Association of Cardiovascular Disease with Micro Albuminuria in Type 2 Diabetes Mellitus - Study in A Tertiary Care Hospital

Authors

  • Md Jahirul Haque Associate Professor (CC), Medicine, Shaheed Syed Nazrul Islam Medical College, Kishoreganj, Bangladesh
  • Md Nazrul Islam Senior Consultant (Medicine), Narayanganj General Hospital, Narayanganj, Bangladesh
  • Md Zakaria Al Aziz Assistant Professor, Department of Medicine, Sheikh Hasina Medical College, Tangail, Bangladesh
  • Shah Mohammad Ashrafuzzaman Assistant Professor, Department of Medicine, Mymensingh Medical College, Mymensingh, Bangladesh
  • Gobindo Chandra Banik Associate Professor, Department of Medicine, Dhaka Medical College, Dhaka, Bangladesh
  • AKM Sajedur Rahman Assistant Professor, Department of Medicine, Cumilla Medical College, Cumilla, Bangladesh
  • Sarmistha Biswas Associate Professor, Department of Medicine, Dhaka Medical College, Dhaka, Bangladesh
  • HAM Nazmul Ahasan Professor of Medicine, Popular Medical College, Dhaka, Bangladesh

DOI:

https://doi.org/10.3329/jom.v21i2.50209

Keywords:

Type 2 Diabetes, Microalbuminuria, DM

Abstract

Introduction: Microalbuminuria appears to be the earliest sign and predictor of the subsequent diabetic renal disease and is a marker of increased cardiovascular morbidity and mortality. It is also a predictor of morbidity and mortality in patients who do not have evidence of significant renal disease

Objective: To evaluate the association of microalbuminuria in type 2 DM with cardiovascular diseases and to correlate microalbuminuria with age of onset in type 2 diabetes mellitus.

Materials and Method: A hospital based observational study was carried out in the Department of Medicine, Dhaka Medical College & Hospital,Dhaka, from January 2014 to November 2014. A total of 100 patients diagnosed as type 2 diabetes mellitus according to American Diabetic Association guideline were included in this study. Association of microalbuminuria with cardiovascular diseases was determined by statistical analysis and regression analysis.

Results: The majority (40.0%) of patients were in 5th decade and the mean (±SD) age was 57.17±11.2 years. According to BMI it is observed that majority of patients were obese in both groups, where male 66.0% and female 75.5%.The occurrence of cardiovascular diseases in type 2 diabetes mellitus patients is increasing with duration of DM, where 61.9% found in newly diagnosed DM. It was observed that 38(38.0%) patients had normoalbuminuria (<30 mg/gm), their mean ACR was 17.6±8.1 mg/gm and 62(62.0%) patients had microalbuminuria (30-300 mg/gm), their mean ACR was 158.7±88.3 mg/gm. Microalbuminuria was found 53(67.1%) and 9(42.9%) patients with cardiovascular diseases and without cardiovascular diseases respectively. Occurrence of microalbuminuia was found significantly higher (p<0.05) in type 2 DM patients with cardiovascular diseases.

Conclusion:Microalbuminuria is found strongly associated with cardiovascular diseases in type 2 diabetes mellitus patients and there is 2.72 times more chance of developing cardiovascular diseases.

J MEDICINE JUL 2020; 21 (2) : 76-81

Downloads

Download data is not yet available.
Abstract
34
PDF
47

Downloads

Published

2020-11-09

How to Cite

Haque, M. J., Islam, M. N., Aziz, M. Z. A., Ashrafuzzaman, S. M., Banik, G. C., Rahman, A. S., Biswas, S., & Ahasan, H. N. (2020). Association of Cardiovascular Disease with Micro Albuminuria in Type 2 Diabetes Mellitus - Study in A Tertiary Care Hospital. Journal of Medicine, 21(2), 76–81. https://doi.org/10.3329/jom.v21i2.50209

Issue

Vol. 21 No. 2 (2020)

Section

Original Articles

License

Authors who publish with this journal agree to the following terms:

    1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

    1. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

  1. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).