Common Risk Factors Responsible for Acute Kidney Injury among Children: Experience at Medical University in Bangladesh

Authors

  • Sharmin Akter Luna Post-Graduate on Paediatric Nephrology, Department of Paedatric Nephrology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
  • Jakia Sultana Registrar, Department of Paediatrics, Shaheed Ziaur Rahman Medical College, Bogura, Bangladesh
  • Abdullah Al Mamun Assistant Professor, Department of Paediatric Nephrology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
  • Afroza Begum Associate Professor, Department of Paediatric Nephrology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
  • Md Habibur Rahman Professor & Ex. Chairman, Department of Paediatric Nephrology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
  • Ranjit Ranjan Roy Professor & Chairman, Department of Paediatric Nephrology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh

DOI:

https://doi.org/10.3329/jninb.v7i1.54751

Keywords:

Risk Factors; Acute Kidney Injury; Children

Abstract

Background: Acute kidney injury can occur among the younger children due to different reasons.

Objective: The purpose of the present study was to find out the risk factors and primary disease responsible for acute kidney injury among younger children.

Methodology: This cross-sectional study was conducted in the Department of Paediatric Nephrology with the collaboration of Paediatric Gastroenterology, Paediatric Neurology, Paediatric Neonatology and Microbiology and Immunology at Bangabandhu Sheikh Mujib University, Dhaka, Bangladesh from May 2018 to July 2019 for a period of one year. Patients with the age group of 1 month to 17 years who were at risk of AKI, and admitted in the inpatient department of Pediatrics and allied at Bangabandhu Sheikh Mujib University, Dhaka, Bangladesh in both sexes were selected as study population. To detect AKI, serum creatinine was measured at 0 h (baseline), 48 h and 5th day respectively.

Result: A total number of 42 patients, who fulfilled the inclusion criteria were enrolled in this study. The risk factors of AKI was mainly pre renal in 60% (n=9) cases, mostly due to nephrotoxic drugs followed by hypovolemia. Renal causes were in 40% (n=6) cases. Among these 50% cases due to amikacin and 50% cases due to use of radiocontrast agent. Most patients were with renal disease which was 30(58%) cases. Among them 28(93.0%) cases were nephrotic syndrome and 2(7.0%) cases were hydronephrosis. However, 7(13%) cases were cardiac disease presented with congenital heart disease who used radiocontrast agent.

Conclusion: In conclusion most common risk factors of acute kidney injury among younger children is pre-renal causes which are due to nephrotoxic drugs.

Journal of National Institute of Neurosciences Bangladesh, January 2021, Vol. 7, No. 1, pp. 42-46

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Published

2021-01-01

How to Cite

Luna, S. A., Sultana, J., Mamun, A. A., Begum, A., Rahman, M. H., & Roy, R. R. (2021). Common Risk Factors Responsible for Acute Kidney Injury among Children: Experience at Medical University in Bangladesh. Journal of National Institute of Neurosciences Bangladesh, 7(1), 42–46. https://doi.org/10.3329/jninb.v7i1.54751

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Section

Original Research Articles