Prevalence and Resistance Profile of Acinetobacter baumannii Isolated from Clinical Specimens at a Tertiary Care Hospital in Bangladesh

Authors

  • Bhuiyan Mohammad Mahtab Uddin Assistant Professor, Department of Microbiology, Enam Medical College, Savar, Dhaka, Bangladesh
  • Faria Akhand Medical Officer, Upazila Health Complex, Islampur, Jamalpur, Bangladesh
  • Sumia Bari Associate Professor Department of Gynaecology and Obstetrics, Enam Medical College, Savar, Dhaka, Bangladesh
  • Surovi Era Suchi Associate Professor, Department of Microbiology, Ad-din Sakina Women’s Medical College, Jessore, Bangladesh
  • Ritu Saha Associate Professor Department of Microbiology, Bashundhara Ad-din Medical College, Dhaka, Bangladesh
  • Mejbah Uddin Ahmed Professor, Department of Microbiology, Enam Medical College, Savar, Dhaka, Bangladesh

DOI:

https://doi.org/10.3329/jninb.v7i2.58117

Keywords:

Acinetobacter baumannii; antibiogram; antimicrobial resistance

Abstract

Background: Acinetobacter baumannii is one of the significant pathogens to cause healthcare-associated infections worldwide. It is difficult to control and the infections caused by it are difficult to treat, because it is multidrug resistant.

Objective: This study was conducted to determine the prevalence and antimicrobial resistance pattern of Acinetobacter baumannii at Dhaka Medical College Hospital, Dhaka, Bangladesh over a 12 months period.

Methodology: This retrospective study was carried out over a period of one year from July 2014 to June 2015 in the department of Microbiology at Dhaka Medical College Hospital, Dhaka, Bangladesh. Antimicrobial susceptibility testing of the isolates was performed by the disk diffusion method as recommended by Clinical Laboratory and Standards Institute CLSI.

Results: Non duplicate 28 A. baumannii were isolated out of a total 191 pathogenic Gram negative isolates (14.66% prevalence). The most frequently isolated A. baumannii was from ICU patients (75%) followed by inpatients (18%) and outpatients (7%). Most of the isolates were recovered from tracheal aspirates (75%). The resistance rates were higher than most of the internationally reported levels. Cephalosporins, aminoglycosides, fluoroquinolones and even carbapenems are becoming practically ineffective, where the colistin elicited the highest susceptibility levels.

Conclusion: This study has guided the empirical therapy and suggest that surveillance of antimicrobial resistance of Acinetobacter baumannii is necessary.

Journal of National Institute of Neurosciences Bangladesh, July 2021, Vol. 7, No. 2, pp. 177-180  

Downloads

Download data is not yet available.
Abstract
48
PDF
57

Downloads

Published

2022-02-06

How to Cite

Mahtab Uddin, B. M. ., Akhand, F., Bari, S. ., Suchi, S. E. ., Saha, R. ., & Ahmed, M. U. . (2022). Prevalence and Resistance Profile of Acinetobacter baumannii Isolated from Clinical Specimens at a Tertiary Care Hospital in Bangladesh. Journal of National Institute of Neurosciences Bangladesh, 7(2), 177–180. https://doi.org/10.3329/jninb.v7i2.58117

Issue

Vol. 7 No. 2 (2021)

Section

Original Research Articles

License

Copyright (c) 2022 Bhuiyan Mohammad Mahtab Uddin, Faria Akhand, Sumia Bari, Surovi Era Suchi, Ritu Saha, Mejbah Uddin Ahmed

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Copyright on any research article in the Journal of National Institute of Neurosciences Bangladesh is retained by the author(s).

The authors grant the National Institute of Neurosciences Bangladesh a license to publish the article and identify itself as the original publisher.

Articles in the Journal of National Institute of Neurosciences Bangladesh are Open Access articles published under the Creative Commons CC BY-NC License (https://creativecommons.org/licenses/by-nc/4.0/)

This license permits use, distribution and reproduction in any medium, provided the original work is properly cited, and it is not used for commercial purposes.