TY - JOUR AU - Mostofa, Hasbi Ara AU - Shamsuzzaman, SM AU - Hasan, Md Maniul AU - Shormin, Moonmoon AU - Das, Bithi AU - Habiba, Umme AU - Rahman, Md Mustafizur AU - Akhter, Shakila PY - 2021/01/24 Y2 - 2024/03/28 TI - Imipenem Resistance Gram-Negative Bacilli Isolated from Patients of a Tertiary Care Hospital in Dhaka, Bangladesh JF - Journal of Shaheed Suhrawardy Medical College JA - J Shaheed Suhrawardy Med Coll VL - 12 IS - 1 SE - Original Articles DO - 10.3329/jssmc.v12i1.51610 UR - https://banglajol.info/index.php/JSSMC/article/view/51610 SP - 3-5 AB - <p><strong>Introduction: </strong>The emergence of antibiotics resistance bacteria is a persistent global problem affecting public health. The occurrence and widespread resistance to Imipenem among hospital bacterial isolates can constitute a significant threat to chemotherapy.</p><p><strong>Objectives</strong>: This cross-sectional study aimed to investigate the imipenem resistant pattern among gram-negative bacilli isolated from different samples in Dhaka medical college hospital.</p><p><strong>Methods: </strong>A total of 300 samples (wound swab, urine, endotracheal aspirate, blood, and sputum) were collected from July 2015 to June 2016. Two hundred four gram-negative bacilli were isolated and tested for resistance to imipenem by the disc diffusion method.</p><p><strong>Results: </strong>Among 204-gram negative bacilli, 39.21% imipenem resistance was detected by the Disc Diffusion method. 14.7% imipenem resistance gram-negative bacilli were from wound swab. 83.33% of Acinetobacter baumannii were Imipenem resistant.</p><p><strong>Conclusions: </strong>Imipenem resistance is widespread among gram-negative bacilli isolated from human infections. Imipenem resistance (39.21%) found in the study is quite worrisome.</p><p>J Shaheed Suhrawardy Med Coll, December 2020, Vol.12(1); 3-5</p> ER -