Renal and Splenic Infarction: Unusual Manifestation of the Antiphospholipid Syndrome

Authors

  • Elizabeth F Daher Federal University of Ceara. Fortaleza, Ceara
  • Rafael S.A. Lima School of Medicine of Ribeirão Preto, University of São Paulo. Ribeirão Preto, São Paulo
  • Ana Cristina L. Melo General Hospital of Fortaleza. Fortaleza, Ceará
  • Geraldo B Silva Junior School of Medicine, Federal University of Ceara, Ceará

DOI:

https://doi.org/10.3329/jom.v14i2.19672

Keywords:

Antiphospholipid syndrome, renal infarction, splenic infarction

Abstract

Antiphospholipid syndrome is a multisystem disorder characterized by recurrent thromboses in the arterial system, venous system, or both. A 42-year-old man sought treatment reporting two episodes of abdominal pain in the right flank radiating to his back associated with nausea and vomiting fifteen days prior to admission. Abdominal CT with contrast showed left renal atrophy, renal right and splenic infarction. Laboratory tests showed worsening of renal function after CT contrast: serum creatinine 0.6mg/dL to 5.5mg/dL. The complementary investigation showed anti-cardiolipin antibodies (aCL) positive in high titers; antinuclear antibodies, myeloperoxidase-antineutrophil cytoplasmic antibody, anti-nuclear antibody, serology for hepatitis A, B and C, ELISA anti-HIV and VDRL were negative. A diagnosis of renal and splenic infarction due to antiphospholipid syndrome was made and the patient received treatment with subcutaneous heparin followed by warfarin.

DOI: http://dx.doi.org/10.3329/jom.v14i2.19672

J Medicine 2013, 14(2): 187-188

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Author Biographies

Elizabeth F Daher, Federal University of Ceara. Fortaleza, Ceara

Department of Internal Medicine

Rafael S.A. Lima, School of Medicine of Ribeirão Preto, University of São Paulo. Ribeirão Preto, São Paulo

Department of Internal Medicine

Ana Cristina L. Melo, General Hospital of Fortaleza. Fortaleza, Ceará

Division of Nephrology

Geraldo B Silva Junior, School of Medicine, Federal University of Ceara, Ceará

Department of Internal Medicine

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Published

2014-07-24

How to Cite

Daher, E. F., Lima, R. S., Melo, A. C. L., & Silva Junior, G. B. (2014). Renal and Splenic Infarction: Unusual Manifestation of the Antiphospholipid Syndrome. Journal of Medicine, 14(2), 187–188. https://doi.org/10.3329/jom.v14i2.19672

Issue

Vol. 14 No. 2 (2013)

Section

Case Reports

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