Assessment of Frequency of Polypharmacy along with its Relation to Dementia and Drug Adherence among Admitted Geriatric Patients in Medicine Wards of a Tertiary Care Hospital

Authors

  • Ummay Fatema Khatun Assistant Professor (Medicine), Chattogram Medical College, Chattogram
  • Subrata Dey Registrar (Medicine), Chittagong Medical College, Chattogram
  • Sujat Paul Professor (Medicine), Chattogram Medical College, Chattogram
  • Sheikh Khairul Kabir Assistant Professor (Medicine), Chattogram Medical College, Chattogram
  • Aparna Dev Registrar (Medicine), Chittagong Medical College, Chattogram

DOI:

https://doi.org/10.3329/jom.v24i1.64897

Keywords:

Polypharmacy, Elderly, Non-adherence, Dementia, chronic health conditions

Abstract

Background: Polypharmacy has been associated with adverse drug reactions, medication errors and non- adherence to prescribe drugs and geriatric population is more prone to this condition. On the other hand, dementia is a major concern among growing chronic diseases in the ageing society and its assessment has not been adequately done in our setting.

Method: One hundred subjects aged more≥60 years were included in this analytical cross-sectional from the Medicine Department of Chattogram Medical College Hospital from November 2018 to April 2019. A structured case record form collected data, and drug adherence were measured by Morisky Medication Adherence Scale-8 (MMAS-8). PP was defined as intake of e”5 drugs. Cognitive impairment was classified as presence or absence of dementia by Mini-cog tool.

Results: The average age of individuals was 65.56±6.9 years and 62 were men. The prevalence of polypharmacy, dementia, and drug non-adherence was respectively, 56%, 47%, and 49%. Patients with polypharmacy were more likely to be non-adherent (odds ratio: 2.4; 95% CI: 1.1-5.4; p=0.039) and demented (odds ratio: 3.38; 95% CI: 1.1-11.8; p=0.019) than the elderly patients without polypharmacy.

Conclusion: As there is significant association between polypharmacy with dementia and drug nonadherence, judicious use of drugs is mandatory to reduce these risk.

J MEDICINE 2023; 24: 3-9

Downloads

Download data is not yet available.
Abstract
48
PDF
57

Downloads

Published

2023-03-22

How to Cite

Khatun, U. F. ., Dey, S. ., Paul, S. ., Kabir, S. K. ., & Dev, A. . (2023). Assessment of Frequency of Polypharmacy along with its Relation to Dementia and Drug Adherence among Admitted Geriatric Patients in Medicine Wards of a Tertiary Care Hospital. Journal of Medicine, 24(1), 3–9. https://doi.org/10.3329/jom.v24i1.64897

Issue

Vol. 24 No. 1 (2023)

Section

Original Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Authors who publish with this journal agree to the following terms:

    1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

    1. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

  1. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).