Antidiabetic Activity of Stems of Hemipararsite Dendrophthoe falcata Linn. Parasitic Growing on Mangifera indica

Abstract

In the present investigation, we tested the possible cytoprotective and oral hypoglycemic effects of methanolic extract of stems of Dendrophthoe falcata. Besides, total phenolics and total flavonoids were also investigated. The methanolic extract of D. falcata at 200 mg/kg has also shown significant cytoprotective activity (p < 0.05) in alloxan-induced diabetic rats. In addition the extract significantly reduced the elevated level of blood cholesterol (p < 0.01) and triglyceride (p < 0.05). At the same dose level, the extract significantly improved the alloxan-induced reduction of blood protein level (p < 0.01) to normal value.

Key words: Antidiabetic activity, Hemiparasite, Dendrophthoe falcata

doi: 10.3329/dujps.v7i2.2175

Dhaka Univ. J. Pharm. Sci. 7(2): 177-180, 2008 (December)