Evaluation of Hematological Changes in Dengue Fever: experience of 2023 outbreak from Jashore, Bangladesh

Authors

  • Tosdikur Rahman Khan Assistant Registrar, Department of Medicine, Jashore Medical College Hospital, Bangladesh
  • Goutam Kumar Acherjya Associate Professor, Department of Medicine, Jashore Medical College Hospital, Bangladesh
  • Jahangir Hossain Assistant Professor, Department of Medicine, Jashore Medical College Hospital, Bangladesh
  • Selim Reza Assistant Professor, Department of Transfusion Medicine, Jashore Medical College Hospital, Bangladesh
  • Tahera Nasrin Consultant, Department of Paediatrics, Ibn Sina Hospital and Diagnostic Centre, Jashore, Bangladesh.

DOI:

https://doi.org/10.3329/jom.v26i1.78995

Keywords:

Dengue, Fever, Platelet, Hematological changes

Abstract

Background: Dengue fever is a painful febrile illness caused by a mosquito-borne Arbovirus. Epidemic episodes often occur during the rainy season. Complete blood count (CBC) is essential in patients with dengue fever and serological tests are necessary to confirm it. This study aimed to evaluate the hematological changes in dengue fever patients in Jashore Medical College Hospital, Bangladesh. Methods: This prospective cross-sectional study was conducted in the Department of Medicine, Jashore Medical college Hospital, Bangladesh from July 2023 to Decembar 2023. The study involved 177 dengue fever patients identified through NS1 and/or IgM antibody tests. Purposive sampling was used for patient selection, and data analysis utilized SPSS version 23.0. Results: Analysis of hematological parameters on the 1st and 3rd days indicated significant shifts in platelet, leucocyte, neutrophil, and lymphocyte counts. Platelet count decreased from 99.67±96.17 x 109/L to 82.72±60.84 x 109/L (p=0.048). Leucocyte count rose from 6.43±3.01 x 109/L to 7.85±5.58 x 109/L (p=0.003), while neutrophil count decreased from 6.31±1.38 x 109/L to 5.44±1.36 x 109/L (p<0.001). Lymphocyte count also increased from 3.06±1.80 x 109/L to 3.78±1.19 x 109/L (p<0.001). No significant shifts were observed in hemoglobin (p=0.579) or hematocrit (p=0.639) levels. Conclusion: Among dengue fever patients, platelet and neutrophil counts decrease while leukocyte and lymphocyte counts increase significantly between the 1st and 3rd days. However, there are no significant shifts observed in hemoglobin or hematocrit levels in the same tenure.

J MEDICINE 2025; 26: 43-47

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Published

2025-02-23

How to Cite

Khan, T. R., Acherjya, G. K., Hossain, J., Reza, S., & Nasrin, T. (2025). Evaluation of Hematological Changes in Dengue Fever: experience of 2023 outbreak from Jashore, Bangladesh . Journal of Medicine, 26(1), 43–47. https://doi.org/10.3329/jom.v26i1.78995

Issue

Vol. 26 No. 1 (2025)

Section

Original Articles

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