SARS-CoV-2 Infection and Risk Stratification among Healthcare Workers in the Largest COVID-19 Dedicated Tertiary Care Hospital in Dhaka, Bangladesh

Authors

  • Md Uzzwal Mallik Assistant Professor, Department of Medicine, Dhaka Medical College, Dhaka, Bangladesh
  • Reaz Mahmud Assistant Professor, Department of Neuromedicine, Dhaka Medical College, Dhaka, Bangladesh
  • Saima Azad Indoor Medical Officer, Department of Medicine, Dhaka Medical College Hospital, Dhaka, Bangladesh
  • - Md Moniruzzaman Medical Officer, National Institute of Neuroscience and Hospital, Dhaka, Bangladesh
  • Tahera Khatun Indoor Medical Officer, Department of Medicine, Dhaka Medical College Hospital, Dhaka, Bangladesh
  • Mohammad Rafiquzzaman Indoor Medical Officer, Department of Medicine, Dhaka Medical College Hospital, Dhaka, Bangladesh
  • Sonjoy Kumar Poddar Indoor Medical Officer, Department of Medicine, Dhaka Medical College Hospital, Dhaka, Bangladesh
  • Mohammad Mahfuzul Hoque Assistant Professor, Department of Medicine, Dhaka Medical College, Dhaka, Bangladesh
  • Md Titu Miah Professor, Department of Medicine, Dhaka Medical College, Dhaka, Bangladesh
  • Md Mujibur Rahman Professor, Department of Medicine, BSM Medical University, Dhaka, Bangladesh

DOI:

https://doi.org/10.3329/jom.v23i1.57930

Keywords:

Health care worker, SARS-CoV-2 infection, COVID-19

Abstract

Background: The health care workers’(HCWs) are working 24/7 in managing devastating pandemicCorona virus disease19(COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) as front liner which leads them to be at highest risk for contacting infection. In Bangladesh, beinga lower middle-income country and densely populated, the burden is much more on HCWs.

Methods: We did a cross-sectional study with an aim to identify the prevalence, risk factors, and outcomesof SARS-CoV-2 infection among the HCWs in a COVID-19 dedicated tertiary care hospital. Statisticalanalysis was done in SPSS version-26. Multivariate regression analysis was done to evaluate risk factorsresponsible for COVID-19 infection and the severity of the COVID-19 disease. We expressed odds ratiowith 95% CI, and considered the p-value of <0.05 as significant in the two-tailed test.

Results: A total of 864 HCWs had participated with mean age of 34.16 ± 6.77 and 426 (49.31%) males.Among them 143 (16.55%) were tested RT-PCR positive for SARS-COV-2. Bronchial asthma/COPD andHypertension were the most common co-morbidities with 23 (16.08%) for each. About 102 (71.33%) ofthe RT-PCR positive HCWs became symptomatic. Fever, cough and myalgia were the most commonsymptoms 84(82.35%), 67(65.69%) and 52(50.98%) respectively.Multivariate regression analysis revealed hypertension, gout, and working in the COVID-19 confirmedward had a significant odds ratio for getting infected with SARS-CoV-2 [95% CI, p-value 1.91 (1.08 - 3.41),0.027; 5.85 (1.33 - 25.74), 0.020; and 1.83 (1.10 - 3.03), 0.019].Bronchial asthma/COPD and gout found to be risk factors for moderate to severe COVID-19 disease[95% CI, p-value 3.04 (1.01 - 9.21), 0.049 and 23.38 (3.42 - 159.72), 0.001]. Hospitalization rate was12(85.7%), and 3(100%) and median hospital stays were 11 (5.5 - 15), and 20 (7 - 30) days for moderate andsevere diseases respectively. Outcome was uneventful without any ICU admission and death.

Conclusion: HCWs working in the COVID-19 confirmed ward are at increased risk of infection withSARS-COV-2. Some co-morbidities like hypertension and gout are important risk factors for contactingSARS-COV-2 infection. Bronchial asthma/COPD and gout favors disease severity.

J MEDICINE 2022; 23: 5-12

Downloads

Download data is not yet available.
Abstract
5
PDF
3

Downloads

Published

2022-02-03

How to Cite

Mallik, M. U., Mahmud, R. ., Azad, S. ., Md Moniruzzaman, .-., Khatun, T. ., Rafiquzzaman, M. ., Poddar, S. K. ., Hoque, M. M. ., Miah, M. T. ., & Rahman, M. M. . (2022). SARS-CoV-2 Infection and Risk Stratification among Healthcare Workers in the Largest COVID-19 Dedicated Tertiary Care Hospital in Dhaka, Bangladesh. Journal of Medicine, 23(1), 5–12. https://doi.org/10.3329/jom.v23i1.57930

Issue

Vol. 23 No. 1 (2022)

Section

Original Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Authors who publish with this journal agree to the following terms:

    1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

    1. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

  1. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).