Histomorphometric Study of the Proportion of Cortex and Medulla of the Adrenal Gland-A Postmortem Study

Authors

  • Dilruba Siddiqua Department of Anatomy, Ibn Sina Medical College, Dhaka, Bangladesh
  • Abu Sadat Mohammad Nurunnabi Assistant Professor, Department of Anatomy,OSD, Directorate General of Health Services (DGHS), Dhaka, Bangladesh
  • Fatema Johora Associate Professor, Department of Anatomy, Sir Salimullah Medical College, Dhaka, Bangladesh
  • Hasna Hena Associate Professor, Department of Anatomy, East West Medical College, Dhaka, Bangladesh
  • Sunjida Shahriah Professor & Head, Department of Anatomy, Marks Medical College and Hospital, Mirpur, Dhaka, Bangladesh
  • Shamim Ara Professor & Head, Department of Anatomy, Holy Family Red Crescent Medical College, Dhaka, Bangladesh

DOI:

https://doi.org/10.3329/mediscope.v8i1.52198

Keywords:

Human adrenal gland, Adrenal cortex, Adrenal medulla

Abstract

Background: The human adrenal gland shows a distinct proportion of two histological zones, named the cortex and the medulla, from outer inwards, in its histological appearance with differences in its cellular components and functions.

Objective: The present study aims to see the variation in the proportion of the cortex and the medulla of the adrenal glands with age in a Bangladeshi population.

Methods: A cross-sectional, descriptive study was done in the Department of Anatomy, Dhaka Medical College, Dhaka, from July 2008 to June 2009, based on collection of 140 postmortem human adrenal glands from 70 unclaimed dead bodies, in the Department of Forensic Medicine, Dhaka Medical College, Dhaka. The samples were divided into four age-groups including A (11-20 years), B (21-30 years), C (31-40 years) & D (41-60 years). Histological slides were prepared by using routine haematoxylin and eosin stain (H & E). Five best prepared slides from each group were examined under light compound microscope with low magnification. The thickness of adrenal cortex and medulla were measured by using ocular and stage micrometer and then converted into percentage volume.

Results: The mean volume of the right adrenal cortex were found 83.64±3.71% in group A, 83.90±1.75% in group B, 83.74±5.78% in group C, 84.80±3.82% in group D, while the mean volume of the corresponding medulla were found 18.16±3.23% in group A, 15.70±2.71% in group B, 16.26±3.97% in group C, 16.20±4.04% in group D. The mean volume of the left adrenal cortex were found 84.64±3.49%, 84.90±1.75%, 84.20±3.40%, 85.44±2.66% in group A, B, C and D respectively, while the mean volume of the corresponding medulla were found 17.26±3.84%, 17.00±2.37%, 16.00±3.20% and 14.36±2.33% in group A, B, C and D respectively. The differences among the groups were not statistically significant.

Conclusion: No difference was found in the proportion of the cortex and the medulla of adrenal gland in different age-groups.

Mediscope Vol. 8, No. 1: January 2021, Page 1-6

Downloads

Download data is not yet available.
Abstract
60
PDF
35

Downloads

Published

2021-03-01

How to Cite

Siddiqua, D., Nurunnabi, A. S. M., Johora, F., Hena, H., Shahriah, S., & Ara, S. (2021). Histomorphometric Study of the Proportion of Cortex and Medulla of the Adrenal Gland-A Postmortem Study. Mediscope, 8(1), 1–6. https://doi.org/10.3329/mediscope.v8i1.52198

Issue

Vol. 8 No. 1 (2021)

Section

Original Articles

License

Authors who publish in the Mediscope agree to the following terms that:

  1. Authors retain copyright and grant Mediscope the right of first publication of the work.

  2. Creative Commons Licence
    Articles in Mediscope are licensed under a Creative Commons Attribution 4.0 International License CC BY-4.0. This license permits use, distribution and reproduction in any medium, provided the original work is properly cited.
  1. Authors are able to enter into separate, additional contractual arrangements for the distribution of the journal’s published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  2. Authors are permitted to post their work online (e.g., in institutional repositories or on their website) as it can lead to productive exchanges, as well as greater citation of published work.