A Benzofuranone from the Flowers of Nyctanthes arbortristis and its Antibacterial and Cytotoxic Activities

Authors

  • Naznin Ara Khatune Department of Pharmacy, University of Rajshahi, Rajshahi 6205
  • M Asik Mossadik Department of Pharmacy, University of Rajshahi, Rajshahi 6205
  • M Mukhlesur Rahman Department of Pharmacy, University of Rajshahi, Rajshahi 6205
  • Proma Khondkar Department of Pharmacy, University of Rajshahi, Rajshahi 6205
  • M Ekramul Haque mukhlesurrah@yahoo.co.uk
  • Alexander I Gray Department of Pharmaceutical Sciences, University of Strathclyde, SIBS Building, 27 Taylor Street, Glasgow G4 ONR, Scotland, UK

DOI:

https://doi.org/10.3329/dujps.v4i1.191

Keywords:

Nyctanthes arbortristis, Nyctantheceae, 3, 3a, 7, 7a-tetrahydro-3a-hydroxy-6(2H)-benzofuranone, Antibacterial, Cytotoxicity

Abstract

A benzofuranone, 3,3a,7,7a-tetrahydro-3a-hydroxy-6(2H)-benzofuranone (1), was isolated from the flower of Nyctanthes arbortristis Linn. The compound was identified by 1D and 2D NMR and MS analyses. It showed significant antibacterial activity against both Gram positive and Gram negative bacteria. The LC50 of the compound was found to be 8.73 mg/ml in brine shrimp lethality bioassay. Key words: Nyctanthes arbortristis, Nyctantheceae; 3,3a,7,7a-tetrahydro-3a-hydroxy-6(2H)-benzofuranone, Antibacterial, Cytotoxicity Dhaka Univ. J. Pharm. Sci. Vol.4(1) 2005 The full text is of this article is available at the Dhaka Univ. J. Pharm. Sci. website

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Abstract
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How to Cite

Khatune, N. A., Mossadik, M. A., Rahman, M. M., Khondkar, P., Haque, M. E., & Gray, A. I. (2007). A Benzofuranone from the Flowers of Nyctanthes arbortristis and its Antibacterial and Cytotoxic Activities. Dhaka University Journal of Pharmaceutical Sciences, 4(1). https://doi.org/10.3329/dujps.v4i1.191

Issue

Vol. 4 No. 1 (2005)

Section

Articles

License

© Dhaka University Journal of Pharmaceutical Sciences

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