Peptic Ulcer Disease and Misuses of Ulcer Healing Drugs in a Tertiary Care Hospital in Dhaka City

Authors

  • Md. Hafiz Md. Hafiz Sardar Associate Professor (Medicine), Dhaka Medical College
  • Mohammad Murad Hossain Assistant Professor (Medicine), Dhaka Medical College, Dhaka
  • Khan Abul Kalam Azad Professor (Medicine), Dhaka Medical College, Dhaka
  • Md Uzzwal Mallik Lecturer, Forensic Medicine, Dhaka Medical College
  • Moumita Chakraborty Resident, Department of Medicine, Dhaka Medical College, Dhaka

DOI:

https://doi.org/10.3329/jom.v16i1.22386

Keywords:

Peptic ulcer disease, misuse of drugs, ulcer healing drugs

Abstract

This prospective cross sectional study was conducted in Dhaka Medical College Hospital, Dhaka during July, 2013 to December, 2013. Hundred patients were included in this study. Peptic ulcer disease, presented as upper abdominal pain is one of the common disease with a number of underlying causes. Prospective analyses of 100 patients with upper abdominal pain were studied at medicine units of Dhaka Medical College Hospital, Dhaka. Of these 36 patients belonged to peptic ulcer, 20 patients to irritable bowel syndrome and 22 patients to non-ulcer dyspepsia. Next in order were helminthiasis (5 patients), cholelithiasis (4 patients), gastric carcinoma (4 patients), liver abscess (5 patients) chronic pancreatitis (3 patients) and acute pancreatitis (1 patient). Mean age incidence in this series was 39.47 years. Male and female ratio was 1.54:1. Forty patients were smoker with male and female ratio of 3.44:1.All patients had presenting feature of upper abdominal pain. Commonest site of pain was in the epigastrium in 48.08% of cases.Pain was burning in 43.27% cases, periodic pain in 24.03%, and nocturnal hunger pain in 33.65% of cases.Relief of pain after taking food were observed in 38.46%. Epigastric tenderness was present in 56.73% patients.The diagnosis of peptic ulcer disease, irritable bowel syndrome and non-ulcer dyspepsia, the three leading causes of upper abdominal pain, were suspected by history and physical examination but it was difficult to interpret these on clinical ground alone .Some routine and some selected investigation were done for confirmatory diagnosis.

In this series, significant disparity detected between clinically diagnosed peptic ulcer diseases 90.38% and endoscopically confirmed peptic ulcer disease, 34.62% cases. As a consequence of wrong diagnosis of PUD, there are huge misuses of ulcer healing drugs and a great economic burden on patients (300 taka per month) and on the nation.

DOI: http://dx.doi.org/10.3329/jom.v16i1.22386

J MEDICINE 2015; 16 : 27-34

Downloads

Download data is not yet available.
Abstract
453
PDF
272

Downloads

Published

2015-02-24

How to Cite

Md. Hafiz Sardar, M. H., Hossain, M. M., Azad, K. A. K., Mallik, M. U., & Chakraborty, M. (2015). Peptic Ulcer Disease and Misuses of Ulcer Healing Drugs in a Tertiary Care Hospital in Dhaka City. Journal of Medicine, 16(1), 27–34. https://doi.org/10.3329/jom.v16i1.22386

Issue

Vol. 16 No. 1 (2015)

Section

Original Articles

License

Authors who publish with this journal agree to the following terms:

    1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

    1. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

  1. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).