A Young Lady with Quadriparesis

Authors

  • Ayesha Siddiqua Resident Physician of Medicine, Popular Medical College Hospital, Dhaka
  • Ruhul Quddus Assistant Professor, National Institute of Neuroscience & Hospital, Dhaka
  • Homayra Tahseen Associate Professor, Popular Medical College Hospital, Dhaka
  • Sharmin Akter Assistant Registrar, Popular Medical College Hospital, Dhaka

DOI:

https://doi.org/10.3329/jom.v24i2.67281

Keywords:

Young Lady, NMOSD, AQP4-IgG

Abstract

Neuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune disease, causing multifocal CNS inflammation affecting the optic nerves & spinal cord. In the 20th century, ‘Devics disease’ was considered as a variant of Multiple sclerosis(MS) that spared the brain. However, the discovery of IgG-class antibodies that bind to the water channel aquaporin-4 (AQP4-IgG) in serum from patients with Devic’s disease, but not from those with typical MS, established NMO as a distinct entity with a chronic, relapsing course. Our patient, a 42-year-old woman has been suffering from vomiting for 2 months followed by inability to move all extremities for last 7 days. It was the very 1st episode of such type of illness. We are reporting this case to highlight the presentation of NMOSD, which is itself a rare disease, outcropped as ‘Area postrema syndrome’, an inaugural manifestation in this patient.

J MEDICINE 2023; 24(2): 158-161

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Published

2023-07-02

How to Cite

Siddiqua, A., Quddus, R. ., Tahseen, H. ., & Akter, S. (2023). A Young Lady with Quadriparesis. Journal of Medicine, 24(2), 158–161. https://doi.org/10.3329/jom.v24i2.67281

Issue

Section

Case Reports