Assessment of Frequency of Polypharmacy along with its Relation to Dementia and Drug Adherence among Admitted Geriatric Patients in Medicine Wards of a Tertiary Care Hospital

Authors

  • Ummay Fatema Khatun Assistant Professor (Medicine), Chattogram Medical College, Chattogram
  • Subrata Dey Registrar (Medicine), Chittagong Medical College, Chattogram
  • Sujat Paul Professor (Medicine), Chattogram Medical College, Chattogram
  • Sheikh Khairul Kabir Assistant Professor (Medicine), Chattogram Medical College, Chattogram
  • Aparna Dev Registrar (Medicine), Chittagong Medical College, Chattogram

DOI:

https://doi.org/10.3329/jom.v24i1.64897

Keywords:

Polypharmacy, Elderly, Non-adherence, Dementia, chronic health conditions

Abstract

Background: Polypharmacy has been associated with adverse drug reactions, medication errors and non- adherence to prescribe drugs and geriatric population is more prone to this condition. On the other hand, dementia is a major concern among growing chronic diseases in the ageing society and its assessment has not been adequately done in our setting.

Method: One hundred subjects aged more≥60 years were included in this analytical cross-sectional from the Medicine Department of Chattogram Medical College Hospital from November 2018 to April 2019. A structured case record form collected data, and drug adherence were measured by Morisky Medication Adherence Scale-8 (MMAS-8). PP was defined as intake of e”5 drugs. Cognitive impairment was classified as presence or absence of dementia by Mini-cog tool.

Results: The average age of individuals was 65.56±6.9 years and 62 were men. The prevalence of polypharmacy, dementia, and drug non-adherence was respectively, 56%, 47%, and 49%. Patients with polypharmacy were more likely to be non-adherent (odds ratio: 2.4; 95% CI: 1.1-5.4; p=0.039) and demented (odds ratio: 3.38; 95% CI: 1.1-11.8; p=0.019) than the elderly patients without polypharmacy.

Conclusion: As there is significant association between polypharmacy with dementia and drug nonadherence, judicious use of drugs is mandatory to reduce these risk.

J MEDICINE 2023; 24: 3-9

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Published

2023-03-22

How to Cite

Khatun, U. F. ., Dey, S. ., Paul, S. ., Kabir, S. K. ., & Dev, A. . (2023). Assessment of Frequency of Polypharmacy along with its Relation to Dementia and Drug Adherence among Admitted Geriatric Patients in Medicine Wards of a Tertiary Care Hospital. Journal of Medicine, 24(1), 3–9. https://doi.org/10.3329/jom.v24i1.64897

Issue

Vol. 24 No. 1 (2023)

Section

Original Articles

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