Antioxidative and Antidiabetic Potentials of the Pneumatophores of Heritiera fomes Buch. Ham.

Authors

  • Mst Serina Sultana Pharmacy Discipline, Life Science School, Khulna University, Khulna 9208, Bangladesh
  • Mimi Golder Pharmacy Discipline, Life Science School, Khulna University, Khulna 9208, Bangladesh
  • Biswajit Biswas Department of Pharmacy, Jashore University of Science and Technology, Jashore 7408, Bangladesh
  • Utpal Kumar Karmakar Pharmacy Discipline, Life Science School, Khulna University, Khulna 9208, Bangladesh
  • Bishwajit Bokshi Pharmacy Discipline, Life Science School, Khulna University, Khulna 9208, Bangladesh
  • Md Jahir Alam Department of Pharmacy, Jahangirnagar University, Savar, Dhaka 1342, Bangladesh
  • Masum Shahriar Department of Pharmacy, Jahangirnagar University, Savar, Dhaka 1342, Bangladesh
  • Samir Kumar Sadhu Pharmacy Discipline, Life Science School, Khulna University, Khulna 9208, Bangladesh

DOI:

https://doi.org/10.3329/dujps.v20i3.59794

Keywords:

Heritiera fomes, Sundri, Sundarbans, antioxidative, antidiabetic, hematological parameters

Abstract

This research work focuses on determining the antidiabetic and antioxidative properties of ethanolic extract of Heriteira fomes pneumatophores. The in vitro antioxidative activity was tested through several qualitative and quantitative assays which revealed the radical scavenging activity of this plant. The in vivo antihyperglycemic activity of plant extract was confirmed by the oral glucose tolerance test in the mice model. The antidiabetic potential was tested on streptozotocin-induced diabetic rats followed by measuring several hematological parameters and lipid profiles where the extract significantly affected those parameters. The results suggest that H. fomes pneumatophores might be a potential source of antioxidative and antidiabetic bioactive compounds.

Dhaka Univ. J. Pharm. Sci. 20(3): 283-291, 2022 (June) Centennial Special Issue

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Published

2022-06-09

How to Cite

Sultana, M. S. ., Golder, M., Biswas, B., Karmakar, U. K., Bokshi, B., Alam, M. J. ., Shahriar, M., & Sadhu, S. K. . (2022). Antioxidative and Antidiabetic Potentials of the Pneumatophores of Heritiera fomes Buch. Ham. Dhaka University Journal of Pharmaceutical Sciences, 20(3), 283–291. https://doi.org/10.3329/dujps.v20i3.59794