Comparison of Laboratory Profiles of Cerebrospinal Fluid among Bacterial and Viral Meningitis Patients

Authors

  • Umme Habiba Assistant Professor, Department of Microbiology, Shaheed Suhrawardy Medical College, Dhaka, Bangladesh
  • Md Akram Hossain Senior Consultant (Microbiology), Imperial Hospital Limited, Chattogram, Bangladesh
  • Md Chand Mahmud Professor & Head, Department of Microbiology, President Abdul Hamid Medical College, Kishoreganj, Bangladesh
  • Md Sirajul Islam Bhuiyan Assistant Professor (Pediatrics), Mugda Medical College, Dhaka, Bangladesh
  • Md Ali Abdullah Rafique Senior Consultant and Head, Department of Clinical Pathology, Uttara Adhunik Medical College and Hospital, Dhaka, Bangladesh
  • Safia Sultana Associate Professor, Department of Microbiology, Shaheed Syed Nazrul Islam Medical College, Kishoreganj, Bangladesh

DOI:

https://doi.org/10.3329/jninb.v7i1.54757

Keywords:

Comparison; laboratory profiles; cerebrospinal fluid; bacterial meningitis; viral meningitis; meningitis

Abstract

Background: Laboratory profiles are important markers for the detection of meningitis.

Objective: The purpose of the present study was to compare of laboratory profiles of cerebrospinal fluid among bacterial and viral meningitis patients.

Methodology: This cross sectional study was carried out in the Department of Microbiology at Mymensingh Medical College, Mymensingh, Bangladesh from July 2010 to January 2012 for around 2 years. Clinically suspected patients with meningitis from paediatrics wards of MMCH, Mymensingh, Bangladesh were included in this study. On the basis of cytological tests and biochemical tests of CSF the study subjects were categorized into three groups, which were identified as bacterial meningitis, viral meningitis and normal CSF. After collection of CSF, physical examination, routine bed side culture and appropriate biochemical tests were performed. Tests for protein and glucose of CSF specimens were performed.

Result: A total 115 clinically and laboratory confirmed meningitis patients were enrolled in this study. The most of the cases of study population were in the age group 1 month to 5 years 97(84.3%) cases. Regarding the physical findings of CSF, purulent was found 21(60.0%) cases in bacterial meningitis and 14 (40.0%) cases were slightly turbid. The mean with SD of total count of WBC was higher in bacterial meningitis (1623.1±1708.06/mm3) than viral meningitis (56.0±73.83/mm3) (p=<0.001). Again the mean with SD of glucose was lowest in bacterial meningitis which was 21.0±9.77 mg/dL followed by viral meningitis which was 63.6±20.22 mg/dL. (p<0.001). Considering protein of CSF the mean with SD was highest in bacterial meningitis which was 242.8±188.09 mg/dL followed by viral meningitis which was 69.6±84.67mg/dL (p<0.001).

Conclusion: In conclusion the WBC count, CSF glucose and protein are significantly differ in bacterial and viral meningitis.

Journal of National Institute of Neurosciences Bangladesh, January 2021, Vol. 7, No. 1, pp. 69-74

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Published

2021-01-01

How to Cite

Habiba, U., Hossain, M. A., Mahmud, M. C., Bhuiyan, M. S. I., Rafique, M. A. A., & Sultana, S. (2021). Comparison of Laboratory Profiles of Cerebrospinal Fluid among Bacterial and Viral Meningitis Patients. Journal of National Institute of Neurosciences Bangladesh, 7(1), 69–74. https://doi.org/10.3329/jninb.v7i1.54757

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Section

Original Research Articles