Clinical Characteristics of Deceased with COVID-19 Infection: Data from the Largest COVID-19 Dedicated Hospital in Bangladesh

Authors

  • Mohammad Mahfuzul Hoque Department of Medicine, Dhaka Medical College, Bangladesh
  • Reaz Mahmud Department of Neurology, Dhaka Medical College, Bangladesh
  • Ponkaj Kanti Datta Department of Medicine, Dhaka Medical College, Bangladesh
  • Ejrarul Alam Khan Department of Medicine, Dhaka Medical College, Bangladesh
  • Sarmistha Biswas Department of Medicine, Dhaka Medical College, Bangladesh
  • Kamolesh Chandra Basu Department of Medicine, Dhaka Medical College, Bangladesh
  • Mohammed Masudul Hassan Khan Department of Medicine, Dhaka Medical College, Bangladesh
  • Muhammad Faizur Rahman Department of Medicine, Dhaka Medical College, Bangladesh
  • Md Uzzwal Mallik Department of Medicine, Dhaka Medical College, Bangladesh
  • Mirza Mohammad Asif Adnan Department of Medicine, Dhaka Medical College, Bangladesh
  • Imran Mahmud Department of Medicine, Dhaka Medical College, Bangladesh
  • Md Arman Hossain Department of Medicine, Dhaka Medical College, Bangladesh
  • Nazia Binte Ali Maternal and Child Health Division, International Centre for Diarrhoeal Disease Research, Bangladesh #Current Address: Department of Medicine, Bangabandhu Sheikh Mujib Medical University, Bangladesh
  • Md Khairul Islam Department of Medicine, Dhaka Medical College, Bangladesh
  • Md Titu Miah Department of Medicine, Dhaka Medical College, Bangladesh
  • Md Mujibur Rahman Department of Medicine, Dhaka Medical College, Bangladesh

DOI:

https://doi.org/10.3329/jom.v24i1.64901

Keywords:

COVID-19, Clinical Characteristics

Abstract

The death toll of the coronavirus disease 2019 (COVID-19) has been considerable. Several risk factors have been linked to mortality due to COVID-19 in hospitals. This study aimed to describe the clinical characteristics of patients who either died from COVID-19 at Dhaka Medical College Hospital in Bangladesh. In this retrospective study, we reviewed the hospital records of patients who died or recovered and tested positive for COVID-19 from May 3 to August 31, 2020. All patients who died during the study period were included in the analysis. A comparison group of patients who survived COVID-19 at the same hospital during the same period was systematically sampled. All available information was retrieved from the records, including demographic, clinical, and laboratory variables. Of the 3115 patients with confirmed COVID-19 during the study period, 282 died. The mean age of patients who died was higher than that of those who survived (56.7 vs 52.6 years). Approximately three-fourths of deceased patients were male. History of smoking (risk ratio 2.3; 95% confidence interval: 1.6–3.4), comorbidities (risk ratio: 1.5; 95% confidence interal:1.1–2.1), chronic kidney disease (risk ratio: 3.2; 95% confidence interval: 1.7–6.25), and ischemic heart disease (risk ratio:1.8; 95% confidence interval: 1.1–2.9) were higher among the deceased than among those who survived. Mean C-reactive protein and D-dimer levels [mean (interquartile range), 34 (21–56) vs. 24 (12–48); and D-dimer [1.43 (1–2.4) vs. 0.8 (0.44–1.55)] were higher among those who died than among those who recovered. Older age, male sex, rural residence, history of smoking, and chronic kidney disease were found to be important predictors of mortality. Early hospitalization should be considered for patients with COVID-19 who are older, male, and have chronic kidney disease. Rapid referral to tertiary care facilities is necessary for high-risk patients in rural settings

J MEDICINE 2023; 24: 28-36

Downloads

Download data is not yet available.
Abstract
60
PDF
65

Downloads

Published

2023-03-22

How to Cite

Hoque, M. M. ., Mahmud, R. ., Datta, P. K. ., Khan, E. A. ., Biswas, S. ., Basu, K. C. ., Khan, M. M. H. ., Rahman, M. F. ., Mallik, M. U. ., Adnan, M. M. A. ., Mahmud, I. ., Hossain, M. A. ., Ali, N. B. ., Islam, M. K. ., Miah, M. T. ., & Rahman, M. M. . (2023). Clinical Characteristics of Deceased with COVID-19 Infection: Data from the Largest COVID-19 Dedicated Hospital in Bangladesh. Journal of Medicine, 24(1), 28–36. https://doi.org/10.3329/jom.v24i1.64901

Issue

Vol. 24 No. 1 (2023)

Section

Original Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Authors who publish with this journal agree to the following terms:

    1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

    1. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

  1. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).