Evans Syndrome

Authors

  • Ahmedul Kabir Assistant professor, Dept of Medicine, DMCH
  • Jayanta Banik Post-graduate trainee, Dept. of Medicine, BSMMU
  • Ratan Das Gupta Assistant professor, Dept of Medicine, DMCH
  • Robed Amin Assistant professor, Dept of Medicine, DMCH
  • AM Wasiq Faisal Medical Officer, Dept. of Medicine, DMCH
  • ASM Mafidul Islam Assistant Registrar, Dept. of Medicine, DMCH
  • Mostofa Kamal Registrar, Dept. of Medicine, DMCH
  • Pinaki Paul Associate Professor, Dept. of Medicine, DMCH
  • Faizul Islam Chowdhury Associate Professor, Dept. of Medicine, DMCH
  • Hasna Hena Parveen Medical Officer, Dept. of Medicine, DMCH

DOI:

https://doi.org/10.3329/jom.v11i1.4280

Keywords:

Evan's Syndrome, autoimmune haemolytic anaemia

Abstract

Evans' syndrome is a rare autoimmune disorder in which the body makes antibodies that destroy the red blood cells, platelets and white blood cells. Patients are diagnosed with thrombocytopenia and Coombs' positive haemolytic anaemia and have no other known underlying aetiology. We report two cases of autoimmune haemolytic anaemia (AIHA) associated with immune thrombocytopenia which is known as Evans's syndrome. In these patient there were clinical evidence of haemolysis, serum bilirubin was elevated, blood film showed anaemia with trrombocytopenia but no spherocytosis. Immunosuppression was achieved with steroid. We would like to highlight that a negative Coomb's test is now often interpreted as absence of autoantibodies, but it is more or less preclusive for the diagnosis of AIHA.

Keywords: Evan's Syndrome, autoimmune haemolytic anaemia

DOI:10.3329/jom.v11i1.4280

J Medicine 2010: 11: 78-82

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How to Cite

Kabir, A., Banik, J., Gupta, R. D., Amin, R., Faisal, A. W., Islam, A. M., Kamal, M., Paul, P., Chowdhury, F. I., & Parveen, H. H. (2010). Evans Syndrome. Journal of Medicine, 11(1), 78–82. https://doi.org/10.3329/jom.v11i1.4280

Issue

Vol. 11 No. 1 (2010)

Section

Case Reports

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