Isolation of Bioactive Secondary Metabolites from the Endophytic Fungus of <i>Ocimum basilicum</i>

Authors

  • Md. Aminul Haque Department of Chemistry, University of Dhaka, Dhaka-1000
  • M Shawkat Hossain Department of Chemistry, University of Dhaka, Dhaka-1000
  • MZ Rahman Department of Microbiology, University of Dhaka, Dhaka-1000
  • M Rezaur Rahman Department of Chemistry, University of Dhaka, Dhaka-1000
  • Md. Sohrab Hossain Department of Chemistry, University of Dhaka, Dhaka-1000
  • M Mosihuzzaman Department of Chemistry, University of Dhaka, Dhaka-1000
  • Nilufar Nahar Department of Chemistry, University of Dhaka, Dhaka-1000
  • SI Khan Department of Microbiology, University of Dhaka, Dhaka-1000

DOI:

https://doi.org/10.3329/dujps.v4i2.215

Keywords:

Ocimum basilicum, Secondary Metabolites, Endophytic fungi, Ergosterol, Cerevesterol

Abstract

Twenty three endophytic fungi from leaf, stem and root of 0cimum basilicum (Tulshi) were isolated and purified. One of the fungi (2L-5) isolated from the leaves was fermented in a large scale and extracted with ethyl acetate. The fungal extract was found to be active against two bacteria, Bacillus cereus and Staphylococcus aureus. From the ethyl acetate extract two steroids, ergosterol and cerevisterol were isolated. Structures of the compounds were elucidated by high-resolution 1- and 2-D NMR spectroscopy. Key words: Ocimum basilicum, Secondary Metabolites, Endophytic fungi, Ergosterol, Cerevesterol Dhaka Univ. J. Pharm. Sci. Vol.4(2) 2005 The full text is of this article is available at the Dhaka Univ. J. Pharm. Sci. website

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How to Cite

Haque, M. A., Hossain, M. S., Rahman, M., Rahman, M. R., Hossain, M. S., Mosihuzzaman, M., Nahar, N., & Khan, S. (2007). Isolation of Bioactive Secondary Metabolites from the Endophytic Fungus of <i>Ocimum basilicum</i>. Dhaka University Journal of Pharmaceutical Sciences, 4(2). https://doi.org/10.3329/dujps.v4i2.215

Issue

Vol. 4 No. 2 (2005)

Section

Articles

License

© Dhaka University Journal of Pharmaceutical Sciences

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