Pattern of Macrovascular Complications and its relationship with HbA1c in Hospitalized Patients with Type 2 Diabetes Mellitus

Authors

  • Miftahul Jannat Registrar of Medicine, Ahsania Mission Cancer and general Hospital, Dhaka, Bangladesh.
  • Mahbub Mayukh Rishad Assistant professor, dept of Medicine, Popular Medical College & Hospital(PMCH)
  • Nawsabah Noor Assistant professor, dept of Medicine, Popular Medical College & Hospital(PMCH)
  • S M Kawser Zafor Prince Department of Community Health & Epidemiology, and Department of Pharmacy, Faculty of Medicine, Dalhousie University, Halifax, NS, Canada
  • Tazbiha Rahman Khan Lecturer, Department of Biochemistry, Popular Medical College, Dhaka, Bangladesh
  • Najeeb Mahiyuddin Registrar of Medicine, Popular Medical College, Dhaka, Bangladesh
  • Md Abdul Jalil Ansari Ex Professor and Head, Department of Endocrinology, Dhaka Medical College, Dhaka, Bangladesh

DOI:

https://doi.org/10.3329/jom.v25i2.74310

Keywords:

Type 2 Diabetes Mellitus, Macrovascular Complications, HbA1c, Myocardial Infarction, Glycemic Control, Peripheral Vascular Disease

Abstract

Background: Type 2 diabetes is a common metabolic disorder causing high blood sugar due to insulin resistance and relative insulin deficiency. It poses a significant global health burden, especially in low and middle-income countries. This study explores how well-controlled blood sugar (HbA1c) affects the types and patterns of complications in hospitalized patients with type 2 diabetes. Methods: Conducted over six months at a tertiary care hospital, this cross-sectional study included 200 men and women with T2DM. Data were collected through evaluations and documented. Macrovascular complications were identified using specific criteria: elevated cardiac troponin I for myocardial infarction, neurological deficits with imaging for stroke, and foot ulcers or amputation history for peripheral vascular disease. Results: Macrovascular complications were found in 33% of patients, with myocardial infarction being the most common (48.5%), followed by stroke (37.9%) and peripheral vascular disease (13.6%). Patients with complications had significantly higher HbA1c and blood glucose levels. Conclusion: A significant proportion of hospitalized T2DM patients have macrovascular complications, associated with higher HbA1c levels. These findings emphasize the importance of good glycemic control to prevent such complications.

J MEDICINE 2024; 25: 136-140

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Published

2024-07-16

How to Cite

Jannat, M. ., Rishad, M. M., Noor, N. ., Prince, S. M. K. Z., Khan, T. R. ., Mahiyuddin, N. ., & Ansari, M. A. J. (2024). Pattern of Macrovascular Complications and its relationship with HbA1c in Hospitalized Patients with Type 2 Diabetes Mellitus. Journal of Medicine, 25(2), 136–140. https://doi.org/10.3329/jom.v25i2.74310

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Original Articles