TY - JOUR AU - Semwal, D. K. AU - Rawat, U. AU - Bamola, A. AU - Semwal, R. PY - 2009/08/29 Y2 - 2024/03/28 TI - Antimicrobial Activity of Phoebe lanceolata and Stephania glabra; Preliminary Screening Studies JF - Journal of Scientific Research JA - J. Sci. Res. VL - 1 IS - 3 SE - Section B: Chemical and Biological Sciences DO - 10.3329/jsr.v1i3.2423 UR - https://banglajol.info/index.php/JSR/article/view/2423 SP - 662-666 AB - <p class="MsoNormal" style="margin: 0cm 15.55pt 0pt 14.2pt; text-align: justify; mso-layout-grid-align: none;"><span style="font-family: Times New Roman;"><span style="font-size: 9pt;" lang="EN-US">Ethanolic extracts of <em style="mso-bidi-font-style: normal;">Phoebe lanceolata</em> stem bark and <em style="mso-bidi-font-style: normal;">Stephania glabra</em> tubers were evaluated for their antibacterial and antifungal activities against five bacterial species, <em style="mso-bidi-font-style: normal;">Staphylococcus aureus </em>(along with ten hospital strains)<em style="mso-bidi-font-style: normal;">, Staphylococcus mutans</em>, <em style="mso-bidi-font-style: normal;">Staphylococcus epidermidis, Escherichia coli, Klebsiella pneumoniae </em>and six fungal species <em style="mso-bidi-font-style: normal;">Aspergillus niger, Aspergillus fumigatus, Penicillum citranum, Microsporum gypseum, Microsporum canis,</em> <em style="mso-bidi-font-style: normal;">Trichophyton rubrum,</em> obtained from different culture media. The plants/parts extracts were found active against most of the tested microorganism with MIC range of 50-100&micro;g/ml. T</span><span style="font-size: 9pt; mso-bidi-language: HI;" lang="EN-US">he MIC was taken at the lower concentration where inhibition ceased. Novobiocin (15 &micro;g/ml) and erythromycin (15 &micro;g/ml) were used as positive controls for bacterial and fungus species respectively. </span></span></p><p class="MsoNormal" style="margin: 0cm 15.55pt 0pt 14.2pt; text-align: justify; mso-layout-grid-align: none;"><span style="font-size: 4pt; mso-bidi-font-size: 9.0pt;" lang="EN-US"><span style="font-family: Times New Roman;">&nbsp;</span></span></p><p class="MsoNormal" style="margin: 0cm 15.55pt 0pt 14.2pt; text-align: justify;"><span style="font-family: Times New Roman;"><em style="mso-bidi-font-style: normal;"><span style="font-size: 9pt;" lang="EN-US">Keywords:</span></em><span style="font-size: 9pt;" lang="EN-US">Antimicrobial activity; <em style="mso-bidi-font-style: normal;">Streptococcus mutans;</em><em style="mso-bidi-font-style: normal;"> Klebsiella pneumoniae;</em><em style="mso-bidi-font-style: normal;"> Microsporum gypseum;</em> Nutrient and Sabouraud&rsquo;s dextrose agar medium.</span></span></p><p class="MsoNormal" style="margin: 0cm 0cm 0pt 14.2pt; mso-layout-grid-align: none;"><span style="font-size: 6pt; mso-bidi-font-size: 10.0pt;" lang="EN-US"><span style="font-family: Times New Roman;">&nbsp;</span></span></p><p class="MsoNormal" style="margin: 0cm 0cm 0pt 14.2pt; mso-layout-grid-align: none;"><span style="font-size: 8pt; mso-ansi-language: EN-SG; mso-fareast-language: EN-SG;"><span style="font-family: Times New Roman;">&copy; 2009 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights reserved.</span></span></p><p class="MsoNormal" style="margin: 0cm 0cm 0pt 14.2pt; tab-stops: 14.2pt 6.0cm 177.2pt 184.3pt;"><span style="font-size: 4pt; mso-bidi-font-size: 8.0pt; mso-ansi-language: EN-SG; mso-fareast-language: EN-SG;"><span style="font-family: Times New Roman;">&nbsp;</span></span></p><p class="MsoNormal" style="margin: 0cm 0cm 0pt 14.2pt; tab-stops: 14.2pt 6.0cm 177.2pt 184.3pt;"><span style="font-family: Times New Roman;"><span style="font-size: 8pt; mso-ansi-language: EN-SG; mso-fareast-language: EN-SG;">DOI: 10.3329/jsr.v1i3.2423<span style="mso-spacerun: yes;">&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; </span></span><span style="font-size: 8pt;" lang="EN-US">J. Sci. Res. <strong style="mso-bidi-font-weight: normal;">1</strong> (3), 662-666 (2009)</span></span></p><p>&nbsp;</p> ER -