSOL samples are examined here.

Objective: The aim of the study was to see the subtypes, frequency and topography of Astrocytic tumors at NINS setting.

Methodology: Data from the department of Neuropathology department of NINS since January 2013 to June 2019 were evaluated. Tissue were fixed in formalin, paraffin embedded, stained with H&E. Histomorphology and WHO 2007 CNS tumor classification were used.

Result: From 3945 routine sample 567 cases were sorted out as Astrocytic tumor. Total male were 61% (346) and female 39% (221), male to female ratio was 1.6:1. The mean age was 32.64 and ranged from 1 to 80 years. Sixty six percent (66%) tumors were in supratentorial compartment, 15% infratentorial, 6.3% spinal and 9.7% in midline areas like thalamus, hypothalamus and seller region. In this study 34.6% (196) cases were Glioblastoma, followed by Anaplastic Astrocytoma 8.3%(47), Diffuse Astrocytoma 29% (165), Pilocytic Astrocytoma 26.6% (151), Pilomyxoid Astrocytoma 0.4% (2), Subependymal giant cell Astrocytoma 0.9% (5) and Pleomorphic Xanthoastrocytoma 0.1 (0.1). Topographically 66% glial tumors are supratentorial. Among the glial tumors 34.6% is Glioblastoma, 8.3% Anaplastic Astrocytoma, 29% Diffuse Astrocytoma and 26.6% Pilocytic astrocytoma. Common age group of Glioblastoma is 41-60 (52%) years, diffuse astrocytoma is 21-40 years 60.60 and Pilocytic Astrocytoma is 1-20 years (66.88). Glioblastoma, Anaplastic Astrocytoma and Diffuse astrocytoma are more common in male than female.

Conclusion: There is no gender difference in case of Pilocytic Astrocytoma.

Journal of National Institute of Neurosciences Bangladesh, 2020;6(2): 91-95

Downloads

Download data is not yet available.
Abstract
28
PDF
33

Downloads

Published

2020-12-13

How to Cite

Islam, M. N., Haq, N., Salam, M. B., Ahmed, M., Muhammad Ekramullah, S., Hossain, M. Z., Hossain, S. S., & Shirin, S. (2020). Frequency and Topography of AstrocyticTumor: Experience of 567 Cases at Referral Neuroscience Hospital in Bangladesh. Journal of National Institute of Neurosciences Bangladesh, 6(2), 91–95. https://doi.org/10.3329/jninb.v6i2.50748

Issue

Vol. 6 No. 2 (2020)

Section

Original Research Articles

License

Copyright on any research article in the Journal of National Institute of Neurosciences Bangladesh is retained by the author(s).

The authors grant the National Institute of Neurosciences Bangladesh a license to publish the article and identify itself as the original publisher.

Articles in the Journal of National Institute of Neurosciences Bangladesh are Open Access articles published under the Creative Commons CC BY-NC License (https://creativecommons.org/licenses/by-nc/4.0/)

This license permits use, distribution and reproduction in any medium, provided the original work is properly cited, and it is not used for commercial purposes.