TY - JOUR AU - Herlina, Nur AU - Riyanto, Sugeng AU - Martono, Sudibyo AU - Rohman, Abdul PY - 2018/12/04 Y2 - 2024/03/28 TI - Antioxidant Activities, Phenolic and Flavonoid Contents of Methanolic Extract of Stelechocarpus burahol Fruit and its Fractions JF - Dhaka University Journal of Pharmaceutical Sciences JA - Dhaka Univ. J. Pharm. Sci VL - 17 IS - 2 SE - Articles DO - 10.3329/dujps.v17i2.39170 UR - https://banglajol.info/index.php/JPharma/article/view/39170 SP - 153-159 AB - <p>Kepel or <em>Stelechocarpus burahol </em>is an exotic fruit originating from Java, Indonesia. This research was intended to evaluate the antioxidant activities of extracts and fractions of kepel fruit pulp (KFP) based on radical scavenging capability towards 2,2′-azinobis(3-ethylbenzo thiazoline-6-sulphonic acid) diammonium salt (ABTS) and 2,2′-diphenildiphenyl-1-picrylhydrazil radical (DPPH). In this study, the radical scavenging activities were also correlated with total phenolics and flavonoid contents. Among the evaluated samples, the ethyl acetate fraction exhibited the highest antiradical antioxidant activity towards ABTS radical with IC<sub>50</sub> of 0.35 μg/ml, lower than that of vitamin C (as positive control). It also showed highest antiradical activity using DPPH based assay. Methanolic extract had total phenolic content of 58.28 ± 0.37% wt/wt gallic acid equivalent, higher than its fraction. Meanwhile the petroleum ether soluble fraction revealed flavonoid content (76.06 ± 11.9%) as rutin equivalent, among the extract and fractions evaluated. Based on coefficient (R2) values, phenolics and flavonoids contents contributed to 73.09% and 30.99%% towards antiradical scavenging activities, respectively.</p><p>Dhaka Univ. J. Pharm. Sci. 17(2): 153-159, 2018 (December)</p> ER -